{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T19:51:45Z","timestamp":1769197905512,"version":"3.49.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,1,19]],"date-time":"2017-01-19T00:00:00Z","timestamp":1484784000000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cardiac catheterization of childhood pulmonary arterial hypertension (<jats:styled-content style=\"fixed-case\">PAH<\/jats:styled-content>) is used to assess the severity of the disease as well as prognosis, selection of the most adequate pulmonary vasodilators, and evaluation of effectiveness. Sudden deterioration of cardiovascular hemodynamics, however, can be easily induced by pain, patient agitation, catheter manipulation, and by vasodilator provocation tests; these could trigger a pulmonary hypertension crisis, vagotony, respiratory distress, and hemoptysis resulting in critical complications, including death. Those patients with New York Heart Association functional class <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content> are at an especially high risk. It is noteworthy that pulmonary arteriography is a contraindication in patients with <jats:styled-content style=\"fixed-case\">PAH<\/jats:styled-content>. In a review of 7218 adult patients, 76 (1.1%) serious complications, including four deaths, were reported; with regard to the pediatric patients, 29 (10.7%) out of 270 patients with complications, including one with cardiogenic shock requiring cardiopulmonary resuscitation in addition to minor complications, were reported. To prevent serious complications, basic and routine precautions, such as oxygen and concomitant transcutaneous oxygen saturation and electrocardiogram monitoring during transportation to and from the catheter laboratory, are mandatory. Furthermore, the cooperation of experienced physicians and well informed medical staff in addition to meticulous preparation, for example, calculation of prior doses of catecholamine and confirmation of the presence of emergency equipment, is required.<\/jats:p>","DOI":"10.1111\/ped.13161","type":"journal-article","created":{"date-parts":[[2016,9,7]],"date-time":"2016-09-07T15:10:10Z","timestamp":1473261010000},"page":"3-9","source":"Crossref","is-referenced-by-count":11,"title":["Cardiac catheterization in children with pulmonary arterial hypertension"],"prefix":"10.1111","volume":"59","author":[{"given":"Hiroyuki","family":"Matsuura","sequence":"first","affiliation":[{"name":"First Department of Pediatrics Toho University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,1,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.192230"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.04.012"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.71.1785"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.07.061"},{"key":"e_1_2_8_6_1","first-page":"545","article-title":"Assessment of safety for cardiac catheterization in patients with idiopathic pulmonary arterial hypertension","volume":"25","author":"Matsuura H","year":"2009","journal-title":"Pediatr. 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