{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T12:33:24Z","timestamp":1793363604736,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T00:00:00Z","timestamp":1636416000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T00:00:00Z","timestamp":1636416000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Scorpionism is endemic and represents a real public health problem in Morocco. The most dangerous arthropod in the central area is\n                      <jats:italic>Androctonus mauretanicus<\/jats:italic>\n                      (Am) scorpion. Its venom can be lethal, especially for children. This study aimed to determine a clinico\u2010epidemiological profile of severe scorpion envenomation among children and identify risk factors for mortality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study included 606 children admitted for severe scorpion envenomation (SSE) from January 2010 to July 2015 in the Pediatric Intensive Care Unit (PICU) of Mohammed VI Teaching Hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean age of envenomed children was 6.3 \u00b1 4.2\u2009years. Seventy\u2010four percent of them came from rural settings. Envenomation occurred mostly during the summer months and 78.4% of stings were nocturnal. The time between the sting and evaluation was greater than 2\u2009h in 83% of cases. Bivariate analysis indicated that from 1 to 24\u2009months of age (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.001), hyperthermia (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.022), episodes of diarrhea (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001), tachycardia (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001), abdominal distention (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001), skin marbling (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001), signs of respiratory distress (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001), irritability (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001), generalized seizures (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.053), and Glasgow Coma Score (GCS) of 3 to 9 (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001) were significantly correlated with mortality. On multivariate analysis, diarrhea (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.007), skin marbling (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.006), and respiratory distress (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.002), and GCS 3\u20109 (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.007) were found to be independent risk factors for mortality in our patient population.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Children are at high risk of developing serious complications, even death, from severe scorpion envenomation. Here we identified multiple factors that appear to increase the mortality risk in children after scorpion envenomation, including previously described central nervous system alterations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ped.14687","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T02:56:16Z","timestamp":1615172176000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Clinical features and prognosis of severe scorpion envenomation in children"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9938-9551","authenticated-orcid":false,"given":"Houssam","family":"Rebahi","sequence":"first","affiliation":[{"name":"Department of Anesthesia &amp; Intensive Care Medicine Faculty of Medicine &amp; Pharmacy of Marrakech Cadi Ayyad University Marrakech Morocco"},{"name":"Laboratory of Childhood, Health &amp; Development Faculty of Medicine &amp; Pharmacy of Marrakech Cadi Ayyad University Marrakech Morocco"},{"name":"Laboratory of Pharmacology, Neurobiology and Behavior (URAC\u201037) Faculty of Sciences Semlalia Cadi Ayyad University Marrakech Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saadia","family":"Ba\u2010M\u2019hamed","sequence":"additional","affiliation":[{"name":"Laboratory of Pharmacology, Neurobiology and Behavior (URAC\u201037) Faculty of Sciences Semlalia Cadi Ayyad University Marrakech Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan Elizabeth","family":"Still","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center Dallas TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youssef","family":"Mouaffak","sequence":"additional","affiliation":[{"name":"Department of Anesthesia &amp; Intensive Care Medicine Faculty of Medicine &amp; Pharmacy of Marrakech Cadi Ayyad University Marrakech Morocco"},{"name":"Laboratory of Childhood, Health &amp; Development Faculty of Medicine &amp; Pharmacy of Marrakech Cadi Ayyad University Marrakech Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Younous","sequence":"additional","affiliation":[{"name":"Department of Anesthesia &amp; Intensive Care Medicine Faculty of Medicine &amp; Pharmacy of Marrakech Cadi Ayyad University Marrakech Morocco"},{"name":"Laboratory of Childhood, Health &amp; Development Faculty of Medicine &amp; Pharmacy of Marrakech Cadi Ayyad University Marrakech Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Bennis","sequence":"additional","affiliation":[{"name":"Laboratory of Pharmacology, Neurobiology and Behavior (URAC\u201037) Faculty of Sciences Semlalia Cadi Ayyad University Marrakech Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2008.05.021"},{"key":"e_1_2_11_3_1","first-page":"341","article-title":"Epidemiological aspects of scorpion stings in Morocco","volume":"50","author":"Soulaymani\u2010Bencheikh R","year":"2002","journal-title":"Rev. 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