{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T04:44:24Z","timestamp":1789447464103,"version":"build-2803163510"},"reference-count":10,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2016,11,23]],"date-time":"2016-11-23T00:00:00Z","timestamp":1479859200000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2016,11]]},"abstract":"Abstract<\/jats:title>Pseudohypoparathyroidism type 1b (PHP<\/jats:styled-content>\u20101b) is usually diagnosed on various symptoms of hypocalcemia. Previous studies reported a few cases of autosomal dominant pattern PHP<\/jats:styled-content>\u20101b identified on familial analysis with asymptomatic hypocalcemia. Herein we report the case of a 6\u2010year\u2010old male patient with sporadic PHP<\/jats:styled-content>\u20101b incidentally detected on preoperative examination. He had neither characteristic findings of Albright hereditary osteodystrophy nor evidence of tetany. Sporadic PHP<\/jats:styled-content>\u20101b was diagnosed on the basis of clinical observation and laboratory examination. In addition, genetic testing using methylation\u2010specific multiplex ligation\u2010dependent probe amplification indicated broad methylation abnormalities and confirmed the sporadic form of PHP<\/jats:styled-content>\u20101b. Sporadic PHP<\/jats:styled-content>\u20101b might often be overlooked when diagnosis is done simply on definitive clinical features. To avoid this, DNA<\/jats:styled-content> sequencing and methylation analysis should be performed even in the absence of definitive clinical features.<\/jats:p>","DOI":"10.1111\/ped.13096","type":"journal-article","created":{"date-parts":[[2016,11,23]],"date-time":"2016-11-23T05:36:17Z","timestamp":1479879377000},"page":"1229-1231","source":"Crossref","is-referenced-by-count":5,"title":["Sporadic pseudohypoparathyroidism type\u20101b with asymptomatic hypocalcemia"],"prefix":"10.1111","volume":"58","author":[{"given":"Motohide","family":"Goto","sequence":"first","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Occupational and Environmental Health Kitakyushu City Fukuoka Japan"},{"name":"Health Care & Support Center General Affairs and Human Resources Office Ube Industries Ube City Yamaguchi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiyo","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Occupational and Environmental Health Kitakyushu City Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Occupational and Environmental Health Kitakyushu City Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akie","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Molecular Endocrinology National Research Institute for Child Health and Development Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichiro","family":"Sano","sequence":"additional","affiliation":[{"name":"Department of Molecular Endocrinology National Research Institute for Child Health and Development Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayo","family":"Kagami","sequence":"additional","affiliation":[{"name":"Department of Molecular Endocrinology National Research Institute for Child Health and Development Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maki","family":"Fukami","sequence":"additional","affiliation":[{"name":"Department of Molecular Endocrinology National Research Institute for Child Health and Development Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reiko","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Occupational and Environmental Health Kitakyushu City Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsuke","family":"Araki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Occupational and Environmental Health Kitakyushu City Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuyasu","family":"Kubo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Occupational and Environmental Health Kitakyushu City Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rinko","family":"Kawagoe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Occupational and Environmental Health Kitakyushu City Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasusada","family":"Kawada","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Occupational and Environmental Health Kitakyushu City Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Kusuhara","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Occupational and Environmental Health Kitakyushu City Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026510200264"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.K10E-364"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0176"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1203\/01.PDR.0000059752.07086.A2"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ12-0257"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2010.081356"},{"key":"e_1_2_7_8_1","first-page":"619","volume-title":"Pediatric Endocrinology and Inborn Errors of Metabolism","author":"Roth KS","year":"2009"},{"key":"e_1_2_7_9_1","first-page":"2349","article-title":"A case of pseudohypoparathyroidism in early childhood","volume":"51","author":"Tajima G","year":"1998","journal-title":"Jpn. J. Pediatr."},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-10-0795"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1086\/429932"}],"container-title":["Pediatrics International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.13096","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.13096","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.13096","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T12:54:21Z","timestamp":1694696061000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ped.13096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1111\/ped.13096"],"URL":"https:\/\/doi.org\/10.1111\/ped.13096","archive":["Portico"],"relation":{},"ISSN":["1328-8067","1442-200X"],"issn-type":[{"value":"1328-8067","type":"print"},{"value":"1442-200X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11]]}}}