{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:14:28Z","timestamp":1792095268438,"version":"4.4.0"},"reference-count":24,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T00:00:00Z","timestamp":1562025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Congenital pulmonary malformations (<jats:styled-content style=\"fixed-case\">CPM<\/jats:styled-content>) are a group of rare abnormal lung development lesions that can have various presentations. The aim of this study was to define the differences in the clinical presentations of <jats:styled-content style=\"fixed-case\">CPM<\/jats:styled-content> in neonates, infants, and children, and to review the outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study was conducted at a tertiary care hospital in southern Thailand between 1992 and 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010four patients were diagnosed with CPM, and the median age at onset was 1.7\u00a0months (IQR, 0.03\u201310\u00a0months). There were 33 cases (61.1%) of congenital pulmonary airway malformations, two (3.7%) of bronchogenic cyst, eight of (14.8%) congenital lobar emphysema, seven of\u00a0(13.0%) pulmonary sequestrations, and four\u00a0of (7.4%) congenital lung cysts. Twenty patients under 1 month old and 16 patients who were 1\u201312 months old had symptoms of respiratory distress. In contrast, 13 patients &gt;1 year old had symptoms of pulmonary infection. There were significant differences in the numbers of patients who had cyanosis (<jats:italic>P<\/jats:italic> = 0.006), cough (<jats:italic>P<\/jats:italic> &lt; 0.001), and fever (<jats:italic>P<\/jats:italic> &lt; 0.001) between the three age groups. Thirty\u2010eight patients (70%) required surgical treatment involving lobectomy (78.9%). Median follow\u2010up duration was 28.1\u00a0months (IQR, 3.7\u20139.4\u00a0months). Nine of 10 patients had abnormal lung function tests, and 80.6% of patients had no subsequent limitations in physical activities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Respiratory distress is the important clinical feature in neonates and infants, whereas the signs of pulmonary infection usually occur in children &gt;1 year old. Good outcomes usually occur after surgery but need long\u2010term follow up including lung function assessment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.13934","type":"journal-article","created":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T08:34:46Z","timestamp":1562056486000},"page":"812-816","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Clinical presentation and outcome in congenital pulmonary malformation: 25\u00a0year retrospective study in Thailand"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6332-3216","authenticated-orcid":false,"given":"Gunlawadee","family":"Maneenil","sequence":"first","affiliation":[{"name":"Division of Neonatology Department of Pediatrics Faculty of Medicine Prince of Songkla University Hat Yai, Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanokpan","family":"Ruangnapa","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine Department of Pediatrics Faculty of Medicine Prince of Songkla University Hat Yai, Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anucha","family":"Thatrimontrichai","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics Faculty of Medicine Prince of Songkla University Hat Yai, Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waricha","family":"Janjindamai","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics Faculty of Medicine Prince of Songkla University Hat Yai, Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supaporn","family":"Dissaneevate","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics Faculty of Medicine Prince of Songkla University Hat Yai, Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanaporn","family":"Anantaseree","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine Department of Pediatrics Faculty of Medicine Prince of Songkla University Hat Yai, Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somchai","family":"Suntornlohanakul","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine Department of Pediatrics Faculty of Medicine Prince of Songkla University Hat Yai, Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2007.10.002"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20300"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000440894"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2015.01.013"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)38443-7"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00035005"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(98)00262-0"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-2988"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23472"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2004.10.015"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.1.98"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2000.6088"},{"key":"e_1_2_8_14_1","first-page":"Sc01","article-title":"Congenital cystic adenomatoid malformation: A tertiary care hospital experience","volume":"10","author":"Mehta AA","year":"2016","journal-title":"J. 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