{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T22:35:25Z","timestamp":1788820525993,"version":"build-2803163510"},"reference-count":44,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T00:00:00Z","timestamp":1445299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Brucellosis produces a variety of non\u2010specific hematological abnormalities. The aim of the present study was to evaluate the hematological findings in childhood brucellosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records of children with brucellosis admitted to a tertiary hospital in a 1\u2009year period, were analyzed retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010nine patients (mean age, 14.5\u2009\u00b1\u20093.3\u2009years) were diagnosed with brucellosis. The most common hematological finding was thrombocytopenia (n\u2009=\u200911, 15.9%). Thrombocytosis was detected in five patients (7.3%), leukopenia in four (5.8%), anemia in three (4.3%), and bicytopenia in three (4.3%). None of the patients had pancytopenia. Blood culture was positive for<jats:italic>Brucella<\/jats:italic>spp. in 41 patients (59.4%). Among those patients with positive blood culture, six (14.6%) had serum agglutination test titer \u22641\/80. Platelet (PLT) count was significantly lower in the bacteremia\u2010positive group. The OR (95%CI) of bacteremia for PLT cut\u2010off 200 000\/mm<jats:sup>3<\/jats:sup>was 0.148 (95%CI: 0.031\u20130.718) and relative risk was 1.718 (95%CI: 1.244\u20132.372;<jats:italic>P\u2009=<\/jats:italic>\u20090.010).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Brucellosis should be kept in mind in the differential diagnosis of isolated thrombocytopenia in pediatric patients from endemic areas.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.12688","type":"journal-article","created":{"date-parts":[[2015,5,16]],"date-time":"2015-05-16T04:41:05Z","timestamp":1431751265000},"page":"1108-1111","source":"Crossref","is-referenced-by-count":12,"title":["Hematological findings in children with brucellosis"],"prefix":"10.1111","volume":"57","author":[{"given":"Adalet","family":"Aypak","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cenk","family":"Aypak","sequence":"additional","affiliation":[{"name":"Department of Family Medicine Van Geva\u015f State Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasemin","family":"Bayram","sequence":"additional","affiliation":[{"name":"Microbiology Laboratory Van Training and Research Hospital Van Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,10,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra050570"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1258\/004947505774938693"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2008.02661.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.7883\/yoken.JJID.2006.160","article-title":"Presentation of childhood brucellosis in Western Greece","volume":"59","author":"Giannakopoulos I","year":"2006","journal-title":"Jpn. 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