{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T22:32:48Z","timestamp":1771021968905,"version":"3.50.1"},"reference-count":49,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T00:00:00Z","timestamp":1562630400000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Platelet mass index (<jats:styled-content style=\"fixed-case\">PMI<\/jats:styled-content>) is associated with platelet functionality. The aim of this study was to evaluate the role of <jats:styled-content style=\"fixed-case\">PMI<\/jats:styled-content> in predicting the severity of transient tachypnea of the newborn (<jats:styled-content style=\"fixed-case\">TTN<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Infants with gestational age \u226537\u00a0weeks and birthweight \u22652,000\u00a0g who were given nasal intermittent mandatory ventilation for <jats:styled-content style=\"fixed-case\">TTN<\/jats:styled-content> \u22646\u00a0h after birth were retrospectively enrolled in this study. <jats:styled-content style=\"fixed-case\">PMI<\/jats:styled-content> was calculated using the following formula: <jats:styled-content style=\"fixed-case\">PMI<\/jats:styled-content> = platelet count \u00d7 mean platelet volume\/10<jats:sup>3<\/jats:sup> (<jats:styled-content style=\"fixed-case\">fL<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">nL<\/jats:styled-content>). The study infants (<jats:italic>n<\/jats:italic> = 101) were divided into two groups according to the duration of tachypnea: \u226448\u00a0h (<jats:italic>n<\/jats:italic> = 45) and &gt;48\u00a0h (<jats:italic>n<\/jats:italic> = 56).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">PMI<\/jats:styled-content> and platelet count were significantly lower in the group with tachypnea duration &gt;48\u00a0h than in the tachypnea duration \u226448\u00a0h group (<jats:italic>P<\/jats:italic> &lt; 0.001 and <jats:italic>P<\/jats:italic> = 0.04, respectively). A negative significant correlation was noted between <jats:styled-content style=\"fixed-case\">PMI<\/jats:styled-content> and the duration of tachypnea (<jats:italic>r<\/jats:italic> = \u22120.43, <jats:italic>P<\/jats:italic> &lt; 0.001). A <jats:styled-content style=\"fixed-case\">PMI<\/jats:styled-content> cut\u2010off of 1,562 <jats:styled-content style=\"fixed-case\">fL<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">nL<\/jats:styled-content> can predict prolonged tachypnea (&gt;48\u00a0h) with a sensitivity of 62.5%, specificity of 68.9%, positive predictive value of 71.4%, and negative predictive value of 59.6% (area under the curve, 0.682 \u00b1 0.053; <jats:italic>P<\/jats:italic> = 0.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Lower <jats:styled-content style=\"fixed-case\">PMI<\/jats:styled-content> and lower platelet count are associated with longer duration of tachypnea in patients with <jats:styled-content style=\"fixed-case\">TTN<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.13899","type":"journal-article","created":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T01:59:46Z","timestamp":1559095186000},"page":"697-705","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Platelet mass index and prediction of severity of transient tachypnea of the newborn"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6124-9796","authenticated-orcid":false,"given":"Ozkan","family":"Ilhan","sequence":"first","affiliation":[{"name":"Department of Neonatology Harran University School of Medicine Sanliurfa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meltem","family":"Bor","sequence":"additional","affiliation":[{"name":"Department of Neonatology Harran University School of Medicine Sanliurfa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1966.02090070078010"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000209300"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2012.02.002"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2008.03.004"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physiol-030212-183752"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000243210"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(87)80517-6"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.4038\/sljch.v44i4.8045"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12105"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001721-199603000-00011"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2009.02820.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/crj.12723"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1824-7288-39-16"},{"key":"e_1_2_7_15_1","first-page":"2983","article-title":"The association between mean platelet volume and infants with meconium\u2010stained amniotic fluid","volume":"20","author":"Tekin M","year":"2016","journal-title":"Eur. 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