{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:15:09Z","timestamp":1761743709710},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,4,16]],"date-time":"2013-04-16T00:00:00Z","timestamp":1366070400000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The role of pet exposure in childhood asthma and allergy is still controversial. The aim of this study was to investigate the association between pet\u2010keeping during different periods of childhood and asthma and sensitization in school children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred and forty\u2010nine children aged between 7 and 14 years were enrolled in this study. Seventy\u2010four children had current physician\u2010diagnosed asthma, while 75 children did not have asthma. Pet\u2010keeping was investigated by questionnaire. Allergic sensitization to pet allergen was assessed on skin prick tests and specific serum <jats:styled-content style=\"fixed-case\">IgE<\/jats:styled-content> concentration. Logistic regression analysis was performed, taking into account potential confounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Early, past and current pet\u2010keeping was not significantly associated with asthma. Neither owning a cat nor dog during childhood was associated with asthma. Early pet\u2010keeping, however, was significantly associated with sensitization to pet allergens (adjusted odds ratio [<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>], 24.11; 95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>]: 3.28\u2013177.27). Further analysis showed that only early cat\u2010keeping was significantly associated with sensitization to cat allergen (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>, 51.59; 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 2.28\u20131167.07). Keeping a cat or a dog after the first year of life was not associated with sensitization to those allergens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Keeping a cat or a dog does not increase risk for asthma. Keeping a cat in the first year of life, however, increases risk of sensitization to cat allergen. Considering that this is a relatively small study, larger, prospective, birth cohort studies are required in Serbia to accurately assess the relationship between pet\u2010keeping, asthma and sensitization.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.12071","type":"journal-article","created":{"date-parts":[[2013,2,20]],"date-time":"2013-02-20T10:59:09Z","timestamp":1361357949000},"page":"133-137","source":"Crossref","is-referenced-by-count":19,"title":["Association between pet\u2010keeping and asthma in school children"],"prefix":"10.1111","volume":"55","author":[{"given":"Biljana","family":"Medjo","sequence":"first","affiliation":[{"name":"Pediatric Intensive Care Unit University Children's Hospital"},{"name":"Medical Faculty University of Belgrade  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Atanaskovic\u2010Markovic","sequence":"additional","affiliation":[{"name":"Department of Pulmonology and Allergology University Children's Hospital"},{"name":"Medical Faculty University of Belgrade  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrije","family":"Nikolic","sequence":"additional","affiliation":[{"name":"Department of Neurology University Children's Hospital"},{"name":"Medical Faculty University of Belgrade  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brankica","family":"Spasojevic\u2010Dimitrijeva","sequence":"additional","affiliation":[{"name":"Department of Nephrology University Children's Hospital"},{"name":"Medical Faculty University of Belgrade  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petar","family":"Ivanovski","sequence":"additional","affiliation":[{"name":"Department of Pediatric Clinic University Children's Hospital"},{"name":"Medical Faculty University of Belgrade  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Slobodanka","family":"Djukic","sequence":"additional","affiliation":[{"name":"Institute of Microbiology and Immunology"},{"name":"Medical Faculty University of Belgrade  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,4,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.54.1.27"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.2003.00050.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.2001.00387.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0668.1998.00003.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.113240"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2002.128948"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.117797"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2201035"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.8.963"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.2000.00802.x"},{"key":"e_1_2_5_12_1","unstructured":"Global Strategy for Asthma Management and Prevention.Global Initiative for Asthma (GINA) 2009. 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