{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T10:00:44Z","timestamp":1772532044984,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,6,18]],"date-time":"2013-06-18T00:00:00Z","timestamp":1371513600000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Orbital abscess is life\u2010threatening and rare in children. Reported herein is a term male neonate who had methicillin\u2010resistant <jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>taphylococcus aureus<\/jats:italic> orbital abscess, and a literature review of this disease. A total of 16 neonates diagnosed with neonatal orbital abscess are reported in the literature. There is a mild male predilection and two neonates were delivered prematurely. Leukocytosis, fever, ethmoiditis and associated upper respiratory tract infection were found in approximately half of them. Eight neonates had sepsis and 14 patients underwent surgical intervention. One patient died. <jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>taphylococcus aureus<\/jats:italic> was identified in 14 out of 17 patients. Neonatal orbital abscess is rarely encountered but may be fatal. Although streptococci are prevalent in childhood orbital infection, <jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>.\u2009aureus<\/jats:italic> was predominant in neonatal orbital abscess in the present series. Appropriate antimicrobial therapy against <jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>.\u2009aureus<\/jats:italic> is essential in treating neonatal orbital abscess. This case suggests that a higher initial dose of vancomycin may be an effective and safe strategy for severe <jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>.\u2009aureus<\/jats:italic> infection in neonates.<\/jats:p>","DOI":"10.1111\/ped.12020","type":"journal-article","created":{"date-parts":[[2013,6,19]],"date-time":"2013-06-19T03:25:44Z","timestamp":1371612344000},"source":"Crossref","is-referenced-by-count":18,"title":["Neonatal orbital abscess"],"prefix":"10.1111","volume":"55","author":[{"given":"Chien\u2010Yu","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Pediatrics Hsinchu Mackay Memorial Hospital  Hsinchu City"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan\u2010Chang","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Mackay Memorial Hospital  Taipei Taiwan"},{"name":"Mackay Medicine, Nursing and Management College Taipei Medical University  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuo\u2010Sheng","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Mackay Memorial Hospital  Taipei Taiwan"},{"name":"Mackay Medicine, Nursing and Management College Taipei Medical University  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fu\u2010Yuan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Mackay Memorial Hospital  Taipei Taiwan"},{"name":"Department of Pediatrics Taipei Medical University  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chyong\u2010Hsin","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Mackay Memorial Hospital  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,18]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(01)00859-4"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004397-200110000-00009"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2009.10.002"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.43.1.9"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1979.tb00512.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100125228"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(99)00042-7"},{"key":"e_1_2_4_9_1","doi-asserted-by":"crossref","first-page":"358","DOI":"10.3928\/0191-3913-20021101-13","article-title":"Orbital cellulitis secondary to tooth bud abscess in a neonate","volume":"39","author":"Green LK","year":"2002","journal-title":"J. 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