{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T05:48:12Z","timestamp":1696225692307},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,1,28]],"date-time":"2014-01-28T00:00:00Z","timestamp":1390867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>During the <jats:styled-content style=\"fixed-case\">A\/H1N1<\/jats:styled-content> pandemic, patients suffered from impaired consciousness. They were suspected of or diagnosed as having influenza\u2010associated encephalopathy (IAE) in an emergency situation. Their symptoms resembled those of a recently described \u2018unique clinical group\u2019, which were reported to have a favorable prognosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively examined 46 patients and divided them into two groups. Group <jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content> contained the 26 patients with persisting impaired consciousness. The remainder of the patients were categorized into group <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>, consisting of patients with only neurological symptoms without impaired consciousness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Male predominance (22 male\/four female) was noted in group <jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content>. Patient age ranged from 5 to 12 years old (mean \u00b1 <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>, 7.7 \u00b1 2.3 years). Impaired consciousness such as delirious behavior or mild reduction of consciousness lasted continuously or intermittently from 5\u2009min to 2.5 days. On electroencephalogram, semi\u2010rhythmic high\u2010voltage slow waves in the parieto\u2010occipital regions and diffuse high\u2010voltage slow waves were observed in eight and in two patients, respectively. In group <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>, there was no gender predominance. Patient age ranged from 1 to 9 years old (mean \u00b1 <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>, 4.1 \u00b1 2.5 years). All group <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content> patients were clinically diagnosed with febrile seizure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Some of the characteristics in group <jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content> resembled those of the unique clinical group, and are part of a continuous clinical spectrum. Some patients may have favorable outcome without specific treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.12240","type":"journal-article","created":{"date-parts":[[2013,10,28]],"date-time":"2013-10-28T12:03:12Z","timestamp":1382961792000},"page":"244-247","source":"Crossref","is-referenced-by-count":0,"title":["Delirious behavior or mild reduction of consciousness mimicking influenza\u2010associated encephalopathy"],"prefix":"10.1111","volume":"56","author":[{"given":"Kohji","family":"Azumagawa","sequence":"first","affiliation":[{"name":"Department of Pediatrics Seikeikai Hospital  Sakai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuru","family":"Kashiwagi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Hirakata Municipal Hospital  Hirakata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuichi","family":"Shimakawa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Osaka Medical College  Takatsuki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuya","family":"Tanabe","sequence":"additional","affiliation":[{"name":"Department of Child Neurology Tanabe Kadobayashi Children's Clinic  Hirakata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Tamai","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Osaka Medical College  Takatsuki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,28]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Guideline for Influenza Encephalopathy: A Revised Edition","author":"The Research Committee on the Clarification of Etiology and on the Establishment of Treatment of Therapeutic and Preventive Measures of Influenza Encephalopathy","year":"2009"},{"key":"e_1_2_6_3_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"1994"},{"key":"e_1_2_6_4_1","first-page":"310","article-title":"Differential diagnosis in children having delirium associated with high fever (in Japanese)","volume":"35","author":"Kashiwagi M","year":"2003","journal-title":"No To Hattatsu"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2011.07.012"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2007.00809.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000144274.12174.CB"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2008.00279.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1295411"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2006.12.005"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2007.08.008"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2008.04.002"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2008.00100.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2008.07.013"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2010.02.013"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2011.03454.x"}],"container-title":["Pediatrics International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.12240","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.12240","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T08:33:50Z","timestamp":1696149230000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ped.12240"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,28]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1111\/ped.12240"],"URL":"https:\/\/doi.org\/10.1111\/ped.12240","archive":["Portico"],"relation":{},"ISSN":["1328-8067","1442-200X"],"issn-type":[{"value":"1328-8067","type":"print"},{"value":"1442-200X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,28]]}}}