{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T13:30:30Z","timestamp":1793539830049,"version":"4.5.0"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"vor","delay-in-days":212,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Core\u2010needle biopsy (CNB) is used less frequently for the diagnosis of tumors in pediatric patients. In this report, the utility and safety of CNB for pediatric patients are described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The medical records of patients who underwent CNB at the Department of Pediatric Surgery, Kyushu University Hospital from April 2020 to November 2021 were retrospectively reviewed. A 14\u2009G or 16\u2009G BARDMISSION Disposable Needle Instrument was used. For the diagnosis of neuroblastoma, a 14\u2009G needle was selected; for the diagnosis of other tumors a 16\u2009G needle was selected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During the above period 17 CNBs were performed in 17 patients, and the median patient age was 8\u2009years (range, 15\u2009days\u201319\u2009years). The pathological diagnoses of the tumors were as follows: neuroblastoma,\n                      <jats:italic>n<\/jats:italic>\n                      = 6; lymphoma,\n                      <jats:italic>n<\/jats:italic>\n                      = 3; hepatoblastoma,\n                      <jats:italic>n<\/jats:italic>\n                      = 2; and others,\n                      <jats:italic>n<\/jats:italic>\n                      = 6. The quantity and quality of all tumor samples obtained by CNB was sufficient to make a diagnosis. The postoperative course after CNB was uneventful in most cases, with the exception of one case of hepatoblastoma (pseudoaneurysm).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Core\u2010needle biopsy is useful for pediatric patients. Sufficient tumor specimens were able to be obtained in all cases, irrespective of the type of tumor, and an accurate diagnosis could be made.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ped.15228","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T10:26:21Z","timestamp":1651227981000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The utility of core\u2010needle tumor biopsy for pediatric patients"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0010-4902","authenticated-orcid":false,"given":"Naonori","family":"Kawakubo","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery Graduate School of Medical Sciences Kyushu University  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junkichi","family":"Takemoto","sequence":"additional","affiliation":[{"name":"Department of Pediatric 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