{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T10:23:02Z","timestamp":1792750982990,"version":"4.5.0"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T00:00:00Z","timestamp":1712016000000},"content-version":"vor","delay-in-days":92,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["21K08639"],"award-info":[{"award-number":["21K08639"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study aimed to reveal the early and late postoperative complications and outcomes after surgery for congenital biliary dilatation (CBD) by reviewing cases over the past 40\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively evaluated 59 patients with CBD who underwent radical surgery for complications and outcomes, based on medical records. Early complications were defined as those requiring treatment within 5\u2009years of the initial operation. Late complications were defined as those treated more than 5\u2009years later.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median age at the first surgery was 37\u2009months. Regarding biliary reconstruction, 54 of the 59 patients (91.5%) underwent hepaticojejunostomy. Although three patients underwent cholecystoduodenostomy and one patient underwent hepaticoduodenostomy, all were converted to hepaticojejunostomy after a median of 12.5\u2009years. One patient developed synchronous biliary carcinoma and underwent pancreaticoduodenectomy. Early complications occurred in seven patients with 10 events (surgical site infection,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093 bile leakage,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093; ileus,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093; bile duct obstruction,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091 and intussusception,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091). Late complications occurred in nine patients with 12 events (ileus,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093; anastomotic stricture,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093; hepatolithiasis,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093; asynchronous biliary carcinoma,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20092; pancreatolithiasis,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091). Two of the three patients with hepatolithiasis underwent hepatectomy refractory to the endoscopic approach. Two patients developed asynchronous biliary carcinoma at 34 and 13\u2009years after last operation; both ultimately died of the carcinoma. Only 35 patients (61.4%) underwent a follow\u2010up examination. A total of 11 female patients (45.8%) eventually married, and all successfully gave birth.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although the long\u2010term prognosis is excellent with complete cyst excision and hepaticojejunostomy, we emphasize the importance of long\u2010term follow\u2010up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ped.15712","type":"journal-article","created":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T09:52:31Z","timestamp":1712051551000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Early and late outcomes of congenital biliary dilatation in pediatric patients"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3034-693X","authenticated-orcid":false,"given":"Yoshiaki","family":"Takahashi","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery Niigata University Graduate School of Medical and Dental Sciences  Chuo\u2010Ku, Niigata City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Niigata University Graduate School of Medical and Dental Sciences  Chuo\u2010Ku, Niigata City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiaki","family":"Kinoshita","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Niigata University Graduate School of Medical and Dental Sciences  Chuo\u2010Ku, Niigata City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhki","family":"Arai","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Niigata University Graduate School of Medical and Dental Sciences  Chuo\u2010Ku, Niigata City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Ohyama","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Niigata University Graduate School of Medical and Dental Sciences  Chuo\u2010Ku, Niigata City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Yokota","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Niigata University Graduate School of Medical and Dental Sciences  Chuo\u2010Ku, Niigata City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Sugai","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Niigata University Graduate School of Medical and Dental Sciences  Chuo\u2010Ku, Niigata City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichi","family":"Takano","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Niigata University Graduate School of Medical and Dental Sciences  Chuo\u2010Ku, Niigata City 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