{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T06:11:53Z","timestamp":1694758313116},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,4,24]],"date-time":"2017-04-24T00:00:00Z","timestamp":1492992000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A total of 16 cases of congenital fibrosarcoma have been reported from 1975 to March 2015. Five of the 16 had abnormal fusion between erythroblast transformation specific translocation variant 6 and neurotrophin recptor gene neurotrophic tyrosine kinase, receptor, type 3 (<jats:italic><jats:styled-content style=\"fixed-case\">ETV<\/jats:styled-content>6\u2013<jats:styled-content style=\"fixed-case\">NTRK<\/jats:styled-content>3<\/jats:italic>); in another five out of 16 this was absent, and six were not tested. All were managed by surgical resection but none involved metastasis. Herein we report the case of a newborn baby girl with congenital fibrosarcoma negative for <jats:italic><jats:styled-content style=\"fixed-case\">ETV<\/jats:styled-content>6\u2013<jats:styled-content style=\"fixed-case\">NTRK<\/jats:styled-content>3<\/jats:italic> gene fusion, who presented with ileal perforation and positive resection margin. She had rapid recurrence with lymph node metastasis treated with postoperative chemotherapy. There was no further recurrence at &gt;3\u00a0years of follow up.<\/jats:p>","DOI":"10.1111\/ped.13252","type":"journal-article","created":{"date-parts":[[2017,4,24]],"date-time":"2017-04-24T11:31:23Z","timestamp":1493033483000},"page":"733-736","source":"Crossref","is-referenced-by-count":0,"title":["Congenital intestinal fibrosarcoma with rapid recurrence requiring adjuvant chemotherapy"],"prefix":"10.1111","volume":"59","author":[{"given":"Wing Shan Queenie","family":"See","sequence":"first","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine Queen Mary Hospital University of Hong Kong Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel Ka Leung","family":"Cheuk","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine Queen Mary Hospital University of Hong Kong Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ka Fai","family":"To","sequence":"additional","affiliation":[{"name":"Department of Anatomical and Cellular Pathology Prince of Wales Hospital Chinese University of Hong Kong Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip Pun Ching","family":"Ip","sequence":"additional","affiliation":[{"name":"Department of Pathology Queen Mary Hospital University of Hong Kong Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan Kwok Shing","family":"Chiang","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine Queen Mary Hospital University of Hong Kong Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shau Yin","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine Queen Mary Hospital University of Hong Kong Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Godfrey Chi Fung","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine Queen Mary Hospital University of Hong Kong Hong Kong Hong 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