{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T06:54:55Z","timestamp":1792479295135,"version":"4.5.0"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,9,24]],"date-time":"2014-09-24T00:00:00Z","timestamp":1411516800000},"content-version":"vor","delay-in-days":54,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2014,8]]},"abstract":"Abstract<\/jats:title>\n \n The aim of this systematic review was to critically examine the existing literature regarding the effectiveness of tongue\u2010tie division in infants with ankyloglossia, using the new grades of recommendations, assessment, development, and evaluation (\n GRADE<\/jats:styled-content>\n ) rating system. A clinical question was structured according to patient, intervention, comparison, and outcome, as follows: in infants with poor breast\u2010feeding and ankyloglossia (patient), does frenotomy (intervention), compared to lactation support alone (comparison), improve feeding (outcome)? An electronic literature search was systematically conducted from databases including\n P<\/jats:styled-content>\n ub\n M<\/jats:styled-content>\n ed,\n J<\/jats:styled-content>\n apana\n C<\/jats:styled-content>\n entra\n R<\/jats:styled-content>\n evuo\n M<\/jats:styled-content>\n edicina (\n I<\/jats:styled-content>\n gaku\n C<\/jats:styled-content>\n huo\n Z<\/jats:styled-content>\n asshi),\n CINAHL<\/jats:styled-content>\n , and\n C<\/jats:styled-content>\n ochrane\n L<\/jats:styled-content>\n ibrary using the key words \u201cankyloglossia,\u201d \u201ctongue\u2010tie,\u201d \u201cfrenotomy,\u201d and\/or \u201cbreast\u2010feeding\u201d in\n E<\/jats:styled-content>\n nglish and equivalent terms in\n J<\/jats:styled-content>\n apanese. The literature search yielded four randomized clinical trials, and 12 observational studies for analysis. The quality of the literature was rated in regard to the two most important outcomes (sucking\/latching, and nipple pain) and five less important outcomes (milk supply\/milk production, continuation of breast\u2010feeding, weight gain, adverse events, and dyad distress) in accordance with the\n GRADE<\/jats:styled-content>\n system. Evidence levels of the most important outcomes were rated either\n A<\/jats:styled-content>\n (strong evidence) or\n B<\/jats:styled-content>\n (moderate evidence), and less important outcomes were rated\n C<\/jats:styled-content>\n (weak evidence); every outcome consistently showed a favorable effect of frenotomy on breast\u2010feeding. The literature review supported an overall moderate quality of evidence for the effectiveness of frenotomy for the treatment of breast\u2010feeding difficulties in infants with ankyloglossia. No major complications from frenotomy were reported.\n <\/jats:p>","DOI":"10.1111\/ped.12429","type":"journal-article","created":{"date-parts":[[2014,6,30]],"date-time":"2014-06-30T22:53:35Z","timestamp":1404168815000},"page":"497-505","source":"Crossref","is-referenced-by-count":36,"title":["Does frenotomy improve breast\u2010feeding difficulties in infants with ankyloglossia?"],"prefix":"10.1111","volume":"56","author":[{"given":"Yasuo","family":"Ito","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Pediatric Surgery International University of Health and Welfare Atami Hospital Atami Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/089033449000600315"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2006.01.004"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(00)00359-1"},{"key":"e_1_2_6_5_1","first-page":"520","article-title":"Survey on operative treatment in ankyloglossia and its results","volume":"105","author":"Committee of Ethics, Japan Pediatric Society","year":"2001","journal-title":"J. Jpn Pediatr. Soc."},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2005.00604.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2006.05.024"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-0077"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2011.0030"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39489.470347.AD"},{"key":"e_1_2_6_11_1","unstructured":"Sch\u00fcnemannH BroekJ OxmanA eds.GRADE handbook for grading the quality of evidence and the strength of recommendations. Version 3.2 updated March2009. [Cited 19 April 2013.] Available from URL:http:\/\/www.who.int\/hiv\/topics\/mtct\/grade_handbook.pdf."},{"key":"e_1_2_6_12_1","unstructured":"The Cochrane Collaboration.Cochrane handbook for systematic review of interventions. Version 5.1.0 2011. [Cited 19 April 2013.] Available from URL:http:\/\/handbook.cochrane.org\/."},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/089033449601200321"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.110.5.e63"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0890334404266976"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2005.00603.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2006.1.216"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2553"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1234041"},{"key":"e_1_2_6_20_1","first-page":"395","article-title":"\u201cIt's on the tip of my tongue\u201d evaluation of a new frenulotomy service in Northern England","volume":"19","author":"Finigan V","year":"2009","journal-title":"MIDIRS Midwifery Dig."},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjom.2009.17.4.41671"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2010.04.003"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2011.02278.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2012.05.009"},{"key":"e_1_2_6_25_1","unstructured":"National Institute for Health and Care Excellence.Interventional procedure guidance 149. Division of ankyloglossia (tongue\u2010tie) for breast feeding. [Cited 19 April 2013.] Available from URL:http:\/\/publications.nice.org.uk\/division\u2010of\u2010ankyloglossia\u2010tongue\u2010tie\u2010for\u2010breastfeeding\u2010ipg149\/the\u2010procedure#indications."},{"key":"e_1_2_6_26_1","unstructured":"Academy of Breastfeeding Medicine Protocol Committee.(Chairperson: Ballard J). Protocol 11: Guidelines for the evaluation and management of neonatal ankyloglossia and its complications in the breastfeeding dyad. [Cited 19 April 2013.] Available from URL:http:\/\/www.bfmed.org\/Media\/Files\/Protocols\/ankyloglossia.pdf."},{"key":"e_1_2_6_27_1","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1093\/pch\/16.4.222","article-title":"Position statement: Ankyloglossia and breastfeeding","volume":"16","author":"Rowan\u2010Legg A","year":"2011","journal-title":"Paediatr. 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[Cited 7 May 2013.] Available from URL:http:\/\/www.aapd.org\/search\/?Keywords=Ankyloglossia."}],"container-title":["Pediatrics International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.12429","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.12429","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T07:23:20Z","timestamp":1695972200000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ped.12429"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["10.1111\/ped.12429"],"URL":"https:\/\/doi.org\/10.1111\/ped.12429","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.727746087.793533642","asserted-by":"object"}]},"ISSN":["1328-8067","1442-200X"],"issn-type":[{"value":"1328-8067","type":"print"},{"value":"1442-200X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8]]}}}