{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T23:26:58Z","timestamp":1793575618086,"version":"4.5.0"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T00:00:00Z","timestamp":1672099200000},"content-version":"vor","delay-in-days":360,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2022,1]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Urinary tract infections (UTIs) caused by bacterial pathogens of the respiratory tract such as\n Streptococcus pneumoniae<\/jats:italic>\n ,\n Haemophilus influenzae<\/jats:italic>\n , and\n Moraxella catarrhalis<\/jats:italic>\n are rare and little is known about their clinical features and potential host risk factors. The aim of this study is to reveal their clinical characteristics.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We conducted a retrospective descriptive study on pediatric UTI due to\n S.\u00a0pneumoniae<\/jats:italic>\n ,\n Haemophilus<\/jats:italic>\n spp., or\n M.\u00a0catarrhalis<\/jats:italic>\n at a tertiary\u2010care pediatric hospital. Pediatric patients diagnosed with UTI between 2002 and 2020 were included. Patient demographics, laboratory data, and microbiological findings were extracted from their electronic medical records and the infectious disease surveillance system.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Among 46,332 urine samples, 76 bacteriuria (0.16%) and 22 UTI (0.05%) events due to the targeted species were identified (\n S.\u00a0pneumoniae, n<\/jats:italic>\n \u00a0=\u00a07, and\n Haemophilus<\/jats:italic>\n spp.,\n n<\/jats:italic>\n \u00a0=\u00a015). Of the patients, 17 (85%) had underlying urinary tract abnormalities and 13 (60%) had vesicocutaneous fistula. All the UTI episodes caused by\n S.\u00a0pneumoniae<\/jats:italic>\n and\n Haemophilus<\/jats:italic>\n spp. occurred after cystostomy. All the patients had satisfactory clinical outcomes.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Although\n S.\u00a0pneumoniae<\/jats:italic>\n and\n Haemophilus<\/jats:italic>\n spp. are rare causes of UTIs in children, they could be the true causative bacteria of UTI, particularly in the patients with urinary tract abnormalities and vesicocutaneous fistulas. Thus, clinicians should not ignore these pathogens as contaminations in special populations.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ped.15419","type":"journal-article","created":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T08:24:41Z","timestamp":1668587081000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Urinary tract infection caused by bacterial pathogens of the respiratory tract in children"],"prefix":"10.1111","volume":"64","author":[{"given":"Yoko Kobayashi","family":"Takahashi","sequence":"first","affiliation":[{"name":"Center for Postgraduate Education and Training National Center for Child Health and Development Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6598-5187","authenticated-orcid":false,"given":"Takanori","family":"Funaki","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medical Subspecialties National Center for Child Health and Development Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Ishiguro","sequence":"additional","affiliation":[{"name":"Center for Postgraduate Education and Training National Center for Child Health and Development Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3886-9089","authenticated-orcid":false,"given":"Isao","family":"Miyairi","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medical Subspecialties National Center for Child Health and Development Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30676-0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-0557"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-1330"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1701.100895"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2020.02.005"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2016.06.009"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-007-0531-1"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31829efdc4"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-4453(93)95160-K"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2012.11549.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2020.02.004"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-007-0283-7"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(14)70032-3"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70152-X"}],"container-title":["Pediatrics International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.15419","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ped.15419","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.15419","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T23:17:13Z","timestamp":1793575033000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ped.15419"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1111\/ped.15419"],"URL":"https:\/\/doi.org\/10.1111\/ped.15419","archive":["Portico"],"relation":{},"ISSN":["1328-8067","1442-200X"],"issn-type":[{"value":"1328-8067","type":"print"},{"value":"1442-200X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"2022-09-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e15419"}}