{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T09:10:12Z","timestamp":1764493812392,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,5,30]],"date-time":"2014-05-30T00:00:00Z","timestamp":1401408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2014,8]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Most infants with pneumothorax have underlying conditions. P<\/jats:styled-content>neumocystis jirovecii<\/jats:italic> pneumonia (PCP<\/jats:styled-content>) frequently occurs in patients with severe combined immunodeficiency (SCID<\/jats:styled-content>). The aim of this study was to determine clinical features of PCP<\/jats:styled-content>\u2010associated pneumothorax in SCID<\/jats:styled-content> patients.<\/jats:p><\/jats:sec>Methods<\/jats:title>The medical records of four SCID<\/jats:styled-content> patients with pneumothorax were retrospectively reviewed.<\/jats:p><\/jats:sec>Results<\/jats:title>All four patients were diagnosed as having SCID<\/jats:styled-content> at the time of contracting PCP<\/jats:styled-content>. All patients received mechanical ventilation because of severe respiratory failure. Only one patient was successfully extubated and was alive following hematopoietic stem cell transplantation (HSCT<\/jats:styled-content>); of the remaining patients, however, two died of respiratory failure, and one patient died of early HSCT<\/jats:styled-content>\u2010related complications.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Pneumothorax associated with PCP<\/jats:styled-content> can occur in SCID<\/jats:styled-content> patients, and they may have a poor prognosis. If pneumothorax occurs in infants, both respiratory management and prompt investigation of the underlying conditions are needed, considering the possibility of PCP<\/jats:styled-content> associated with SCID<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.12325","type":"journal-article","created":{"date-parts":[[2014,3,10]],"date-time":"2014-03-10T12:57:17Z","timestamp":1394456237000},"page":"510-514","source":"Crossref","is-referenced-by-count":4,"title":["Pneumothorax in patients with severe combined immunodeficiency"],"prefix":"10.1111","volume":"56","author":[{"given":"Akihiro","family":"Hoshino","sequence":"first","affiliation":[{"name":"Department of Pediatrics Graduate School of Medicine and Pharmaceutical Sciences University of Toyama Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohsuke","family":"Imai","sequence":"additional","affiliation":[{"name":"Department of Community Pediatrics Perinatal and Maternal Medicine Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4488-0308","authenticated-orcid":false,"given":"Yusei","family":"Ohshima","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medical Sciences University of Fukui Eiheiji Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoko","family":"Yasutomi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medical Sciences University of Fukui Eiheiji Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Kasai","sequence":"additional","affiliation":[{"name":"Department of General Pediatrics Nagano Children's Hospital Azumino Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaru","family":"Terai","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Tokyo Women's Medical University, Yachiyo Medical 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