{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:55:24Z","timestamp":1758477324287,"version":"3.37.3"},"reference-count":13,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,8,30]],"date-time":"2017-08-30T00:00:00Z","timestamp":1504051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hydrops fetalis (<jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content>) has a low survival rate, particularly in the case of preterm birth. In addition, the severity index of <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content> has not been fully investigated yet. The aim of this study was to clarify the prognostic factors of <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content> with pleural effusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All live\u2010born <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content> patients with pleural effusion, except for chromosomal abnormality or complex congenital heart disease, born from 2009 to 2013 in Aichi Prefecture in Japan were included. Prenatal, perinatal, and postnatal information was obtained from the medical records and was retrospectively analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010one <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content> patients with pleural effusion were included, and 28 patients (68%) survived. On multivariate logistic stepwise analysis, gestational birth week (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>, 0.71; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.52\u20130.96, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.027) and standard deviation (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) score of the birthweight (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>, 1.74; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.01\u20132.99, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.045) were significant factors for postnatal death. All patients with both \u226532 gestational weeks and &lt;3.0 birthweight <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> score survived.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Combined with the gestational weeks data, birthweight <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> score may be useful to estimate the prognosis of <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content> with pleural effusion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.13357","type":"journal-article","created":{"date-parts":[[2017,7,3]],"date-time":"2017-07-03T19:12:38Z","timestamp":1499109158000},"page":"1053-1057","source":"Crossref","is-referenced-by-count":5,"title":["Prognostic factors of hydrops fetalis with pleural effusion"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7513-1767","authenticated-orcid":false,"given":"Atsushi","family":"Nakayama","sequence":"first","affiliation":[{"name":"Department of Pediatrics Japanese Red Cross Nagoya Daiichi Hospital Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Oshiro","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Japanese Red Cross Nagoya Daiichi Hospital Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasumasa","family":"Yamada","sequence":"additional","affiliation":[{"name":"Division of Reproductive and Perinatal Medical Center Aichi Medical University Hospital Nagakute Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuo","family":"Hattori","sequence":"additional","affiliation":[{"name":"Department of Neonatology Anjo Kosei Hospital Anjo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Wakano","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Neonatology Nagoya City University Graduate School of Medical Sciences Nagoya Japan"},{"name":"Department of Pediatrics Ichinomiya Municipal Hospital Ichinomiya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiji","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Okazaki City Hospital Okazaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minoru","family":"Kokubo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Aichi Prefectural Welfare Federation of Agricultural Cooperatives Kainan Hospital Yatomi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Takemoto","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Konan Kosei Hospital Konan Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Honda","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Komaki City Hospital Komaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuniko","family":"Ieda","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Tosei General Hospital Seto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hikaru","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Neonatology Toyota Memorial Hospital Toyota Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Kouwaki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Toyohashi Municipal Hospital Toyohashi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoko","family":"Yokoi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Nagoya City West Medical Center Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Shinohara","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Handa City Hospital Handa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takenori","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Neonatology Nagoya City University Graduate School of Medical Sciences Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masafumi","family":"Miyata","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Fujita Health University School of Medicine Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taihei","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Japanese Red Cross Nagoya Daini Hospital Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Hayakawa","sequence":"additional","affiliation":[{"name":"Division of Neonatology Center for Maternal\u2013Neonatal Care Nagoya University Hospital Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,8,30]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32655"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2001.080008726.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/jmf.10.3.175.181-9"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2677"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2006.tb02342.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(86)80026-6"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.12.018"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-958158"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2012.244"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.3840"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.05.016"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7507"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1768"}],"container-title":["Pediatrics International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fped.13357","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.13357","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T16:38:11Z","timestamp":1694709491000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ped.13357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,30]]},"references-count":13,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1111\/ped.13357"],"URL":"https:\/\/doi.org\/10.1111\/ped.13357","archive":["Portico"],"relation":{},"ISSN":["1328-8067","1442-200X"],"issn-type":[{"type":"print","value":"1328-8067"},{"type":"electronic","value":"1442-200X"}],"subject":[],"published":{"date-parts":[[2017,8,30]]}}}