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In the ALB\u2010NHL03 study, the 5\u2009year EFS according to clinical stage in patients with lymphoblastic T\u2010cell lymphoma (T\u2010LBL) was 70.6% for stage III and 88.9% for stage IV. In mature B\u2010cell lymphoma, the B\u2010NHL03 study indicated that the 4\u2009year EFS according to treatment group was 94% for group 1, 98% for group 2, 84% for group 3, and 78% for group 4. Moreover, the 2\u2009year EFS rate was 81% in Japanese advanced stage patients based on the international ALCL99 study. Thus, EFS &gt;80% was achieved in any subtype of pediatric lymphoma. With regard to refractory or recurrent lymphoma, however, treatment methods for improvement of the survival rate in these patients still need to be developed. Also the difference between child, and adolescent and young adult patients still needs to be clarified, and treatment protocols developed. Although lymphoma treatment does not greatly change according to country, it does differ between other countries and Japan for some subtypes of lymphoma. In particular, the results of treatment of stage III T\u2010LBL in Japan are worse than those in the USA and Europe. The priority in future studies will be to collect data on these differences, and the reasons for these differences.<\/jats:p>","DOI":"10.1111\/ped.12725","type":"journal-article","created":{"date-parts":[[2015,6,19]],"date-time":"2015-06-19T13:59:56Z","timestamp":1434722396000},"page":"523-534","source":"Crossref","is-referenced-by-count":11,"title":["Treatment of pediatric lymphoma in Japan: Current status and plans for the future"],"prefix":"10.1111","volume":"57","author":[{"given":"Ryoji","family":"Kobayashi","sequence":"first","affiliation":[{"name":"Department of Pediatrics Sapporo Hokuyu Hospital  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shosuke","family":"Sunami","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Narita Red Cross Hospital  Narita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuo","family":"Mitsui","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Yamagata University School of Medicine  Yamagata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsuko","family":"Nakazawa","sequence":"additional","affiliation":[{"name":"Department of Pathology, Children's Cancer Cente National Center for Child Health and Development  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhki","family":"Koga","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kyushu University Graduate School of Medicine  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kobe University School of Medicine  Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiko","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Saiseikai Yokohamashi Nanbu Hospital  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun\u2010ichi","family":"Ueyama","sequence":"additional","affiliation":[{"name":"Department of Multidisciplinary Internal Medicine, Division of Pediatrics and Perinatology Tottori University Faculty of Medicine  Yonago Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoo","family":"Osumi","sequence":"additional","affiliation":[{"name":"Division of Leukemia and Lymphoma, Children's Cancer Center National Center for Child Health and Development  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reiji","family":"Fukano","sequence":"additional","affiliation":[{"name":"Department of Pediatrics National Hospital Organization Kyusyu Cancer Center  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Ohki","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology Gunma Children's Medical Center  Shibukawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Sekimizu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics National Hospital Organization Nagoya Medical Center  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Pediatrics St. Marianna University School of Medicine  Kawasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Lymphoma Committee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Japanese Pediatric Leukemia\/Lymphoma Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,8,28]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"462","article-title":"Disease Registration Committee, Japanese Society of Pediatric Hematology and Oncology. 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