{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T09:44:54Z","timestamp":1785750294497,"version":"3.56.0"},"reference-count":57,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T00:00:00Z","timestamp":1785715200000},"content-version":"vor","delay-in-days":214,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics International"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Treatment strategies for pediatric rheumatic diseases have changed substantially over the past two decades, driven by the development of biologics and cytokine\u2010targeted molecular therapy. Therapeutic approaches that modulate both innate and adaptive immune responses have improved prognosis in these immune\u2010mediated disorders, and early diagnosis with timely intervention is associated with better outcomes. However, affected children often present with non\u2010specific symptoms, and reliable biomarkers remain limited in juvenile idiopathic arthritis (JIA); thus, the diagnostic delay remains common. Imaging is an important adjunct in pediatric rheumatology; in selected scenarios, it can be pivotal for establishing a definitive diagnosis and for assessing disease subtype, complications, and treatment response. This review presents an imaging\u2010focused overview of pediatric rheumatic diseases. We begin with a brief review of current immunologic concepts, including the autoinflammatory\u2013autoimmune continuum, then illustrate typical imaging findings, discuss key differential diagnoses, and summarize the diagnostic strengths and limitations of major imaging modalities. We discuss in detail the major JIA subtypes based on the PRINTO classification, which aims to improve clinical coherence, facilitate risk stratification, and clarify relationships between pediatric and adult rheumatic entities. We also highlight interferonopathies\u2014disorders characterized by a type I interferon signature\u2014which provide a useful framework for understanding the mechanistic links between autoinflammation and autoimmunity along the continuum and for contextualizing selected autoimmune diseases, including systemic lupus erythematosus, juvenile dermatomyositis, and Sj\u00f6gren's syndrome.<\/jats:p>","DOI":"10.1111\/ped.70487","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T08:52:06Z","timestamp":1785747126000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Imaging Findings of Pediatric Rheumatic Disorders:\n                    <scp>JIA<\/scp>\n                    in the\n                    <scp>PRINTO<\/scp>\n                    Era and Autoimmune Interferonopathies"],"prefix":"10.1111","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1373-8277","authenticated-orcid":false,"given":"Yuko","family":"Tsujioka","sequence":"first","affiliation":[{"name":"Department of Radiology Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5842-5349","authenticated-orcid":false,"given":"Yoshitake","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Radiology Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0557-230X","authenticated-orcid":false,"given":"Gen","family":"Nishimura","sequence":"additional","affiliation":[{"name":"Department of Radiology Musashino\u2010Yowakai Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6807-4151","authenticated-orcid":false,"given":"Tatsuo","family":"Kono","sequence":"additional","affiliation":[{"name":"Department of Radiology Tokyo Metropolitan Children's Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8241-6565","authenticated-orcid":false,"given":"Masahiro","family":"Jinzaki","sequence":"additional","affiliation":[{"name":"Department of Radiology Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,3]]},"reference":[{"issue":"7","key":"e_1_2_15_2_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2023.103337","article-title":"A Comprehensive Overview of Juvenile Idiopathic Arthritis: From Pathophysiology to Management","volume":"22","author":"Bansal N.","year":"2023","journal-title":"Autoimmunity Reviews"},{"issue":"2","key":"e_1_2_15_3_1","first-page":"390","article-title":"International League of Associations for Rheumatology Classification of Juvenile Idiopathic Arthritis: Second Revision, Edmonton, 2001","volume":"31","author":"Petty R. E.","year":"2004","journal-title":"Journal of Rheumatology"},{"issue":"2","key":"e_1_2_15_4_1","doi-asserted-by":"crossref","first-page":"190","DOI":"10.3899\/jrheum.180168","article-title":"Toward New Classification Criteria for Juvenile Idiopathic Arthritis: First Steps, Pediatric Rheumatology International Trials Organization International Consensus","volume":"46","author":"Martini A.","year":"2019","journal-title":"Journal of Rheumatology"},{"key":"e_1_2_15_5_1","doi-asserted-by":"crossref","first-page":"38R","DOI":"10.1203\/PDR.0b013e31819dbd0a","article-title":"An Integrated Classification of Pediatric Inflammatory Diseases, Based on the Concepts of Autoinflammation and the Immunological Disease Continuum","volume":"65","author":"McGonagle D.","year":"2009","journal-title":"Pediatric Research"},{"issue":"7","key":"e_1_2_15_6_1","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/nrrheum.2011.68","article-title":"Pathogenesis of Systemic Juvenile Idiopathic Arthritis: Some Answers, More Questions","volume":"7","author":"Mellins E. D.","year":"2011","journal-title":"Nature Reviews Rheumatology"},{"issue":"7","key":"e_1_2_15_7_1","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1136\/ard-2022-222852","article-title":"EULAR Study Group on \u2018MHC\u2010I\u2010Opathy\u2019: Identifying Disease\u2010Overarching Mechanisms Across Disciplines and Borders","volume":"82","author":"Kuiper J. J.","year":"2023","journal-title":"Annals of the Rheumatic Diseases"},{"issue":"11","key":"e_1_2_15_8_1","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1007\/s11604-023-01447-6","article-title":"Imaging Findings of Juvenile Idiopathic Arthritis and Autoinflammatory Diseases in Children","volume":"41","author":"Tsujioka Y.","year":"2023","journal-title":"Japanese Journal of Radiology"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330\u2010017\u20104876\u2010y"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24757"},{"issue":"3","key":"e_1_2_15_11_1","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s00247-017-4000-0","article-title":"Temporomandibular Joint Atlas for Detection and Grading of Juvenile Idiopathic Arthritis Involvement by Magnetic Resonance Imaging","volume":"48","author":"Kellenberger C. J.","year":"2018","journal-title":"Pediatric Radiology"},{"issue":"12","key":"e_1_2_15_12_1","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.2147\/DDDT.S114532","article-title":"The Role of IL\u20101 Inhibition in Systemic Juvenile Idiopathic Arthritis: Current Status and Future Perspectives","volume":"8","author":"Toplak N.","year":"2018","journal-title":"Drug Design, Development and Therapy"},{"issue":"5","key":"e_1_2_15_13_1","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1136\/annrheumdis-2016-210324","article-title":"Genetic Architecture Distinguishes Systemic Juvenile Idiopathic Arthritis From Other Forms of Juvenile Idiopathic Arthritis: Clinical and Therapeutic Implications","volume":"76","author":"Ombrello M. J.","year":"2017","journal-title":"Annals of the Rheumatic Diseases"},{"issue":"11","key":"e_1_2_15_14_1","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1002\/art.41073","article-title":"Systemic Juvenile Idiopathic Arthritis\u2010Associated Lung Disease: Characterization and Risk Factors","volume":"71","author":"Schulert G. S.","year":"2019","journal-title":"Arthritis & Rhematology"},{"issue":"12","key":"e_1_2_15_15_1","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1136\/annrheumdis-2019-216040","article-title":"Emergent High Fatality Lung Disease in Systemic Juvenile Arthritis","volume":"78","author":"Saper V. E.","year":"2019","journal-title":"Annals of the Rheumatic Diseases"},{"issue":"12","key":"e_1_2_15_16_1","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.3390\/diagnostics12123095","article-title":"Lung Involvement in Systemic Juvenile Idiopathic Arthritis: A Narrative Review","volume":"12","author":"Petrongari D.","year":"2022","journal-title":"Diagnostics (Basel)"},{"issue":"10","key":"e_1_2_15_17_1","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1002\/acr2.11600","article-title":"Development of a Screening Algorithm for Lung Disease in Systemic Juvenile Idiopathic Arthritis","volume":"5","author":"Wobma H.","year":"2023","journal-title":"ACR Open Rheumatology"},{"issue":"9","key":"e_1_2_15_18_1","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.3899\/jrheum.150997","article-title":"The Systemic Juvenile Idiopathic Arthritis Cohort of the Childhood Arthritis and Rheumatology Research Alliance Registry: 2010\u20132013","volume":"43","author":"Janow G.","year":"2016","journal-title":"Journal of Rheumatology"},{"key":"e_1_2_15_19_1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jaut.2015.08.002","article-title":"Immunogenetics of Juvenile Idiopathic Arthritis: A Comprehensive Review","volume":"64","author":"Hersh A. O.","year":"2015","journal-title":"Journal of Autoimmunity"},{"issue":"10","key":"e_1_2_15_20_1","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1136\/annrheumdis-2014-205372","article-title":"The Outcomes of Juvenile Idiopathic Arthritis in Children Managed With Contemporary Treatments: Results From the ReACCh\u2010Out Cohort","volume":"74","author":"Guzman J.","year":"2015","journal-title":"Annals of the Rheumatic Diseases"},{"issue":"2","key":"e_1_2_15_21_1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/acr.22665","article-title":"Assessment of Sacroiliitis at Diagnosis of Juvenile Spondyloarthritis by Radiography, Magnetic Resonance Imaging, and Clinical Examination","volume":"68","author":"Weiss P. F.","year":"2016","journal-title":"Arthritis Care & Research (Hoboken)"},{"issue":"9","key":"e_1_2_15_22_1","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.3899\/jrheum.181115","article-title":"Preliminary Definitions for Sacroiliac Joint Pathologies in the OMERACT Juvenile Idiopathic Arthritis Magnetic Resonance Imaging Score (OMERACT JAMRIS\u2010SIJ)","volume":"46","author":"Otobo T. M.","year":"2019","journal-title":"Journal of Rheumatology"},{"issue":"4","key":"e_1_2_15_23_1","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1093\/mr\/roaf034","article-title":"Pearls and Pitfalls in Imaging of Axial Spondyloarthritis for Rheumatologists","volume":"35","author":"Nozaki T.","year":"2025","journal-title":"Modern Rheumatology"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067\u2010025\u201007340\u2010z"},{"issue":"1","key":"e_1_2_15_25_1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s12969-021-00629-8","article-title":"Juvenile Idiopathic Arthritis: From Aetiopathogenesis to Therapeutic Approaches","volume":"19","author":"Zaripova L. N.","year":"2021","journal-title":"Pediatric Rheumatology Online Journal"},{"issue":"6","key":"e_1_2_15_26_1","doi-asserted-by":"crossref","first-page":"2896","DOI":"10.1093\/rheumatology\/keaa733","article-title":"A Clinical Prediction Model for Estimating the Risk of Developing Uveitis in Patients With Juvenile Idiopathic Arthritis","volume":"60","author":"Straalen J. W.","year":"2021","journal-title":"Rheumatology (Oxford, England)"},{"issue":"7","key":"e_1_2_15_27_1","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1007\/s11604-020-00953-1","article-title":"Imaging Features in Patients With SAPHO\/CRMO: A Pictorial Review","volume":"38","author":"Himuro H.","year":"2020","journal-title":"Japanese Journal of Radiology"},{"issue":"7","key":"e_1_2_15_28_1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1038\/nri3850","article-title":"Aicardi\u2013Gouti\u00e8res Syndrome and the Type I Interferonopathies","volume":"15","author":"Crow Y. J.","year":"2015","journal-title":"Nature Reviews. Immunology"},{"key":"e_1_2_15_29_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2022.108953","article-title":"Systemic Lupus Erythematosus as a Genetic Disease","volume":"236","author":"Harley I. T. W.","year":"2022","journal-title":"Clinical Immunology"},{"issue":"10","key":"e_1_2_15_30_1","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1002\/acr.22591","article-title":"Diagnosis, Monitoring, and Treatment of Systemic Lupus Erythematosus: A Systematic Review of Clinical Practice Guidelines: SLE Treatment Guidelines","volume":"67","author":"Tunnicliffe D. J.","year":"2015","journal-title":"Arthritis Care & Research"},{"issue":"11","key":"e_1_2_15_31_1","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1007\/s11604-021-01154-0","article-title":"Diffusion Tensor Imaging of Renal Cortex in Lupus Nephritis","volume":"39","author":"Razek A. A. K. A.","year":"2021","journal-title":"Japanese Journal of Radiology"},{"issue":"4","key":"e_1_2_15_32_1","doi-asserted-by":"crossref","first-page":"715","DOI":"10.3346\/jkms.2009.24.4.715","article-title":"Clinical Characteristics and Outcomes of Juvenile and Adult Dermatomyositis","volume":"24","author":"Na S.\u2010J.","year":"2009","journal-title":"Journal of Korean Medical Science"},{"issue":"5","key":"e_1_2_15_33_1","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1080\/14397595.2018.1511026","article-title":"Clinical Significance of Subcutaneous Fat and Fascial Involvement in Juvenile Dermatomyositis","volume":"29","author":"Sakurai N.","year":"2019","journal-title":"Modern Rheumatology"},{"issue":"2","key":"e_1_2_15_34_1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1097\/MD.0b013e31816bc604","article-title":"Predictors of Acquired Lipodystrophy in Juvenile\u2010Onset Dermatomyositis and a Gradient of Severity","volume":"87","author":"Bingham A.","year":"2008","journal-title":"Medicine (Baltimore)"},{"issue":"6","key":"e_1_2_15_35_1","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1038\/s41390-024-03551-3","article-title":"Profile of Patients With Juvenile Dermatomyositis and Anti\u2010MDA5 Autoantibodies","volume":"97","author":"Vignesh P.","year":"2025","journal-title":"Pediatric Research"},{"issue":"9","key":"e_1_2_15_36_1","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1007\/s11604-024-01603-6","article-title":"Childhood Interstitial Lung Diseases: Current Understanding of the Classification and Imaging Findings","volume":"42","author":"Tsujioka Y.","year":"2024","journal-title":"Japanese Journal of Radiology"},{"issue":"10","key":"e_1_2_15_37_1","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1007\/s11604-024-01607-2","article-title":"Correlation of CT\u2010Based Radiomics Analysis With Pathological Cellular Infiltration in Fibrosing Interstitial Lung Diseases","volume":"42","author":"Haga A.","year":"2024","journal-title":"Japanese Journal of Radiology"},{"issue":"3","key":"e_1_2_15_38_1","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1093\/rheumatology\/kead263","article-title":"A Nomogram Based on Clinical Factors and CT Radiomics for Predicting Anti\u2010MDA5+ DM Complicated by RP\u2010ILD","volume":"63","author":"Li Y.","year":"2024","journal-title":"Rheumatology (Oxford, England)"},{"issue":"1","key":"e_1_2_15_39_1","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1186\/s12887-025-05968-z","article-title":"Application of HRCT\u2010Based Radiomics to Predict Interstitial Lung Disease for Juvenile Dermatomyositis","volume":"25","author":"Liu L.","year":"2025","journal-title":"BMC Pediatrics"},{"issue":"5","key":"e_1_2_15_40_1","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1093\/rheumatology\/kex490","article-title":"Systemic Interferon Type I and Type II Signatures in Primary Sj\u00f6gren's Syndrome Reveal Differences in Biological Disease Activity","volume":"57","author":"Bodewes I. L. A.","year":"2018","journal-title":"Rheumatology (Oxford, England)"},{"issue":"2","key":"e_1_2_15_41_1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.3390\/biom11020251","article-title":"The Role of Interferons in the Pathogenesis of Sj\u00f6gren's Syndrome and Future Therapeutic Perspectives","volume":"11","author":"Del Papa N.","year":"2021","journal-title":"Biomolecules"},{"issue":"4","key":"e_1_2_15_42_1","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.rdc.2021.07.008","article-title":"Unique Aspects of Pediatric Sj\u00f6gren Disease","volume":"47","author":"Randell R. L.","year":"2021","journal-title":"Rheumatic Diseases Clinics of North America"},{"issue":"5","key":"e_1_2_15_43_1","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1093\/rheumatology\/keab560","article-title":"Comparison of Salivary Gland MRI and Ultrasonography Findings Among Patients With Sj\u00f6gren's Syndrome Over a Wide Age Range","volume":"61","author":"Takagi Y.","year":"2022","journal-title":"Rheumatology (Oxford, England)"},{"issue":"1","key":"e_1_2_15_44_1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/s11604-023-01479-y","article-title":"Developing Standards for MRI Evaluation of Joints in Children With Juvenile Idiopathic Arthritis Utilizing the Temporomandibular Joint as a Model","volume":"42","author":"Navallas M.","year":"2024","journal-title":"Japanese Journal of Radiology"},{"issue":"11","key":"e_1_2_15_45_1","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1007\/s11604-023-01453-8","article-title":"3D T1rho Sequences With FASE, UTE, and MAPSS Acquisitions for Knee Evaluation","volume":"41","author":"Bae W. C.","year":"2023","journal-title":"Japanese Journal of Radiology"},{"issue":"3","key":"e_1_2_15_46_1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s00247-019-04557-4","article-title":"T1\u03c1\u2010Mapping for Assessing Knee Joint Cartilage in Children With Juvenile Idiopathic Arthritis\u2014Feasibility and Repeatability","volume":"50","author":"Barendregt A. M.","year":"2020","journal-title":"Pediatric Radiology"},{"issue":"11","key":"e_1_2_15_47_1","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1007\/s11604-023-01449-4","article-title":"Magnetic Resonance Bone Imaging: Applications to Vertebral Lesions","volume":"41","author":"Tsuchiya K.","year":"2023","journal-title":"Japanese Journal of Radiology"},{"issue":"9","key":"e_1_2_15_48_1","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.crad.2021.05.015","article-title":"Clinical Application of Ultrashort Echo\u2010Time MRI for Lung Pathologies in Children","volume":"76","author":"Geiger J.","year":"2021","journal-title":"Clinical Radiology"},{"issue":"3","key":"e_1_2_15_49_1","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1007\/s00330-021-08236-7","article-title":"Ultrashort Echo Time MRI of the Lung in Children and Adolescents: Comparison With Non\u2010Enhanced Computed Tomography and Standard Post\u2010Contrast T1w MRI Sequences","volume":"32","author":"Renz D. M.","year":"2022","journal-title":"European Radiology"},{"issue":"6","key":"e_1_2_15_50_1","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s11604-025-01735-3","article-title":"Recent Trends in Scientific Research in Chest Radiology: What to Do or Not to Do? That Is the Critical Question in Research","volume":"43","author":"Hatabu H.","year":"2025","journal-title":"Japanese Journal of Radiology"},{"issue":"3","key":"e_1_2_15_51_1","first-page":"355","article-title":"Advancing Clinical MRI Exams With Artificial Intelligence: Japan's Contributions and Future Prospects","volume":"43","author":"Fujita S.","year":"2025","journal-title":"Japanese Journal of Radiology"},{"issue":"1","key":"e_1_2_15_52_1","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/s11604-024-01620-5","article-title":"Selection of the Phase of Dynamic Contrast\u2010Enhanced Magnetic Resonance Imaging and Use of the Voxel\u2010Based Enhancement Maps May Facilitate the Assessment of Clinical Disease Activity in Patients With Rheumatoid Arthritis","volume":"43","author":"Mori Y.","year":"2025","journal-title":"Japanese Journal of Radiology"},{"issue":"10","key":"e_1_2_15_53_1","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1007\/s11604-024-01592-6","article-title":"Fully Automatic Quantification for Hand Synovitis in Rheumatoid Arthritis Using Pixel\u2010Classification\u2010Based Segmentation Network in DCE\u2010MRI","volume":"42","author":"Fang W.","year":"2024","journal-title":"Japanese Journal of Radiology"},{"issue":"7","key":"e_1_2_15_54_1","doi-asserted-by":"crossref","first-page":"3051","DOI":"10.21037\/qims-20-1158","article-title":"Improving the Image Quality of Pediatric Chest CT Angiography With Low Radiation Dose and Contrast Volume Using Deep Learning Image Reconstruction","volume":"11","author":"Sun J.","year":"2021","journal-title":"Quantitative Imaging in Medicine and Surgery"},{"issue":"1","key":"e_1_2_15_55_1","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1148\/radiol.2020202317","article-title":"Improving Image Quality and Reducing Radiation Dose for Pediatric CT by Using Deep Learning Reconstruction","volume":"298","author":"Brady S. L.","year":"2021","journal-title":"Radiology"},{"issue":"7","key":"e_1_2_15_56_1","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1007\/s11604-022-01259-0","article-title":"Unenhanced Abdominal Low\u2010Dose CT Reconstructed With Deep Learning\u2010Based Image Reconstruction: Image Quality and Anatomical Structure Depiction","volume":"40","author":"Kaga T.","year":"2022","journal-title":"Japanese Journal of Radiology"},{"issue":"2","key":"e_1_2_15_57_1","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/s11604-024-01666-5","article-title":"Accelerating FLAIR Imaging via Deep Learning Reconstruction: Potential for Evaluating White Matter Hyperintensities","volume":"43","author":"Nishioka N.","year":"2025","journal-title":"Japanese Journal of Radiology"},{"issue":"1","key":"e_1_2_15_58_1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s00234-022-03053-1","article-title":"Deep Learning Reconstruction in Pediatric Brain MRI: Comparison of Image Quality With Conventional T2\u2010Weighted MRI","volume":"65","author":"Kim S.\u2010H.","year":"2023","journal-title":"Neuroradiology"}],"container-title":["Pediatrics International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.70487","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ped.70487","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ped.70487","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T08:52:13Z","timestamp":1785747133000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ped.70487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":57,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/ped.70487"],"URL":"https:\/\/doi.org\/10.1111\/ped.70487","archive":["Portico"],"relation":{},"ISSN":["1328-8067","1442-200X"],"issn-type":[{"value":"1328-8067","type":"print"},{"value":"1442-200X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-03-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70487"}}