{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T01:07:07Z","timestamp":1724980027402},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,10,22]],"date-time":"2014-10-22T00:00:00Z","timestamp":1413936000000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ubin\u2013<jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>ohnson syndrome (<jats:styled-content style=\"fixed-case\">DJS<\/jats:styled-content>) is an autosomal recessive inherited disorder characterized by conjugated hyperbilirubinemia. Neonatal\u2010onset <jats:styled-content style=\"fixed-case\">DJS<\/jats:styled-content> is rare. It is caused by dysfunction of adenosine triphosphate\u2010binding cassette, sub\u2010family <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>, member 2 (<jats:styled-content style=\"fixed-case\">ABCC2<\/jats:styled-content>). We found a novel compound heterozygous mutation of <jats:styled-content style=\"fixed-case\">DJS<\/jats:styled-content>\u2010related gene: <jats:styled-content style=\"fixed-case\">W709R<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">T2145C<\/jats:styled-content>): a missense mutation in exon 17, and <jats:styled-content style=\"fixed-case\">R768W<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">C2302T<\/jats:styled-content>), a missense mutation in exon 18. Serum diglucuronosyl bilirubin\/monoglucuronosyl bilirubin ratio was high. <jats:styled-content style=\"fixed-case\">ABCC2<\/jats:styled-content> may excrete diglucuronosyl bilirubin preferentially over monoglucuronosyl bilirubin.<\/jats:p>","DOI":"10.1111\/ped.12404","type":"journal-article","created":{"date-parts":[[2014,10,22]],"date-time":"2014-10-22T06:49:30Z","timestamp":1413960570000},"source":"Crossref","is-referenced-by-count":8,"title":["Neonatal <scp>D<\/scp>ubin\u2013<scp>J<\/scp>ohnson syndrome: Novel compound heterozygous mutation in the <scp><i>ABCC2<\/i><\/scp> gene"],"prefix":"10.1111","volume":"56","author":[{"given":"Hitoshi","family":"Okada","sequence":"first","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Kagawa University  Kagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Kusaka","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Kagawa University  Kagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Fuke","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Kagawa University  Kagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Kunikata","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Kagawa University  Kagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonoko","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Kagawa University  Kagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Iwase","sequence":"additional","affiliation":[{"name":"Maternal Perinatal Center Faculty of Medicine Kagawa University  Kagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wang","family":"Nan","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacokinetics Graduate School of Pharmaceutical Sciences Kyushu University  Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Hirota","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacokinetics Graduate School of Pharmaceutical Sciences Kyushu University  Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Ieiri","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacokinetics Graduate School of Pharmaceutical Sciences Kyushu University  Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susumu","family":"Itoh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Kagawa University  Kagawa 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