{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:10:21Z","timestamp":1787166621813,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T00:00:00Z","timestamp":1485388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Management of congenital heart disease (\n                      <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>\n                      ) in developing countries is challenging because of limited access to health\u2010care facilities and socioeconomic limitations. The aim of this study was to describe the recent experience with\n                      <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>\n                      at Children's Hospital, Vientiane, Laos, the only pediatric referral hospital in the country.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      From July 2013 to November 2015, 1009 echocardiograms were carried out in 797 individuals who visited Children's Hospital, in whom\n                      <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>\n                      was identified in 213. Demographic characteristics, echocardiography and age at first\n                      <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>\n                      diagnosis on echocardiogram were compared by residential area.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among the 213 patients, the most frequent anomalies, in descending order, were ventricular septal defect, atrial septal defect, patent ductus arteriosus, and tetralogy of Fallot. Moderate or severe\n                      <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>\n                      requiring surgery or intervention was detected in 137 patients; median age at initial diagnosis was 6.0 months (\n                      <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>\n                      , 1.5\u201329.8). Among those with moderate or severe\n                      <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>\n                      , 89 patients were from rural areas and 48 from the capital area. The proportion of patients from rural areas older than 1 and 3 years at diagnosis was 46.1% and 32.6%, respectively. In contrast, patients from the capital area were diagnosed at a significantly earlier age: 16.7% at age &gt;1 year and 6.2% at age &gt;3 years (both\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001 vs rural areas).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Diagnosis of\n                      <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>\n                      requiring surgery is delayed in Laos, especially in rural areas. Better education and training of local medical staff, and greater access to medical advice are required to improve\n                      <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>\n                      care in Laos.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ped.13156","type":"journal-article","created":{"date-parts":[[2016,9,2]],"date-time":"2016-09-02T12:49:48Z","timestamp":1472820588000},"page":"271-279","source":"Crossref","is-referenced-by-count":10,"title":["Congenital heart disease at Laos Children's Hospital: Two year experience"],"prefix":"10.1111","volume":"59","author":[{"given":"In\u2010Chang","family":"Hwang","sequence":"first","affiliation":[{"name":"Cardiovascular Unit Vientiane Laos"},{"name":"Korea International Cooperation Agency (KOICA) Laos Office Vientiane Laos"},{"name":"Cardiovascular Center and Department of Internal Medicine Seoul National University Hospital Seoul 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