{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T18:31:35Z","timestamp":1700418695925},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,11,6]],"date-time":"2016-11-06T00:00:00Z","timestamp":1478390400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>While the association between scoliosis and cardiac and respiratory function impairments has been well characterized in clinical practice and research, the potential effect of scoliosis on urinary tract structure and renal function has received little attention. Therefore, the purpose of this study was to evaluate the preoperative clinical characteristics of urinary tract structure and renal function in pediatric patients with idiopathic scoliosis, using a combination of blood tests, urinalysis, and imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Preoperative measures of urinary tract structure and renal function were obtained for 16 patients, 13\u201317 years old, scheduled for corrective surgery for idiopathic scoliosis. Preoperative assessment included blood test and urinalysis, combined with structural imaging on ultrasound (<jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>), magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>), magnetic resonance urography (<jats:styled-content style=\"fixed-case\">MRU<\/jats:styled-content>), and radioisotope tracing (<jats:styled-content style=\"fixed-case\">RI<\/jats:styled-content>), using technetium\u201099 <jats:italic>m<\/jats:italic> mercaptoacetyltriglycine (<jats:sup>99m<\/jats:sup>Tc\u2010<jats:styled-content style=\"fixed-case\">MAG<\/jats:styled-content>3). Differences in blood and urine tests between patients with and without urinary tract obstruction (<jats:styled-content style=\"fixed-case\">UTO<\/jats:styled-content>) were evaluated for significance using Mann\u2010Whitney U test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For all 16 patients, blood tests and <jats:styled-content style=\"fixed-case\">MRU<\/jats:styled-content> were within normal limits. Dilatation of the renal pelvis was identified on <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> in eight patients (50.0%). <jats:styled-content style=\"fixed-case\">UTO<\/jats:styled-content> was identified on <jats:styled-content style=\"fixed-case\">RI<\/jats:styled-content> in six patients (37.5%). <jats:styled-content style=\"fixed-case\">UTO<\/jats:styled-content> was associated with elevated \u03b22\u2010microglobulin concentration. Urinary \u03b22\u2010microglobulin concentration &gt;0.7 \u03bcg\/mg Cr differentiated patients with <jats:styled-content style=\"fixed-case\">UTO<\/jats:styled-content> from those without <jats:styled-content style=\"fixed-case\">UTO<\/jats:styled-content>, with a sensitivity of 100% and specificity of 70%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>\u03b22\u2010Microglobulin concentration may be a useful marker to screen for asymptomatic <jats:styled-content style=\"fixed-case\">UTO<\/jats:styled-content> in patients with idiopathic scoliosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.13115","type":"journal-article","created":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T08:18:45Z","timestamp":1470817125000},"page":"48-52","source":"Crossref","is-referenced-by-count":1,"title":["Preoperative urinary tract obstruction in scoliosis patients"],"prefix":"10.1111","volume":"59","author":[{"given":"Shigeru","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Pediatrics Seirei Sakura Citizen Hospital Sakura Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiaki","family":"Kotani","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Seirei Sakura Citizen Hospital Sakura Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuetsu","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seirei Sakura Citizen Hospital Sakura Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Kawamura","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seirei Sakura Citizen Hospital Sakura Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Ohtake","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Saitama Medical University Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,11,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1748-7161-8-4"},{"key":"e_1_2_8_3_1","first-page":"193","article-title":"Adolescent idiopathic scoliosis: Diagnosis and management","volume":"89","author":"Horme JP","year":"2014","journal-title":"Am. Fam. Physician"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199506000-00008"},{"key":"e_1_2_8_5_1","first-page":"1766","article-title":"Lung thoracic compliance in idiopathic scoliosis under general anesthesia","volume":"2","author":"Kotani T","year":"2011","journal-title":"J. Spine Res."},{"key":"e_1_2_8_6_1","first-page":"929","article-title":"Associated anomalies of congenital scoliosis","volume":"7","author":"Shimode M","year":"1982","journal-title":"Orthop. Surg. Traumatol."},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.BRS.0000106490.82936.89"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.5980\/jpnjurol1928.76.7_974"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/0189-6725.99397"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2014.01.004"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-4096.2001.woodward.2578.x"},{"key":"e_1_2_8_12_1","first-page":"2214","article-title":"Utility of technetium\u201099 m\u2010MAG3 diuretic renography in the neonatal period","volume":"36","author":"Wong JCH","year":"1995","journal-title":"J. Nucl. Med."},{"key":"e_1_2_8_13_1","first-page":"725","article-title":"Value of supranormal function and renogram patterns on 99mTc\u2010mercaptoacetyltriglycine scintigraphy in relation to the extent of hydronephrosis for predicting ureteropelvic junction obstruction in the newborn","volume":"44","author":"Moon DH","year":"2003","journal-title":"J. Nucl. Med."},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)41991-4"},{"key":"e_1_2_8_15_1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3165\/jjpn.23.85","article-title":"Sonographic assessment of kidney length in Japanese children","volume":"23","author":"Kikuchi E","year":"2010","journal-title":"J Pediatr. Nephrol."},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2006.00178.x"},{"key":"e_1_2_8_17_1","first-page":"169","article-title":"Long\u2010term effect of Boston brace treatment on renal function in patients with idiopathic scoliosis","volume":"180","author":"Berg U","year":"1983","journal-title":"Clin. Orthop. Relat. Res."},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00620476"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2010.03.066"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-012-2217-6"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.07.057"}],"container-title":["Pediatrics International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.13115","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.13115","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.13115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T22:29:49Z","timestamp":1694730589000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ped.13115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,6]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1111\/ped.13115"],"URL":"https:\/\/doi.org\/10.1111\/ped.13115","archive":["Portico"],"relation":{},"ISSN":["1328-8067","1442-200X"],"issn-type":[{"value":"1328-8067","type":"print"},{"value":"1442-200X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,6]]}}}