{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:57:34Z","timestamp":1790913454198,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T00:00:00Z","timestamp":1759536000000},"content-version":"vor","delay-in-days":276,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The COVID\u201019 pandemic led to significant epidemiological shifts in various diseases due to reduced interpersonal contact. This study examined changes in pediatric intestinal intussusception incidence, a disease with unclear etiology, during the pandemic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Weekly intussusception cases in children \u226410\u2009years old in Seoul (2009\u20132022) were collected from the Health Insurance Review and Assessment Service (HIRA). Trends were analyzed using spline functions, and breakpoints were identified via student methods. Bayesian Structural Time Series (BSTS) models assessed incidence changes relative to predicted values. Cases were stratified by surgical intervention, and the complicated\u2010to\u2010uncomplicated case ratio was evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A sharp decline in intussusception incidence was observed around 2020, with breakpoints aligning with the first reported COVID\u201019 case. Post\u2010breakpoint, total cases decreased by 58.8% (95% CrI: \u221279.0%, 7.8%), with reductions of 62.4% (95% CrI: \u221278.9%, \u221220.2%) for uncomplicated cases and 51.1% (95% CrI: \u221262.6%, \u221233.8%) for complicated cases. The complicated\u2010to\u2010uncomplicated ratio increased by 43.3% (95% CrI: 13.0%, 87.1%). When analyzing only the post\u2010COVID\u201019 period, total and uncomplicated cases increased by 23.1% (95% CrI: 5.7%, 45.5%) from May 2022, but the change in ratio was not statistically significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pediatric intussusception incidence significantly declined following COVID\u201019 onset, supporting a link between disease occurrence and contact or infectious exposure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ped.70224","type":"journal-article","created":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T07:12:48Z","timestamp":1759561968000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Temporal trends in pediatric intestinal intussusception following the COVID\u201019 outbreak in Seoul, Korea"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4299-6411","authenticated-orcid":false,"given":"Jung Hee","family":"Hong","sequence":"first","affiliation":[{"name":"Department of Radiology Keimyung University College of Medicine  Daegu Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2822-8480","authenticated-orcid":false,"given":"Kiook","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine Dongguk University, College of Medicine  Gyeongju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-023-05210-x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0261332"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2022.37.e60"},{"issue":"3","key":"e_1_2_10_5_1","first-page":"E274","article-title":"Impact of the COVID\u201019 pandemic on the infectious disease epidemiology","volume":"64","author":"Facciola A","year":"2023","journal-title":"J Prev Med Hyg"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.4178\/epih.e2024081"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-021-02024-9"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1593429"},{"issue":"11","key":"e_1_2_10_9_1","article-title":"Decreased incidence of pediatric intussusception 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