{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T13:02:55Z","timestamp":1761310975997},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,9,24]],"date-time":"2014-09-24T00:00:00Z","timestamp":1411516800000},"content-version":"vor","delay-in-days":54,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Congenital toxoplasmosis is caused by <jats:italic><jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>oxoplasma gondii<\/jats:italic>. The incidence of death due to congenital toxoplasmosis in <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apan from 1974 to 2007 was calculated using the autopsy database of the <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apanese <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ociety of <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>athology and vital statistics from the <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>inistry of <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ealth, <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>abour and <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>elfare. Two neonatal deaths due to congenital toxoplasmosis were reported during that time. As there were 161\u2009195 neonatal deaths during this period and 32\u2009465 autopsies were performed, the yearly neonatal death from congenital toxoplasmosis was calculated as 2 \u00d7 161\u2009195\/32\u2009465\/34 = 0.29 and the autopsy rate as 32\u2009465\/161\u2009195 = 0.2014 (20.14%). The calculated number of annual deaths in infants was 0.82 and in children aged 1\u20134 years it was 2.09; thus, although few, deaths from congenital toxoplasmosis do still occur in neonates, infants, and young children. Therefore, obstetricians and pediatricians should be aware of the potential for congenital toxoplasmosis, and pregnant women should make every effort to avoid <jats:italic><jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>.\u2009gondii<\/jats:italic> infection.<\/jats:p>","DOI":"10.1111\/ped.12386","type":"journal-article","created":{"date-parts":[[2014,9,24]],"date-time":"2014-09-24T06:25:25Z","timestamp":1411539925000},"page":"637-639","source":"Crossref","is-referenced-by-count":5,"title":["Incidence of death from congenital toxoplasmosis in 0\u20134\u2010year\u2010old children in <scp>J<\/scp>apan"],"prefix":"10.1111","volume":"56","author":[{"given":"Tatsuji","family":"Hoshino","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Kobe City Medical Center General Hospital  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masato","family":"Kita","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kobe City Medical Center General Hospital  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiro","family":"Imai","sequence":"additional","affiliation":[{"name":"Division of Clinical Pathology Kobe City Medical Center General Hospital  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaru","family":"Yamakawa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kobe City Medical Center General Hospital  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,24]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"Centers for Disease Control and Prevention.Parasites \u2013 Toxoplasmosis (Toxoplasma infection). [Cited 2 January 2013.] Available from URL:http:\/\/www.cdc.gov\/parasites\/toxoplasmosis\/disease.html."},{"key":"e_1_2_5_3_1","volume-title":"Toxoplasmosis in Japan","author":"Yano A","year":"2007"},{"key":"e_1_2_5_4_1","first-page":"136","volume-title":"Mother\u2010to\u2010Child Transmission of Infectious Agents","author":"Kojima T","year":"2011"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3182897c36"},{"key":"e_1_2_5_6_1","unstructured":"Japanese Society of Pathology.The autopsy database of the Japanese Society of Pathology. [Cited 1 September 2010.] Available from URL:http:\/\/jsp.umin.ac.jp\/public\/autopsy\/index.html."},{"key":"e_1_2_5_7_1","first-page":"241","article-title":"A case of congenital toxoplasmosis stillbirth at autopsy and the incidence of congenital toxoplasmosis stillbirth in Japan calculated from the autopsy database of the Japanese Society of Pathology and vital statistics from the Ministry of Health, Labour and Welfare","volume":"62","author":"Hoshino T","year":"2010","journal-title":"Adv. Obstet. Gynecol."},{"key":"e_1_2_5_8_1","unstructured":"Statistics and Information Department Minister's Secretariat Ministry of Health Labour and Welfare Japan.Vital Statistics. [Cited 31 December 2012.] Available from URL:http:\/\/www.mhlw.go.jp\/english\/database\/db\u2010hw\/."},{"key":"e_1_2_5_9_1","first-page":"N132","article-title":"Management and treatment of TORCH syndrome and toxoplasmosis infection","volume":"60","author":"Yamada H","year":"2008","journal-title":"Acta Obstet. Gynaecol. Jpn"},{"key":"e_1_2_5_10_1","first-page":"461","article-title":"Congenital toxoplasmosis","volume":"67","author":"Yano A","year":"2004","journal-title":"J. Pediatr. 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