{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T03:19:35Z","timestamp":1778901575765,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,9,20]],"date-time":"2013-09-20T00:00:00Z","timestamp":1379635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Rheumatic fever and rheumatic heart disease continue to be an important public health problem in developing countries. <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>oppler echocardiography is now widely used for early detection and recurrence of clinical evident carditis (<jats:styled-content style=\"fixed-case\">CC<\/jats:styled-content>) and silent (subclinical) carditis (<jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>). The aim of this study was to determine the frequency of <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content> and to compare clinical and echocardiographic features of <jats:styled-content style=\"fixed-case\">CC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 156 consecutive patients diagnosed with acute rheumatic fever were included in the study. The patients without clinical evidence but with echocardiographic findings of carditis were diagnosed as having <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Acute rheumatic fever was diagnosed in 156 patients, and 103 of these (66%) had carditis. The prevalence of <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content> was 28.2% among these 103 patients. Seventy\u2010four of the patients with carditis were followed up for &gt;1 year, and 20 of those had <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>. Valvular regurgitation disappeared completely in 18.5% and improved in 45.5% of the <jats:styled-content style=\"fixed-case\">CC<\/jats:styled-content> patients. The recovery and improvement rates in the <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content> group were 15% and 30%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>It is suggested that <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>oppler echocardiography be performed in all patients with suspected acute rheumatic fever for early detection of <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>. Echocardiography should be used as a diagnostic criterion in order not to miss a diagnosis of <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.12163","type":"journal-article","created":{"date-parts":[[2013,6,24]],"date-time":"2013-06-24T03:28:05Z","timestamp":1372044485000},"page":"685-689","source":"Crossref","is-referenced-by-count":12,"title":["Rheumatic silent carditis: Echocardiographic diagnosis and prognosis of long\u2010term follow up"],"prefix":"10.1111","volume":"55","author":[{"given":"Esra","family":"Pekpak","sequence":"first","affiliation":[{"name":"Department of Pediatrics Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Semra","family":"Atalay","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cem","family":"Karadeniz","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fikri","family":"Demir","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ercan","family":"Tutar","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tayfun","family":"U\u00e7ar","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,20]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2010.01841.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-0825.2002.1o816.x"},{"key":"e_1_2_5_4_1","first-page":"2069","article-title":"Guidelines for the diagnosis of rheumatic fever. 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