{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T13:08:36Z","timestamp":1754399316198},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,10,28]],"date-time":"2015-10-28T00:00:00Z","timestamp":1445990400000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Peripheral T\u2010cell lymphoma (PTCL) is rare in children, and it has a poor prognosis compared with other types of lymphoma. We report the case of a 7\u2010year\u2010old boy with spontaneous improvement of PTCL complicated by hemophagocytic syndrome as the initial symptom. He complained of pain and swelling of the right neck and presented with high fever. Pancytopenia, liver dysfunction, elevated ferritin and soluble interleukin 2 receptor were noted on laboratory tests. Peripheral blood plasma and white blood cells were positive for Epstein\u2013Barr virus (EBV) genome but, after several days, the fever abated and laboratory data improved. On histopathology of lymph node biopsy, he was diagnosed as having PTCL not otherwise specified (PTCL\u2010NOS) with EBV infection. He received no chemotherapy and was disease free at the last follow up, 6\u2009years 8\u2009months after onset. This is probably the first case of spontaneous improvement in PTCL\u2010NOS. Careful treatment planning is therefore necessary in PTCL\u2010NOS, given the possibility of spontaneous improvement of symptoms.<\/jats:p>","DOI":"10.1111\/ped.12784","type":"journal-article","created":{"date-parts":[[2015,10,28]],"date-time":"2015-10-28T08:19:53Z","timestamp":1446020393000},"page":"1035-1037","source":"Crossref","is-referenced-by-count":4,"title":["Spontaneous improvement in a pediatric patient with peripheral T\u2010cell lymphoma"],"prefix":"10.1111","volume":"57","author":[{"given":"Ryoji","family":"Kobayashi","sequence":"first","affiliation":[{"name":"Department of Pediatrics Sapporo Hokuyu Hospital  Shiroishiku Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Sapporo Hokuyu Hospital  Shiroishiku Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daiki","family":"Hori","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Sapporo Hokuyu Hospital  Shiroishiku Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Kishimoto","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Sapporo Hokuyu Hospital  Shiroishiku Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirozumi","family":"Sano","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Sapporo Hokuyu Hospital  Shiroishiku Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsuko","family":"Nakazawa","sequence":"additional","affiliation":[{"name":"Department of Pathology National Center for Child Health and Development  Setagaya Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazue","family":"Yasuda","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Sapporo Hokuyu Hospital  Shiroishiku Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunihiko","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Sapporo Hokuyu Hospital  Shiroishiku Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,10,28]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.16.4558"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-008-1002-y"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21293"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21543"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e31817e4b25"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e31817588e8"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.22329"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-5710(97)00584-7"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428190701713630"}],"container-title":["Pediatrics International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.12784","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.12784","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.12784","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T12:10:36Z","timestamp":1696162236000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ped.12784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1111\/ped.12784"],"URL":"https:\/\/doi.org\/10.1111\/ped.12784","archive":["Portico"],"relation":{},"ISSN":["1328-8067","1442-200X"],"issn-type":[{"value":"1328-8067","type":"print"},{"value":"1442-200X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10]]}}}