{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T22:16:56Z","timestamp":1757456216490,"version":"3.40.5"},"reference-count":21,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T00:00:00Z","timestamp":1576454400000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Women with congenital heart disease (<jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>) commonly experience complications related to <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content> during pregnancy. The clinical features of neonates born to mothers with <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>, however, have not been fully investigated. The frequency of small for gestational age (<jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>) is high in infants born to mothers with <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>, but the risk factors have not been examined sufficiently. Therefore, we analyzed the maternal features associated with <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>We enrolled pregnant women with repaired <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content> and infants born to them at Tokyo Women's Medical University Hospital between April 2007 and March 2015. Eleven <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> (11%) and 91 non\u2010<jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> infants (89%) were included. On multivariate logistic regression, <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> infants were significantly more likely to be associated with a high maternal brain\u2010type natriuretic peptide (<jats:styled-content style=\"fixed-case\">BNP<\/jats:styled-content>) level (OR, 6.7; 95%CI: 1.3\u201334.5; <jats:italic>P<\/jats:italic> = 0.02) and maternal single ventricle disease (OR, 8.4; 95%CI:1.4\u201351.8; <jats:italic>P<\/jats:italic> = 0.02) than were non\u2010<jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The incidence of <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> infants born to mothers with <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content> was not high in this study. High <jats:styled-content style=\"fixed-case\">BNP<\/jats:styled-content> and maternal single ventricle disease, however, are independent predictors of <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> in infants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.13997","type":"journal-article","created":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T22:00:39Z","timestamp":1567029639000},"page":"1221-1226","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Brain\u2010type natriuretic peptide level in pregnant women with congenital heart disease predicts <scp>SGA<\/scp> offspring"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5050-1247","authenticated-orcid":false,"given":"Shuji","family":"Ishida","sequence":"first","affiliation":[{"name":"Department of Neonatal Medicine, Maternal and Perinatal Center Tokyo Women's Medical University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0339-8571","authenticated-orcid":false,"given":"Atsushi","family":"Uchiyama","sequence":"additional","affiliation":[{"name":"Department of Neonatal Medicine, Maternal and Perinatal Center Tokyo Women's Medical University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Imai","sequence":"additional","affiliation":[{"name":"Department of Neonatal Medicine, Maternal and Perinatal Center Tokyo Women's Medical University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Kusuda","sequence":"additional","affiliation":[{"name":"Department of Neonatal Medicine, Maternal and Perinatal Center Tokyo Women's Medical University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,12,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/heart.85.5.493"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.03.027"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc3001.093437"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-013-0401-3"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2011.03.005"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2014.12.001"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0022-3476(03)00181-1"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-4-9"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.12.097"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000210"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(67)80066-0"},{"key":"e_1_2_8_13_1","first-page":"1771","article-title":"Introduction of new gestational age\u2010specific standards for birth size","volume":"114","author":"Itabashi K","year":"2010","journal-title":"J. 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