{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T06:53:47Z","timestamp":1725173627595},"reference-count":11,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T00:00:00Z","timestamp":1471910400000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Kawasaki disease (KD) is an acute febrile illness of childhood characterized by systemic vasculitis, especially coronary arteritis. Aortic valve regurgitation (AVR) is a relatively common complication. There have been no reports to date of heart failure and left ventricular non\u2010compaction (LVNC) after acute KD, although the precise etiology of this condition remains unclear. A 6\u2010month\u2010old boy with KD was admitted to hospital. Despite high\u2010dose i.v. gammaglobulin for dilation of the coronary artery, moderate AVR appeared, and thereafter he developed heart failure. A rough, dense LV myocardium indicated LVNC. On genetic testing a heterogenous 163G &gt; A substitution changing a valine to isoleucine in <jats:italic>LIM domain binding protein 3<\/jats:italic> (<jats:italic>LDB3<\/jats:italic>) was identified. Additional cardiac stress, such as that caused by AVR and\/or KD might have triggered cardiac failure in the form of LVNC due to <jats:italic>LDB3<\/jats:italic> mutation.<\/jats:p>","DOI":"10.1111\/ped.12983","type":"journal-article","created":{"date-parts":[[2016,8,24]],"date-time":"2016-08-24T02:50:49Z","timestamp":1472007049000},"page":"797-800","source":"Crossref","is-referenced-by-count":4,"title":["Left ventricular non\u2010compaction revealed by aortic regurgitation due to Kawasaki disease in a boy with <i>LDB3<\/i> mutation"],"prefix":"10.1111","volume":"58","author":[{"given":"Akira","family":"Hachiya","sequence":"first","affiliation":[{"name":"Department of Pediatrics Shinshu University School of Medicine  Matsumoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Motoki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Shinshu University School of Medicine  Matsumoto 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