{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:45:32Z","timestamp":1775695532136,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,1,29]],"date-time":"2022-01-29T00:00:00Z","timestamp":1643414400000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patent ductus arteriosus (PDA), which disrupts the hemodynamics early after birth, causes intraventricular hemorrhage and neonatal necrotizing. Unlike medical treatment for hemodynamically significant PDA, there are institutional disparities in the criteria for surgical treatment<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We aimed to clarify the postoperative indications of surgery for hemodynamically significant PDA and the postoperative complications associated with surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010six extremely\u2010low\u2010birthweight infants (median gestational age 25.2\u2009weeks, median birthweight 699\u2009g) required video\u2010assisted thoracoscopic surgery for PDA (VATS\u2010PDA). The treatment indication of VATS\u2010PDA was resistance to medical treatment in 17 cases, relapsed PDA in 15 cases, and no additional administration of indomethacin because of severe side effects in four cases. Complications with VATS\u2010PDA occurred in eight of 36 cases. There were three cases of pneumothorax, two of thoracotomy transition, two of pulmonary hemorrhage, and four of post\u2010ligation cardiac syndrome (PLCS). VATS\u2010PDA\u2010related death occurred in two cases due to PLCS. The frequency of four or more administrations of indomethacin, with or without postoperative complications, was 88% vs. 39%, respectively (<jats:italic>P<\/jats:italic> = 0.04).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>All postoperative deaths were caused by PLCS, which had the highest risk of poor prognosis. VATS\u2010PDA should be considered for unclosed PDA after one course of indomethacin administration.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.14759","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T19:00:55Z","timestamp":1619809255000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Evaluation of postoperative complications for patent ductus arteriosus in extremely\u2010low\u2010birthweight infants"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5050-1247","authenticated-orcid":false,"given":"Shuji","family":"Ishida","sequence":"first","affiliation":[{"name":"Department of Pediatrics Kitasato University Hospital Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayano","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kitasato University Hospital Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari","family":"Ooka","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kitasato University Hospital Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manabu","family":"Kenmochi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kitasato University Hospital Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidehiko","family":"Nakanishi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kitasato University Hospital Kanagawa Japan"},{"name":"Division of Neonatal Intensive Care Medicine Research and Development Center for New Medical Frontiers Kitasato University School of Medicine Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,1,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-015-0059-6"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-0925"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27808"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-010-9863-x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2006.03.002"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.5603\/KP.2018.0009"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.104.2.227"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivv185"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)33812-7"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(03)00682-9"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2003.12.023"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-018-0056-4"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-010-0137-7"},{"key":"e_1_2_9_15_1","unstructured":"Japanese Preterm PDA Guideline Group (J\u2010PreP Guideline Group).Clinical practice guideline for the management of patent ductus arteriosus in preterm or low birth weight infants 2010. Osaka: Japan Society for Premature and Newborn Medicine;. 2010.508. 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