{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T01:08:28Z","timestamp":1789348108857,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>We present the case of a 10\u2010year\u2010old female with anaplastic lymphoma kinase protein (ALK) negative systemic anaplastic large cell lymphoma (ALCL) with cutaneous manifestations that achieved complete remission after multi\u2010agent chemotherapy. Approximately 6\u2009months after remission, the patient experienced a relapse of ALK\u2010negative ALCL confined exclusively to the skin. Four months after completing salvage therapy, she developed a second isolated cutaneous relapse. This case highlights the diagnostic challenge of distinguishing systemic ALCL from primary cutaneous ALCL and other primary cutaneous CD30+ lymphoproliferative disorders.<\/jats:p>","DOI":"10.1111\/pde.70361","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:50:59Z","timestamp":1789347059000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pediatric\n                    <scp>ALK<\/scp>\n                    \u2010Negative Anaplastic Large Cell Lymphoma With Recurrent Cutaneous Relapses: Diagnostic Challenges"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7478-9046","authenticated-orcid":false,"given":"Kayla","family":"Coffman","sequence":"first","affiliation":[{"name":"Marshall University Joan C. Edwards School of Medicine  Huntington West Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0708-2494","authenticated-orcid":false,"given":"Emily","family":"Saurborn","sequence":"additional","affiliation":[{"name":"Marshall University Joan C. Edwards School of Medicine  Huntington West Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dylan","family":"Maldonado","sequence":"additional","affiliation":[{"name":"Department of Dermatology Marshall University Joan C. Edwards School of Medicine  Huntington West Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7821-7530","authenticated-orcid":false,"given":"Paul","family":"Finch","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology and Oncology Marshall University Joan C. Edwards School of Medicine  Huntington West Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shane","family":"Cook","sequence":"additional","affiliation":[{"name":"Department of Dermatology Marshall University Joan C. Edwards School of Medicine  Huntington West Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.20154"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13184667"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.12.053"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers10040099"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14071650"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/JEP.S262344"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2012.065664"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375\u2010022\u201001620\u20102"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15164098"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2016.11.006"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood\u20102011\u201005\u2010351346"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljae150"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0000000000000047"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers10040107"},{"key":"e_1_2_8_16_1","unstructured":"S. H.Swerdlow E. S.Jaffe N. L.Harris et\u00a0al. \u201cWHO Classification of Tumours of Haematopoietic and Lymphoid Tissues \u201d accessed June 20 2026 https:\/\/publications.iarc.who.int\/Book\u2010And\u2010Report\u2010Series\/Who\u2010Classification\u2010Of\u2010Tumours\/WHO\u2010Classification\u2010Of\u2010Tumours\u2010Of\u2010Haematopoietic\u2010And\u2010Lymphoid\u2010Tissues\u20102017."},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16501"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells11223697"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.59.7203"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.70361","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.70361","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.70361","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:51:07Z","timestamp":1789347067000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.70361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,13]]},"references-count":18,"alternative-id":["10.1111\/pde.70361"],"URL":"https:\/\/doi.org\/10.1111\/pde.70361","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,13]]},"assertion":[{"value":"2026-01-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"pde.70361"}}