{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T10:27:23Z","timestamp":1774952843409,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,4,13]],"date-time":"2015-04-13T00:00:00Z","timestamp":1428883200000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Diffuse neonatal hemangiomatosis (<jats:styled-content style=\"fixed-case\">DNH<\/jats:styled-content>) is a rare condition characterized by the concomitant development of multiple cutaneous infantile hemangiomas (<jats:styled-content style=\"fixed-case\">IH<\/jats:styled-content>) and visceral hemangiomas. Recently, an association between erythropoietin treatment and an increased incidence of infantile hemangioma was noted. A <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apanese male infant was born via cesarean section at 27\u2009weeks of gestation. Following the commencement of erythropoietin treatment for anemia of prematurity, he developed multiple cutaneous hemangiomas, high cardiac output heart failure and hepatomegaly. Abdominal imaging indicated comorbidity of diffuse infantile hepatic hemanigomas, resulting in the final diagnosis of <jats:styled-content style=\"fixed-case\">DNH<\/jats:styled-content>. The discontinuation of erythropoietin treatment and long\u2010term therapy with propranolol improved the hepatic lesions and cutaneous hemangiomas. The possibility of multiple organ involvement and the exacerbating effects of erythropoietin treatment should be considered in cases in which multiple cutaneous hemangiomas develop in preterm infants receiving erythropoietin treatment.<\/jats:p>","DOI":"10.1111\/ped.12517","type":"journal-article","created":{"date-parts":[[2015,4,14]],"date-time":"2015-04-14T02:58:05Z","timestamp":1428980285000},"source":"Crossref","is-referenced-by-count":6,"title":["Diffuse neonatal hemangiomatosis in a very low\u2010birthweight infant treated with erythropoietin"],"prefix":"10.1111","volume":"57","author":[{"given":"Takashi","family":"Okuno","sequence":"first","affiliation":[{"name":"Department of Pediatrics Faculty of Medical Sciences University of Fukui  Fukui Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuko","family":"Tokuriki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medical Sciences University of Fukui  Fukui Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomomi","family":"Yoshino","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medical Sciences University of Fukui  Fukui Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanae","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medical Sciences University of Fukui  Fukui Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4488-0308","authenticated-orcid":false,"given":"Yusei","family":"Ohshima","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medical Sciences University of Fukui  Fukui Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,13]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.12184"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.04.003"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2010.187344"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2007.08.009"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2011.10.037"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-3458"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2767"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2013.07.049"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12192"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.2478\/v10039-012-0071-1"}],"container-title":["Pediatrics International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.12517","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.12517","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T09:59:16Z","timestamp":1695981556000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ped.12517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/ped.12517"],"URL":"https:\/\/doi.org\/10.1111\/ped.12517","archive":["Portico"],"relation":{},"ISSN":["1328-8067","1442-200X"],"issn-type":[{"value":"1328-8067","type":"print"},{"value":"1442-200X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4]]}}}