{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T02:20:10Z","timestamp":1790562010927,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,1,31]],"date-time":"2017-01-31T00:00:00Z","timestamp":1485820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is controversial information on outcome of school age individuals who lose the diagnosis of autism and achieve \u201coptimal outcome\u201d (OO). The present study assessed the autism symptoms and other psychiatric disorders in a group of children with a past history of autism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The subjects consisted of 26 individuals who had lost the diagnosis of autism 2\u20138 years previously. Clinical assessment was done with both parents and children. <jats:italic>Diagnostic and Statistical Manual of Mental Disorders<\/jats:italic> (5th edn; DSM\u2010V) criteria were used for diagnosis of autism spectrum disorder (ASD). In addition, Childhood Autism Rating Scale and Social Communication Questionnaire (current version) were used. Psychiatric disorders were assessed using the Kiddie Schedule for Affective Disorders and Schizophrenia for School\u2010Age Children Present and Lifetime Version (K\u2010SADS\u2010PL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>None of the participants met the criteria for ASD. Ninety\u2010two percent had a lifetime diagnosis and 81% had a present psychiatric disorder based on the K\u2010SADS. Attention\u2010deficit hyperactivity disorder, specific phobia and obsessive\u2013compulsive disorder were the most common disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Improved status with regard to autism symptomatology is maintained over time, but these individuals are vulnerable to developing other psychiatric disorders. It is crucial to maintain psychiatric follow up of children who move off the autism spectrum.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.13202","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T13:58:07Z","timestamp":1479304687000},"page":"416-421","source":"Crossref","is-referenced-by-count":14,"title":["What happens to children who move off the autism spectrum? Clinical follow\u2010up study"],"prefix":"10.1111","volume":"59","author":[{"given":"Nahit Motavalli","family":"Mukaddes","sequence":"first","affiliation":[{"name":"Istanbul Institute of Child and Adolescent Psychiatry Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuba","family":"Mutluer","sequence":"additional","affiliation":[{"name":"Child and Adolescent Psychiatry Clinic Koc University Hospital Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basak","family":"Ayik","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Bakirkoy Research and Training Hospital for Psychiatric and Neurological Diseases Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayla","family":"Umut","sequence":"additional","affiliation":[{"name":"Istanbul Institute of Child and Adolescent Psychiatry Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,1,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-1601"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007870200003"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2010.05.004"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-005-5066-3"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12037"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-006-0340-6"},{"key":"e_1_2_8_9_1","first-page":"195","article-title":"Retrospective analysis of clinical records in 38 cases of recovery from autism","volume":"21","author":"Granpeesheh D","year":"2009","journal-title":"Ann. 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