{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:26:10Z","timestamp":1761017170710,"version":"3.37.3"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,1,19]],"date-time":"2017-01-19T00:00:00Z","timestamp":1484784000000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Opsoclonus\u2013myoclonus syndrome (<jats:styled-content style=\"fixed-case\">OMS<\/jats:styled-content>) is characterized by abnormal eye and systemic involuntary movements, as well as cerebellar ataxia. Some sedatives and anesthetics worsen movements associated with <jats:styled-content style=\"fixed-case\">OMS<\/jats:styled-content>, while there is no known report of a negative effect of atropine. We report on sedation in two patients with <jats:styled-content style=\"fixed-case\">OMS<\/jats:styled-content>. Involuntary movements were transiently worsened after using atropine with midazolam or thiamylal in both, but were not seen when atropine was not used. We speculated that atropine has the potential to exacerbate involuntary movements in <jats:styled-content style=\"fixed-case\">OMS<\/jats:styled-content> due to vulnerability to this agent via unknown mechanisms.<\/jats:p>","DOI":"10.1111\/ped.13180","type":"journal-article","created":{"date-parts":[[2017,1,19]],"date-time":"2017-01-19T18:48:31Z","timestamp":1484851711000},"page":"97-98","source":"Crossref","is-referenced-by-count":4,"title":["Transient symptomatic worsening by atropine in opsoclonus\u2013myoclonus syndrome"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1375-5344","authenticated-orcid":false,"given":"Hirotsugu","family":"Miyoshi","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Critical Care Hiroshima University Hospital Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryuji","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Hiroshima University Hospital Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayano","family":"Yamaga","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Hiroshima University Hospital Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiaki","family":"Haraki","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Hiroshima University Hospital Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshimichi","family":"Yasuda","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Hiroshima University Hospital Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Hamada","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Hiroshima University Hospital Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Kawamoto","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Hiroshima University Hospital Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,1,19]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"488","article-title":"Ataxia\u2010opsoclonus\u2010myoclonus syndrome","volume":"57","author":"Pinsard N","year":"1981","journal-title":"Sem. 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