{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T12:57:48Z","timestamp":1789390668873,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,9,21]],"date-time":"2015-09-21T00:00:00Z","timestamp":1442793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Laryngomalacia (LM) is the most common congenital anomaly of larynx that causes stridor in children. We evaluated the efficacy of epiglottic suture and laser epiglottopexy for treatment of infants with severe LM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Surgical intervention was performed in 19 patients with severe LM, after the diagnosis was established using flexible laryngotracheobronchoscopy. Five patients had isolated type 1 LM, and 14 patients had a combination of type 1 and 3 LM. Indication for surgical treatment was the presence of LM with at least one of the following: malnutrition (body mass index [BMI] Z score\u2009&lt;\u2009\u20132\u2009SD), dysphagia or symptoms of gastroesophageal reflux and mean oxygen saturation (SaO<jats:sub>2<\/jats:sub>) &lt;92% with oxygen desaturation index (ODI)\u2009&gt;\u20093.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Epiglottic suture was performed in 11 patients, and laser epiglottopexy in eight, at mean age 3.95\u2009\u00b1\u20092.4\u2009months. Rate of operation was 2.2\u2010fold greater for more severe anomaly (combination of type 1 and 3 LM) than for isolated type 1. At 6\u2009month follow up symptoms had gradually improved, as well as nutritional status, with increase of mean BMI Z score from \u20133.7 to \u20130.9 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). Mean preoperative SaO<jats:sub>2<\/jats:sub> was 89.4\u2009\u00b1\u20094.3% with mean ODI of 5.8. At 6\u2009month follow up, mean SaO<jats:sub>2<\/jats:sub> was 96.7\u2009\u00b1\u20091.1%, and mean ODI was 1.2 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Epiglottic suture and laser epiglottopexy are efficient surgical techniques that lead to significant improvement of symptoms, oxygenation and nutritional status in patients with LM.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.12706","type":"journal-article","created":{"date-parts":[[2015,5,22]],"date-time":"2015-05-22T02:45:24Z","timestamp":1432262724000},"page":"1159-1163","source":"Crossref","is-referenced-by-count":9,"title":["Surgical treatment of severe laryngomalacia: Six\u2009month follow up"],"prefix":"10.1111","volume":"57","author":[{"given":"Ivan","family":"Baljosevic","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u201cDr Vukan Cupic\u201d Mother and Child Health Institute of Serbia  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Predrag","family":"Minic","sequence":"additional","affiliation":[{"name":"Department of Pulmonology \u201cDr Vukan Cupic\u201d Mother and Child Health Institute of Serbia  Belgrade Serbia"},{"name":"School of Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goran","family":"Trajkovic","sequence":"additional","affiliation":[{"name":"School of Medicine University of Belgrade  Belgrade Serbia"},{"name":"Institute for Medical Statistics  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordana","family":"Markovic\u2010Sovtic","sequence":"additional","affiliation":[{"name":"Clinic for Pediatrics \u201cDr Vukan Cupic\u201d Mother and Child Health Institute of Serbia  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bojana","family":"Radojicic","sequence":"additional","affiliation":[{"name":"Clinic for Pediatrics \u201cDr Vukan Cupic\u201d Mother and Child Health Institute of Serbia  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandar","family":"Sovtic","sequence":"additional","affiliation":[{"name":"Department of Pulmonology \u201cDr Vukan Cupic\u201d Mother and Child Health Institute of Serbia  Belgrade Serbia"},{"name":"School of Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,9,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1996.01890240123028"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-72992005000300011"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199911000-00009"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-005-2568-6"},{"key":"e_1_2_6_6_1","unstructured":"World Health Organization. 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