{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T05:09:08Z","timestamp":1716613748662},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,8,5]],"date-time":"2013-08-05T00:00:00Z","timestamp":1375660800000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Giardiasis is a common cause of diarrhea in undeveloped countries, but is very rare in developed countries. A patient with acute myelogenous leukemia and retinoblastoma presented with a high fever and severe watery diarrhea during induction chemotherapy. On microscopy, cysts were seen in her stool, suggesting <jats:italic><jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>iardia intestinalis<\/jats:italic>, which was confirmed on polymerase chain reaction (<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>). <jats:italic><jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>.\u2009intestinalis<\/jats:italic> was also detected in the patient's asymptomatic parents, who may have transmitted it to the patient. Giardiasis should be tested for in patients with severe and persistent diarrhea during chemotherapy, when other etiologies have been excluded. <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> used to amplify the <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> of <jats:italic><jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>.\u2009intestinalis<\/jats:italic> is rapid and sensitive.<\/jats:p>","DOI":"10.1111\/ped.12078","type":"journal-article","created":{"date-parts":[[2013,8,5]],"date-time":"2013-08-05T08:19:41Z","timestamp":1375690781000},"page":"524-527","source":"Crossref","is-referenced-by-count":1,"title":["Giardiasis in a patient undergoing chemotherapy for retinoblastoma and acute myelogenous leukemia"],"prefix":"10.1111","volume":"55","author":[{"given":"Keisuke","family":"Otsubo","sequence":"first","affiliation":[{"name":"Department of Pediatrics Graduate School of Medicine and Pharmaceutical Sciences University of Toyama  Toyama"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisano","family":"Sakaki\u2010Nakatsubo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Graduate School of Medicine and Pharmaceutical Sciences University of Toyama  Toyama"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromichi","family":"Taneichi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Graduate School of Medicine and Pharmaceutical Sciences University of Toyama  Toyama"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Graduate School of Medicine and Pharmaceutical Sciences University of Toyama  Toyama"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshio","family":"Miyawaki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Graduate School of Medicine and Pharmaceutical Sciences University of Toyama  Toyama"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaharu","family":"Tokoro","sequence":"additional","affiliation":[{"name":"Department of Parasitology Kanazawa University Graduate School of Medicine  Kanazawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Kanegane","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Graduate School of Medicine and Pharmaceutical Sciences University of Toyama  Toyama"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,8,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.42.222"},{"key":"e_1_2_5_3_1","first-page":"701","article-title":"Severe giardiasis in two patients undergoing bone marrow transplantation","volume":"4","author":"Bromiker R","year":"1989","journal-title":"Bone Marrow Transplant."},{"key":"e_1_2_5_4_1","first-page":"450","article-title":"Severe giardiasis in a child during cancer therapy","volume":"84","author":"Korman SH","year":"1989","journal-title":"Am. 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