{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T13:56:19Z","timestamp":1760622979076},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,10,28]],"date-time":"2015-10-28T00:00:00Z","timestamp":1445990400000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report the case of a 9\u2010year\u2010old girl with Down syndrome (DS) diagnosed with idiopathic pulmonary hemosiderosis (IPH). Although acute pneumonia complicated by hemolytic anemia was suspected, IPH was finally diagnosed on bronchoscopy. Treatment with prednisolone achieved good clinical response. An association between IPH and DS was not able to be identified, but immunological issues in DS may contribute to the onset of IPH. Recurrent and intractable respiratory symptoms with marked infiltrative shadows in the bilateral lungs and complicated by severe anemia in patients with DS should suggest IPH.<\/jats:p>","DOI":"10.1111\/ped.12690","type":"journal-article","created":{"date-parts":[[2015,10,28]],"date-time":"2015-10-28T08:19:53Z","timestamp":1446020393000},"page":"1009-1012","source":"Crossref","is-referenced-by-count":15,"title":["Idiopathic pulmonary hemosiderosis complicated by Down syndrome"],"prefix":"10.1111","volume":"57","author":[{"given":"Hirofumi","family":"Watanabe","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Child Health Nihon University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamoru","family":"Ayusawa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health Nihon University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masataka","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health Nihon University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ami","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health Nihon University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Komori","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health Nihon University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuriko","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health Nihon University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaharu","family":"Matsumura","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health Nihon University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Kamiyama","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health Nihon University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Izumi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health Nihon University School of Medicine  Tokyo Japan"},{"name":"Itabashi Medical Association Hospital  Itabashi Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shori","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health Nihon University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,10,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01958645"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.116.3.721"},{"key":"e_1_2_5_4_1","first-page":"58","article-title":"Idiopathic pulmonary haemosiderosis in a child with Down's syndrome: Case report and review of the literature","volume":"29","author":"Aceti A","year":"2012","journal-title":"Sarcoidosis Vasc. Diffuse Lung Dis."},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2007\/150926"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21357"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2005.11.003"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-8-161"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320460408"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2011.04335.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1590\/0103-0582201432218913"},{"key":"e_1_2_5_12_1","unstructured":"SatoY NagamatsuI SaekiY et al.A case report of Idiopathic pulmonary haemosiderosis in a child with Down syndrome (Japanese only)."},{"key":"e_1_2_5_13_1","first-page":"1749","article-title":"Two Cases of Idiopathic Pulmonary Hemosiderosis: Analysis of Chest CT Findings","volume":"30","author":"Akio N","year":"1992","journal-title":"Nihon Kyobu Shikkan Gakkai Zasshi"},{"key":"e_1_2_5_14_1","first-page":"580","article-title":"A case of Down syndrome complicated with idiopathic pulmonary hemosiderosis","volume":"49","author":"Taruhisa K","year":"1995","journal-title":"Iryo"}],"container-title":["Pediatrics International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.12690","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.12690","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.12690","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T12:09:55Z","timestamp":1696162195000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ped.12690"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1111\/ped.12690"],"URL":"https:\/\/doi.org\/10.1111\/ped.12690","archive":["Portico"],"relation":{},"ISSN":["1328-8067","1442-200X"],"issn-type":[{"value":"1328-8067","type":"print"},{"value":"1442-200X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10]]}}}