{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T21:59:58Z","timestamp":1790200798210,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T00:00:00Z","timestamp":1649376000000},"content-version":"vor","delay-in-days":97,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pediatric liver transplant (LT) candidates often miss complete varicella\u2010zoster virus (VZV) vaccination before LT. We aimed to evaluate the immunogenicity of two doses of VZV vaccines in pediatric LT candidates younger than 2\u2009years and persistence of its immunogenicity after LT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients aged 9\u201324\u2009months were enrolled before LT. The first dose of VZV vaccine was given at 9\u2009months, and the second dose was given at between 1 to 3\u2009months later, and at least 4\u2009weeks before LT. Varicella\u2010zoster IgG (VZG) was used to detect immunoglobulin G antibodies to VZV and was reported as a test value (TV). A test value \u2265 0.9 was considered as seropositive. TV was measured at enrollment, 1\u2009month after the first and the second dose of VZV vaccine, before LT, and 3 and 6\u2009months after LT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fourteen children were enrolled in this prospective cohort study. The median age at the first and the second dose of VZV vaccine was 11.5 months (IQR 9\u201312) and 13 months (IQR 12\u201333), respectively. The seroconversion rate was 66.7% (8\/12) and 70% (7\/10) after the first and second VZV vaccine doses, respectively. Seven of nine patients who underwent LT had two doses of VZV vaccine. Six patients were seropositive before LT, which persisted at 3 to 6\u2009months after LT. Of two patients who received only one dose, TV was not detected after LT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The two doses of VZV vaccine appeared to be more immunogenic than one dose in pediatric LT candidates aged less than 2\u2009years.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ped.14934","type":"journal-article","created":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T15:56:53Z","timestamp":1627574213000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Immunogenicity of varicella zoster vaccine in pediatric liver transplantation"],"prefix":"10.1111","volume":"64","author":[{"given":"Thanwarat","family":"Atjayutpokin","sequence":"first","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suporn","family":"Treepongkaruna","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand"},{"name":"Ramathibodi Excellent Center for Organ Transplantation Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nopporn","family":"Apiwattanakul","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chonnamet","family":"Techasaensiri","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chatmanee","family":"Lertudomphonwanit","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand"},{"name":"Ramathibodi Excellent Center for Organ Transplantation Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songpon","family":"Getsuwan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand"},{"name":"Ramathibodi Excellent Center for Organ Transplantation Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6027-0534","authenticated-orcid":false,"given":"Sophida","family":"Boonsathorn","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2009.01204.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.6.704"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365540902968027"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2003.09.006"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69561-5"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.85.2.83"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200103293441302"},{"issue":"11","key":"e_1_2_8_9_1","first-page":"1","article-title":"Prevention of varicella: recommendations of the Advisory Committee on Immunization Practices (ACIP)","volume":"56","author":"Marin M","year":"2007","journal-title":"MMWR Recomm. 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