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We report an 8\u2010year\u2010old boy with homozygous sickle cell disease and severe atopic dermatitis who developed diffuse pruritic violaceous papules followed by tense bullae; subsequent histopathologic, immunofluorescence, and serologic findings confirmed LPP. The patient was initially treated with cyclosporine, with marked clinical improvement within 2\u20133\u2009weeks. Dupilumab was subsequently initiated during the cyclosporine taper, and no recurrent bullae were observed through approximately 8\u2009months of follow\u2010up.<\/jats:p>","DOI":"10.1111\/pde.70360","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:21:56Z","timestamp":1791465716000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pediatric Lichen Planus Pemphigoides in a Child With Sickle Cell Disease: Cyclosporine Induction and Dupilumab Maintenance"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3272-6778","authenticated-orcid":false,"given":"Yumeng T.","family":"Engelking","sequence":"first","affiliation":[{"name":"University of Iowa Carver College of Medicine  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Correa","family":"Ferrer","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Iowa Hospitals and Clinics  Iowa City Iowa USA"},{"name":"Department of Pediatrics University of Iowa Hospitals and Clinics  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8967-0470","authenticated-orcid":false,"given":"Jazmin","family":"Newton","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Iowa Hospitals and Clinics  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8537-3647","authenticated-orcid":false,"given":"Kristen G.","family":"Berrebi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Children's Hospital Colorado University of Colorado  Aurora Colorado 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