{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:31:31Z","timestamp":1773012691816,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"vor","delay-in-days":39,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Clinical and radiological criteria for predicting surgical approach or spontaneous resolution have been evaluated mainly in primary non\u2010refluxing megaureters detected prenatally. We aimed to analyze these criteria in a retrospectively collected cohort of children with either prenatal or postnatal diagnosis of non\u2010obstructive non\u2010refluxing (NONR) megaureter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Hospital files of the children with NONR megaureter were evaluated retrospectively for age at diagnosis, presenting complaint, follow\u2010up period, accompanying urologic abnormalities, complications (renal scar and urinary tract infection), and final status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 27 NONR megaureters in 25 patients (male\/female: 19\/6; prenatal\/postnatal: 18\/7). Two prenatal cases had bilateral involvement. Spontaneous resolution rate in renal units was lower in postnatal cases than in prenatal cases (2 out of 7 vs. 15 out of 20, OR 7.5). Spontaneous resolution rate was also higher when ureteral diameter was &lt;11 versus \u226511\u2009mm (OR 10.9) and renal pelvis anteroposterior diameter \u226410\u2009mm versus &gt;10\u2009mm (OR 19.2). Surgical intervention rate was higher in the presence of ureteral diameter \u226514 versus &lt;14\u2009mm (OR 22.0). Renal units that underwent surgical treatment showed higher rates of febrile urinary tract infections, renal scarring, and reduced renal function on\n                      <jats:sup>99m<\/jats:sup>\n                      Tc\u2010MAG3 scintigraphy compared to those without surgical intervention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Initial management of asymptomatic non\u2010refluxing megaureters should be observational monitoring. Majority of them resolve spontaneously if ureteral diameter is &lt;11\u2009mm with renal pelvis anteroposterior diameter \u226410\u2009mm. However, children with ureteral diameter \u226514\u2009mm are prone to develop febrile urinary tract infection, renal scar, and decreased renal function requiring surgical intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ped.70323","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T12:27:26Z","timestamp":1770640046000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors associated with spontaneous resolution and surgery in non\u2010obstructive non\u2010refluxing megaureters"],"prefix":"10.1111","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9513-6661","authenticated-orcid":false,"given":"Gizem","family":"Yildiz","sequence":"first","affiliation":[{"name":"Department of Pediatric Nephrology Dokuz Eyl\u00fcl University Medical Faculty  Izmir Turkey"},{"name":"Department of Multidisciplinary Pediatric Kidney Transplantation Research Institute of Graduate Studies in Health Sciences, Istanbul University  Istanbul Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3760-7028","authenticated-orcid":false,"given":"Meral Torun","family":"Bayram","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology Dokuz Eyl\u00fcl University Medical Faculty  Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8428-7077","authenticated-orcid":false,"given":"Husne Didem","family":"Turker","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Dokuz Eyl\u00fcl University Medical Faculty  Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9959-881X","authenticated-orcid":false,"given":"Salih","family":"Kavukcu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology Dokuz Eyl\u00fcl University Medical Faculty  Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5901-7398","authenticated-orcid":false,"given":"Alper","family":"Soylu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology Dokuz Eyl\u00fcl University Medical Faculty  Izmir 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