{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T14:49:33Z","timestamp":1785768573232,"version":"3.56.0"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,6,19]],"date-time":"2018-06-19T00:00:00Z","timestamp":1529366400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2018,6]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Admission to the neonatal intensive care unit (NICU<\/jats:styled-content>) due to respiratory distress is determined according to subjective clinician judgement. We investigated prenatal factors predictive of NICU<\/jats:styled-content> admission in neonates with respiratory distress.<\/jats:p><\/jats:sec>Methods<\/jats:title>This case\u2013control study was conducted at Nara Prefecture General Medical Center, Nara, Japan, from February 2013 to April 2017 and included neonates with birthweight \u22652,000\u00a0g, \u226536\u00a0weeks of gestational age, who required oxygen due to respiratory distress at birth. The cases consisted of neonates admitted to the NICU<\/jats:styled-content>, and the control group consisted of neonates who did not require NICU<\/jats:styled-content> admission. Perinatal factors between the groups were compared, and multivariate logistic regression analysis carried out to evaluate predictive factors.<\/jats:p><\/jats:sec>Results<\/jats:title>The NICU<\/jats:styled-content> group consisted of 94 neonates, and the control group, 417 neonates during the period reviewed. On multivariate analysis, maternal anemia (OR<\/jats:styled-content>, 2.97; 95%CI<\/jats:styled-content>: 1.42\u20136.21), infertility treatment (OR<\/jats:styled-content>, 2.79; 95%CI<\/jats:styled-content>: 1.36\u20135.71), threatened preterm labor (OR<\/jats:styled-content>, 2.16; 95%CI<\/jats:styled-content>: 1.10\u20134.23), premature rupture of membranes (OR<\/jats:styled-content>, 5.30, 95%CI<\/jats:styled-content>: 2.52\u201311.17), fibroids (OR<\/jats:styled-content>, 6.06; 95%CI<\/jats:styled-content>: 1.57\u201323.41), history of uterine surgery (OR<\/jats:styled-content>, 3.53, 95%CI<\/jats:styled-content>: 1.13\u201311.06), abruptio placentae (OR<\/jats:styled-content>, 10.21; 95%CI<\/jats:styled-content>: 1.83\u201357.17), intrauterine growth restriction (OR<\/jats:styled-content>, 6.69; 95%CI<\/jats:styled-content>: 1.96\u201322.85), and having twins (OR<\/jats:styled-content>, 0.23; 95%CI<\/jats:styled-content>: 0.09\u20130.58) were significant prenatal predictors of NICU<\/jats:styled-content> admission.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Factors that potentially predict NICU<\/jats:styled-content> admission were identified. Clinicians may wish to consider these factors when treating neonates with respiratory distress.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.13574","type":"journal-article","created":{"date-parts":[[2018,4,14]],"date-time":"2018-04-14T07:25:17Z","timestamp":1523690717000},"page":"560-564","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Prenatal predictors of neonatal intensive care unit admission due to respiratory distress"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0623-066X","authenticated-orcid":false,"given":"Taito","family":"Kitano","sequence":"first","affiliation":[{"name":"Department of Neonatal Intensive Care Unit Nara Prefecture General Medical Center Nara Japan"},{"name":"Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumiko","family":"Takagi","sequence":"additional","affiliation":[{"name":"Department of Neonatal Intensive Care Unit Nara Prefecture General Medical Center Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikuyo","family":"Arai","sequence":"additional","affiliation":[{"name":"Department of Neonatal Intensive Care Unit Nara Prefecture General Medical Center Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Yasuhara","sequence":"additional","affiliation":[{"name":"Department of Neonatal Intensive Care Unit Nara Prefecture General Medical Center Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reiko","family":"Ebisu","sequence":"additional","affiliation":[{"name":"Department of Neonatal Intensive Care Unit Nara Prefecture General Medical Center Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Ohgitani","sequence":"additional","affiliation":[{"name":"Department of Neonatal Intensive Care Unit Nara Prefecture General Medical Center Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8430-8605","authenticated-orcid":false,"given":"Hideki","family":"Minowa","sequence":"additional","affiliation":[{"name":"Department of Neonatal Intensive Care Unit Nara Prefecture General Medical Center Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,6,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2007.00440.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.7.2012126"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211242"},{"key":"e_1_2_7_5_1","first-page":"170","article-title":"Admission to neonatal intensive care with respiratory morbidity following \u2018term\u2019 elective caesarean section","volume":"98","author":"Alderdice F","year":"2005","journal-title":"Ir. 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