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Although most cases of infantile <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content> are benign tumors by nature, some develop into extremely large lesions, leading to massive bleeding, high\u2010output heart failure, disseminated intravascular coagulation, and even fatal outcomes during the neonatal period. In addition, some patients may present with tumor recurrence, malignant transformation, long\u2010term sequelae (including bladder and bowel dysfunction) and lower leg palsy during the long\u2010term follow up. <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content>, however, is very rare, and there are few opportunities to encounter this disease, therefore general physicians without expert credentials currently lack information relevant to clinical practice. For this reason, the research project committee has compiled guidelines concerning <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The purpose of these guidelines was to share information concerning the treatment and follow up of infantile <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content>. The guidelines were developed using the methodologies in the Medical Information Network Distribution System. A comprehensive search of the English\u2010 and Japanese\u2010language articles in PubMed and Ichu\u2010Shi Web identified only case reports or case series, and the recommendations were developed through a process of informal consensus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The clinical questions addressed the risk factors, the efficacy of cesarean section, the initial devascularization of tumor feeding vessels, interventional radiology, recommended clinical studies for follow up and possible long\u2010term complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These are the first guidelines for <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content> to be established in Japan, and they may have huge clinical value and significance in terms of developing therapeutic strategies and follow up, potentially contributing to the improvement of the prognosis and quality of life of <jats:styled-content 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