{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:57:42Z","timestamp":1790913462020,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"vor","delay-in-days":149,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2025,1]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Postoperative oral feeding difficulties in infants with congenital heart disease (\n CHD<\/jats:styled-content>\n ) are associated with prolonged hospital stays, increased readmission rates, and decreased patients' and their family's quality of life. They have recently been recognized as part of post\u2010intensive care syndrome in pediatrics. The purpose of this study was to identify the risk factors for acquired feeding difficulties after surgery for\n CHD<\/jats:styled-content>\n in infants. We hypothesized that infants who underwent more complex surgical procedures would be at higher risk.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We conducted a retrospective observational cohort study in a\n PICU<\/jats:styled-content>\n with 20 beds. Included were 124 eligible patients aged 1\u201311\u2009months, who had established oral feeding preoperatively and underwent surgery under cardiopulmonary bypass between 2018 and 2022. The primary outcome was the duration from surgery to the re\u2010establishment of oral feeding. We classified the patients into two groups according to the Society of Thoracic Surgeons \u2013 European Association for\n CardioThoracic<\/jats:styled-content>\n Surgery (\n STAT<\/jats:styled-content>\n ) mortality category.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Eighty\u2010one patients were classified as\n STAT<\/jats:styled-content>\n 1\u20132 (low) and 43 as\n STAT<\/jats:styled-content>\n 3\u20135 (high). The duration from surgery to re\u2010establishment of oral feeding was significantly longer in the high\u2010\n STAT<\/jats:styled-content>\n group in one minus Kaplan\u2013Meier curve estimate (\n p<\/jats:italic>\n \u2009=\u20090.016). In a multivariable Cox proportional hazards model analysis, longer operative time (\n HR<\/jats:styled-content>\n 0.83, 95%\n CI<\/jats:styled-content>\n 0.72\u20130.95,\n p<\/jats:italic>\n \u2009=\u20090.005) and higher\n STAT<\/jats:styled-content>\n (\n HR<\/jats:styled-content>\n 0.56, 95%\n CI<\/jats:styled-content>\n 0.32\u20130.95,\n p<\/jats:italic>\n \u2009=\u20090.032) were identified as significant risk factors for delayed oral feeding.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Longer operative times and procedures with higher\n STAT<\/jats:styled-content>\n categories may be associated with acquired feeding difficulties after surgery for\n CHD<\/jats:styled-content>\n in infants.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ped.70098","type":"journal-article","created":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T06:12:58Z","timestamp":1748585578000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Acquired feeding difficulties in infants after on\u2010pump cardiac surgery: A single\u2010center retrospective cohort study"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4343-8654","authenticated-orcid":false,"given":"Shin","family":"Tsubokura","sequence":"first","affiliation":[{"name":"Critical Care Medicine National Center for Child Health and Development Setagaya\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norihiko","family":"Tsuboi","sequence":"additional","affiliation":[{"name":"Critical Care Medicine National Center for Child Health and Development Setagaya\u2010ku Tokyo 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Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Critical Care Medicine National Center for Child Health and Development Setagaya\u2010ku Tokyo 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