{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T20:11:08Z","timestamp":1791576668733,"version":"4.3.4"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,7,26]],"date-time":"2017-07-26T00:00:00Z","timestamp":1501027200000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this study was to examine the sensitivity and specificity of pyuria\u2010based diagnosis of urinary tract infection (<jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>) in urine collected by transurethral catheterization, and the reliability of diagnosis of pyuria in urine collected in a perineal bag. The gold standard for <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> diagnosis is significant colony counts of a single organism in urine obtained in a sterile manner.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We enrolled 301 patients who underwent medical examination at the present hospital for possible <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> between January 2005 and December 2009. We collected 438 urine samples by transurethral catheterization. We investigated the accuracy of pyuria\u2010based diagnosis of <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> using transurethral catheterization urine specimens, and the reliability of diagnosis of pyuria using bag\u2010collected urine specimens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The false\u2010negative rate of <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> diagnosis based on pyuria in transurethral catheterization urine sediments was 9.0%; there was no significant difference in the false\u2010negative rate of <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> diagnosis between boys and girls. Approximately 28% of pyuria\u2010positive bag\u2010collected urine specimens were pyuria negative on transurethral catheterization; this rate was significantly higher in girls than in boys (56.7% vs. 8.9%, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The absence of pyuria in transurethral catheterization urine sediments does not rule out <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>. Pyuria in bag\u2010collected urine specimens frequently consists of urine leukocytes from external genitalia as well as from the urinary tract.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.13292","type":"journal-article","created":{"date-parts":[[2017,4,8]],"date-time":"2017-04-08T06:49:49Z","timestamp":1491634189000},"page":"786-792","source":"Crossref","is-referenced-by-count":12,"title":["Pitfalls of diagnosing urinary tract infection in infants and young children"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2857-9950","authenticated-orcid":false,"given":"Yasuhito","family":"Yamasaki","sequence":"first","affiliation":[{"name":"Department of Pediatric Nephrology Aichi Children's Health and Medical Center Obu Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Uemura","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology Aichi Children's Health and Medical Center Obu Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuhito","family":"Nagai","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology Aichi Children's Health and Medical Center Obu Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9782-7415","authenticated-orcid":false,"given":"Satoshi","family":"Yamakawa","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology Aichi Children's Health and Medical Center Obu Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiko","family":"Hibi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology Aichi Children's Health and Medical Center Obu Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology Aichi Children's Health and Medical Center Obu Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaru","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology Aichi Children's Health and Medical Center Obu Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuaki","family":"Kasahara","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology Aichi Children's Health and Medical Center Obu Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhang","family":"Bo","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Fukuoka University School of Medicine Jonanku Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.103.4.e54"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-1330"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1179\/146532805X23326"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000273068"},{"key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1542\/peds.23.3.441","article-title":"Specimens of urine obtained from young girls by catheter versus voiding; 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