{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T20:39:10Z","timestamp":1769632750084,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,8,21]],"date-time":"2013-08-21T00:00:00Z","timestamp":1377043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We conducted a comparative clinical study to evaluate the prophylactic effects of micafungin (<jats:styled-content style=\"fixed-case\">MCFG<\/jats:styled-content>) and fluconazole (<jats:styled-content style=\"fixed-case\">FLCZ<\/jats:styled-content>) on the incidence of fungal infections in extremely low\u2010birthweight infants who were born at a gestational age of less than 26 weeks and weighed less than 1000\u2009g.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>With a combination of enteral administration of miconazole (6\u2009mg\/kg\/day), <jats:styled-content style=\"fixed-case\">FLCZ<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MCFG<\/jats:styled-content> were administered intravenously at a dose of 5\u2009mg\/kg\/day and 3\u2009mg\/kg\/day, respectively. The prophylaxis was classified as a failure when fungal infections were identified within the first 21 days after birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prophylaxis was successful in seven of 18 cases (39%) in the <jats:styled-content style=\"fixed-case\">FLCZ<\/jats:styled-content> group and 15 of 21 cases (71%) in the <jats:styled-content style=\"fixed-case\">MCFG<\/jats:styled-content> group, indicating that the success rate was significantly higher in the latter group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">MCFG<\/jats:styled-content> was superior to <jats:styled-content style=\"fixed-case\">FLCZ<\/jats:styled-content> as prophylaxis against fungal infections in extremely low\u2010birthweight infants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.12157","type":"journal-article","created":{"date-parts":[[2013,6,17]],"date-time":"2013-06-17T10:26:03Z","timestamp":1371464763000},"page":"727-730","source":"Crossref","is-referenced-by-count":10,"title":["Micafungin versus fluconazole for prophylaxis against fungal infections in premature infants"],"prefix":"10.1111","volume":"55","author":[{"given":"Yoshinobu","family":"Maede","sequence":"first","affiliation":[{"name":"Department of Neonatology, Perinatal Medical Center Kagoshima City Hospital  Kagoshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Ibara","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Perinatal Medical Center Kagoshima City Hospital  Kagoshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiraku","family":"Nagasaki","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Perinatal Medical Center 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