{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T07:29:31Z","timestamp":1767338971448},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,10,15]],"date-time":"2014-10-15T00:00:00Z","timestamp":1413331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2014,12]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>The supportive clinical and pathophysiological data about the correlation between migraine and atopic disorders are far from a coincidence. In order to determine and investigate the correlates of atopic disorders in a specific dataset, we performed this retrospective cross\u2010sectional clinical\u2010based study.<\/jats:p><\/jats:sec>Methods<\/jats:title>The dataset was composed from three tertiary center web\u2010based databases (http:\/\/www.childhoodheadache.org<\/jats:ext-link>). Headache diagnosis and differential diagnosis were made according to the I<\/jats:styled-content>nternational C<\/jats:styled-content>lassification of H<\/jats:styled-content>eadache D<\/jats:styled-content>isorders, 2nd version and the D<\/jats:styled-content>iagnostic S<\/jats:styled-content>tatistical M<\/jats:styled-content>anual of M<\/jats:styled-content>ental D<\/jats:styled-content>isorders<\/jats:italic>, 5th edition. Migraine with aura, migraine without aura, chronic migraine and episodic and chronic tension type headache (TTH<\/jats:styled-content>) patients were included. All other causes of headache disorders, including comorbid headache disorders like migraine plus TTH<\/jats:styled-content> or \u201cpossible\u201d causes of headache, were excluded.<\/jats:p><\/jats:sec>Results<\/jats:title>The study included 438 patients with migraine and 357 patients with TTH<\/jats:styled-content>, whose age and sex distribution were identical. After descriptive statistics accordingly, 80 migraine (18.2%) and 23 TTH<\/jats:styled-content> (6.4%) patients were found to have specific atopic disorders (P<\/jats:italic> < 0.001). Atopic disorders are more commonly reported in patients with migraine with aura (21.6%) than those with migraine without aura and TTH<\/jats:styled-content> (P<\/jats:italic> < 0.001). The most common atopic disorders were seasonal rhinitis, conjunctivitis and asthma. There was also a close correlation between TTH<\/jats:styled-content> with atopic disorders and psychiatric comorbid disorders of the patients.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Although the I<\/jats:styled-content>nternational C<\/jats:styled-content>lassification of H<\/jats:styled-content>eadache D<\/jats:styled-content>isorders, 2nd version, does not specify, atopic disorders should be suspected in all migraine patients and their relatives, not only for accurate diagnosis but also for planning prophylactic medications, such as \u03b2\u2010blockers.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.12381","type":"journal-article","created":{"date-parts":[[2014,5,19]],"date-time":"2014-05-19T11:19:42Z","timestamp":1400498382000},"page":"868-872","source":"Crossref","is-referenced-by-count":26,"title":["Atopic disorders are more common in childhood migraine and correlated headache phenotype"],"prefix":"10.1111","volume":"56","author":[{"given":"Aynur","family":"\u00d6zge","sequence":"first","affiliation":[{"name":"Department of Neurology Mersin University School of Medicine Mersin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nevra","family":"\u00d6ks\u00fcz","sequence":"additional","affiliation":[{"name":"Department of Neurology Mersin University School of Medicine Mersin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Semih","family":"Ayta","sequence":"additional","affiliation":[{"name":"Department of Neurology Maltepe University School of Medicine Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derya","family":"Uluduz","sequence":"additional","affiliation":[{"name":"Department of Neurology Istanbul University Cerrahpasa School of Medicine Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veli","family":"Y\u0131ld\u0131r\u0131m","sequence":"additional","affiliation":[{"name":"Department of Neurology Mersin University School of Medicine Mersin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fevziye","family":"Toros","sequence":"additional","affiliation":[{"name":"Department of Neurology Mersin University School of Medicine Mersin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bahar","family":"Ta\u015fdelen","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Mersin University School of Medicine Mersin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102409351797"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2009.00791.x"},{"issue":"482","key":"e_1_2_7_4_1","first-page":"723","article-title":"Association between migraine and asthma: matched case\u2010control study","volume":"52","author":"Davey G","year":"2002","journal-title":"Br. 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