{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T14:25:21Z","timestamp":1774362321538,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"vor","delay-in-days":325,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Recent reports have demonstrated promising results regarding the use of ketamine sedation for reducing pediatric intussusception without an associated elevated risk of bowel perforation. However, data on direct intraluminal pressure are still lacking. This study aimed to investigate sedation safety, primarily by comparing intraluminal pressure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study included patients aged 10\u2009years or younger, diagnosed with intussusception at a university\u2010affiliated pediatric emergency department (ED) between July 2021 and February 2023. These patients were categorized into two groups: sedation and non\u2010sedation. During regular working hours (from 9:00\u2009a.m. to 5:00\u2009p.m. on weekdays), patients were administered 1\u2009mg\/kg of intravenous ketamine for sedation during air enema reduction. Patients within non\u2010working hours did not receive sedative interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In a study of 114 patients with intussusception (median age: 25\u2009months), 29 (25.4%) received sedatives, and 85 (74.6%) did not. Maximum intraluminal pressure during the procedure showed no significant difference between the groups (sedation: 64\u2009mmHg, non\u2010sedation: 83\u2009mmHg,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.091). Bowel perforation was not observed in the overall cohort. No difference was observed in the failure rate or recurrence rate within 24\u2009h between the two groups. Sedation with a median dose of 1\u2009mg\/kg ketamine did not cause delays in the ED process and demonstrated no adverse events while maintaining appropriate sedation depth with sequential dosing.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The utilization of ketamine sedation during fluoroscopy\u2010guided air enema reduction for pediatric intussusception was not associated with increased intraluminal pressure, increased rate of reduction failure, or bowel perforation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ped.15835","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T07:53:50Z","timestamp":1732175630000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Ketamine sedation during air enema reduction of pediatric intussusception: Assessing safety and intraluminal pressure"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4028-8155","authenticated-orcid":false,"given":"Jun Sung","family":"Park","sequence":"first","affiliation":[{"name":"Department of Pediatric Emergency Care Medicine, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dahyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatric Emergency Care Medicine, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Kyo","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Pediatric Emergency Care Medicine, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeeho","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pediatric Emergency Care Medicine, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4878-0929","authenticated-orcid":false,"given":"Seung Jun","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Emergency Care Medicine, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8720-8901","authenticated-orcid":false,"given":"Jong Seung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6854-3090","authenticated-orcid":false,"given":"Jeong\u2010Min","family":"Ryu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Choong Wook","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiology and Research Institute of Radiology, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pyeong Hwa","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology and Research Institute of Radiology, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee Mang","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Radiology and Research Institute of Radiology, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Ah","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Radiology and Research Institute of Radiology, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8471-901X","authenticated-orcid":false,"given":"Jeong\u2010Yong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatric Emergency Care Medicine, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,21]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"World Health Organization institutional repository for information sharing.Acute intussusception in infants and children: incidence clinical representation and management: a global perspective.2002World Health Organization Updated. 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