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The brain regional oxygen saturation index (rSO\n                      <jats:sub>2<\/jats:sub>\n                      ) can be easily obtained at the bedside with near\u2010infrared spectroscopy and has been widely used in the management of children with CHD in recent years.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      To determine if the rSO\n                      <jats:sub>2<\/jats:sub>\n                      before or after CHD surgery is a good predictor of cerebral oxygen metabolism, we investigated the impact of different clinical variables on the correlation between rSO\n                      <jats:sub>2<\/jats:sub>\n                      and reference values under steady ratios of hemoglobin oxygen saturation in the internal jugular vein (SjvO\n                      <jats:sub>2<\/jats:sub>\n                      ) or femoral artery (SaO\n                      <jats:sub>2<\/jats:sub>\n                      ) (0.75:0.25, 0.66:0.34, and 0.50:0.50) in 186 children with CHD undergoing cardiac catheterization.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In three patient groups\u2014double ventricles before surgery, double ventricles after surgery, and single ventricle before surgery\u2014there were significant relationships between rSO\n                      <jats:sub>2<\/jats:sub>\n                      and the reference values of SO\n                      <jats:sub>2<\/jats:sub>\n                      under all three steady ratios of SjvO\n                      <jats:sub>2<\/jats:sub>\n                      and SaO\n                      <jats:sub>2<\/jats:sub>\n                      . No relationship with the reference values was found for the single ventricle after surgery group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Regional oxygen saturation index is useful for assessing cerebral oxygenation in children with CHD, but knowledge of the underlying cardiac pathology in CHD, especially in the case of a single ventricle after surgery, is important for the correct interpretation of rSO\n                      <jats:sub>2<\/jats:sub>\n                      measurements obtained using near\u2010infrared spectroscopy.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ped.14726","type":"journal-article","created":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T16:23:52Z","timestamp":1617812632000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Cerebral hemoglobin oxygenation in children with congenital heart disease"],"prefix":"10.1111","volume":"64","author":[{"given":"Kazuya","family":"Terada","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology Shikoku Medical Center for Children and Adults Kagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Maternal Perinatal Center Faculty of Medicine Kagawa University Kagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Nakao","sequence":"additional","affiliation":[{"name":"Maternal Perinatal Center Faculty of Medicine Kagawa University 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