{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:32:33Z","timestamp":1791563553574,"version":"4.3.4"},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,11,13]],"date-time":"2019-11-13T00:00:00Z","timestamp":1573603200000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this study was to investigate the risk factors for acquisition of extended spectrum \u03b2\u2010lactamase (ESBL)\u2010producing bacteria in community\u2010acquired urinary tract infection (UTI) and to evaluate their antimicrobial resistance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The medical records of hospitalized children were retrospectively evaluated. Children with ESBL\u2010producing bacteria UTI were matched with controls with non\u2010ESBL\u2010producing bacteria UTI of the same age and gender.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 243 patients with community\u2010acquired UTI in a 5\u00a0year period were evaluated, of whom 46% had UTI caused by ESBL bacteria. Seventy\u2010seven cases were matched with 77 controls. There were no significant differences in the clinical presentation between the two groups apart from a longer hospital stay in the ESBL group (9.1 \u00b1 5.5\u00a0days vs 8.0 \u00b1 4.4\u00a0days, <jats:italic>P\u00a0=\u00a0<\/jats:italic>0.013). Significant potential risk factors for ESBL\u2010UTI were previous use of antibiotics in the last 3\u00a0months, previous hospitalization in the last 3\u00a0months, history of recurrent UTI, and presence of renal anomalies. On logistic regression analysis, history of previous hospitalization in the last 3\u00a0months (OR, 3.83; 95%CI: 1.49\u20139.84) was identified as an independent significant risk factor for ESBL\u2010UTI. There was a significantly higher resistance to amoxicillin\u2010clavulanate, amikacin, gentamycin and quinolones in the ESBL group compared with the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Recognizing the risk factors for ESBL\u2010UTI helps to identify the high\u2010risk cases and enables proper management.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.13911","type":"journal-article","created":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T15:36:05Z","timestamp":1560785765000},"page":"1127-1132","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Urinary tract infection caused by extended\u2010spectrum \u03b2\u2010lactamase\u2010producing bacteria: Risk factors and antibiotic resistance"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5917-0379","authenticated-orcid":false,"given":"Jumana H","family":"Albaramki","sequence":"first","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Jordan Amman Jordan"},{"name":"Department of Pediatrics Jordan University Hospital University of Jordan Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariq","family":"Abdelghani","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Jordan Amman Jordan"},{"name":"Department of Pediatrics Jordan University Hospital University of Jordan Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alaa","family":"Dalaeen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Jordan Amman Jordan"},{"name":"Department of Pediatrics Jordan University Hospital University of Jordan Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fareed","family":"Khdair Ahmad","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Jordan Amman Jordan"},{"name":"Department of Pediatrics Jordan University Hospital University of Jordan Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abeer","family":"Alassaf","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Jordan Amman Jordan"},{"name":"Department of Pediatrics Jordan University Hospital University of Jordan Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasha","family":"Odeh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Jordan Amman Jordan"},{"name":"Department of Pediatrics Jordan University Hospital University of Jordan Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamal","family":"Akl","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of Jordan Amman Jordan"},{"name":"Department of Pediatrics Jordan University Hospital University of Jordan Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2016.1181"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70041-0"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.14.4.933-951.2001"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2016.04.021"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2013.05.006"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2016.07.014"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-009-1431-3"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2013.06.078"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2012.03709.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-014-2810-y"},{"key":"e_1_2_8_12_1","first-page":"248","article-title":"Clinical implications and risk factors of extended\u2010spectrum beta\u2010lactamase\u2010producing Klebsiella pneumoniae infection in children: A case\u2010control retrospective study in a medical center in southern Taiwan","volume":"40","author":"Kuo KC","year":"2007","journal-title":"J. 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