{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T13:25:44Z","timestamp":1778678744578,"version":"3.51.4"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T00:00:00Z","timestamp":1555459200000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Bronchopulmonary dysplasia (<jats:styled-content style=\"fixed-case\">BPD<\/jats:styled-content>) is the most frequent chronic lung disease in infancy and is associated with neonatal comorbidity and impairment in pulmonary and neurodevelopmental (<jats:styled-content style=\"fixed-case\">ND<\/jats:styled-content>) long\u2010term outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective, single\u2010center, cohort study to compare a cohort of very preterm infants (gestational age [<jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content>], 24<jats:sup>+0<\/jats:sup>\u201328<jats:sup>+6<\/jats:sup> weeks) with <jats:styled-content style=\"fixed-case\">BPD<\/jats:styled-content> (<jats:italic>n<\/jats:italic> = 44), with a cohort of <jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content>\u2010matched preterm infants without <jats:styled-content style=\"fixed-case\">BPD<\/jats:styled-content> (<jats:italic>n<\/jats:italic> = 44) with regard to neonatal morbidity, incidence of lower respiratory tract infection (<jats:styled-content style=\"fixed-case\">LRTI<\/jats:styled-content>), <jats:styled-content style=\"fixed-case\">ND<\/jats:styled-content> outcome and growth to 2 years' corrected age (<jats:styled-content style=\"fixed-case\">CA<\/jats:styled-content>) and preschool age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Bronchopulmonary dysplasia (incidence, 11.3%) was associated with a higher rate of neonatal pneumonia (26% vs 7%, <jats:italic>P<\/jats:italic> = 0.001), longer total duration of mechanical ventilation (mean days, 21 vs 13, <jats:italic>P<\/jats:italic> &lt; 0.001), and a higher rate of pulmonary hypertension (20.5% vs 0%, <jats:italic>P<\/jats:italic> = 0.002) and of severe retinopathy of prematurity (13.6% vs 0%, <jats:italic>P<\/jats:italic> = 0.026). Incidence of <jats:styled-content style=\"fixed-case\">LRTI<\/jats:styled-content> was significantly higher in the <jats:styled-content style=\"fixed-case\">BPD<\/jats:styled-content> infants (50% vs 26%, <jats:italic>P<\/jats:italic> = 0.025). <jats:styled-content style=\"fixed-case\">ND<\/jats:styled-content> outcome did not differ between the two groups. Growth at neonatal intensive care unit discharge was similar. In the <jats:styled-content style=\"fixed-case\">BPD<\/jats:styled-content> cohort, rate of weight &lt; 10th percentile was higher at 2 years' <jats:styled-content style=\"fixed-case\">CA<\/jats:styled-content> (52% vs 30%, <jats:italic>P<\/jats:italic> = 0.041) and rate of head circumference &lt; 10th percentile was higher at preschool age (59% vs 27%, <jats:italic>P<\/jats:italic> = 0.028).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Neonatal respiratory morbidity was significantly higher in the <jats:styled-content style=\"fixed-case\">BPD<\/jats:styled-content> cohort, but long\u2010term <jats:styled-content style=\"fixed-case\">ND<\/jats:styled-content> outcome did not differ. Infants with <jats:styled-content style=\"fixed-case\">BPD<\/jats:styled-content> had poorer growth.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.13815","type":"journal-article","created":{"date-parts":[[2019,2,22]],"date-time":"2019-02-22T09:08:50Z","timestamp":1550826530000},"page":"381-387","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Bronchopulmonary dysplasia in very preterm infants: Outcome up to preschool age, in a single center of Austria"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9478-2693","authenticated-orcid":false,"given":"Friedrich","family":"Reiterer","sequence":"first","affiliation":[{"name":"Division of Neonatology Department of Pediatrics and Adolescence Medicine Medical University of Graz Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Scheuchenegger","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics and Adolescence Medicine Medical University of Graz Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Resch","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics and Adolescence Medicine Medical University of Graz Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ute","family":"Maurer\u2010Fellbaum","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics and Adolescence Medicine Medical University of Graz Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Avian","sequence":"additional","affiliation":[{"name":"Institute of Medical Informatics, Statistics and Documentation Medical University of Graz Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berndt","family":"Urlesberger","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics and Adolescence Medicine Medical University of Graz Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196702162760701"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.7.2011060"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.06.064"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.82.4.527"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e3283423e6b"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.10244"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7210963"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.5772\/54310"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80282-0"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(05)80189-5"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)34975-6"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-006-1709-5"},{"key":"e_1_2_7_14_1","first-page":"1130","article-title":"An international classification of retinopathy of prematurity","volume":"103","author":"Committee for the Classification of Retinopathy of Prematurity","year":"1982","journal-title":"Arch. 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