{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T12:19:23Z","timestamp":1789820363547,"version":"4.0.1"},"reference-count":128,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,10,14]],"date-time":"2013-10-14T00:00:00Z","timestamp":1381708800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"},{"start":{"date-parts":[[2013,10,14]],"date-time":"2013-10-14T00:00:00Z","timestamp":1381708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"funder":[{"name":"Robert Wood Johnson Harold Amos Medical Faculty Program"},{"DOI":"10.13039\/100009340","name":"Children's Discovery Institute","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100009340","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100001068","name":"Dana Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100001068","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["DK-64832"],"award-info":[{"award-number":["DK-64832"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["UL1-RR-024992"],"award-info":[{"award-number":["UL1-RR-024992"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Diabetes"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1111\/pedi.12088","type":"journal-article","created":{"date-parts":[[2013,10,14]],"date-time":"2013-10-14T07:52:45Z","timestamp":1381737165000},"page":"541-553","source":"Crossref","is-referenced-by-count":69,"title":["Glycemic extremes in youth with T1DM: The structural and functional integrity of the developing brain"],"prefix":"10.1155","volume":"14","author":[{"given":"Ana Maria","family":"Arbelaez","sequence":"first","affiliation":[{"name":"Department of Pediatrics; Washington University School of Medicine; St. Louis MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Semenkovich","sequence":"additional","affiliation":[{"name":"Department of Pediatrics; Washington University School of Medicine; St. Louis MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara","family":"Hershey","sequence":"additional","affiliation":[{"name":"Department of Psychiatry; Washington University School of Medicine; St. Louis MO USA"},{"name":"Department of Neurology; Washington University School of Medicine; St. Louis MO USA"},{"name":"Department of Radiology; Washington University School of Medicine; St. Louis MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,14]]},"reference":[{"key":"10.1111\/pedi.12088-BIB0001|pedi12088-cit-0001","first-page":"R203","article-title":"Ratio of central nervous system to body metabolism in vertebrates: its constancy and functional basis","volume":"241","author":"Mink","year":"1981","journal-title":"Am J Physiol"},{"key":"10.1111\/pedi.12088-BIB0002|pedi12088-cit-0002","first-page":"637","volume-title":"Basic Neurochemistry Molecular, Cellular and Medical Aspects","author":"Clarke","year":"1999","edition":"6"},{"key":"10.1111\/pedi.12088-BIB0003|pedi12088-cit-0003","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.neuron.2007.11.008","article-title":"Inhibition and brain work","volume":"56","author":"Buzsaki","year":"2007","journal-title":"Neuron"},{"key":"10.1111\/pedi.12088-BIB0004|pedi12088-cit-0004","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1053\/sp.2000.6361","article-title":"Glucose metabolism in the developing brain","volume":"24","author":"Vannucci","year":"2000","journal-title":"Semin Perinatol"},{"key":"10.1111\/pedi.12088-BIB0005|pedi12088-cit-0005","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1146\/annurev-cellbio-092910-154237","article-title":"Aerobic glycolysis: meeting the metabolic requirements of cell proliferation","volume":"27","author":"Lunt","year":"2011","journal-title":"Annu Rev Cell Dev Biol"},{"key":"10.1111\/pedi.12088-BIB0006|pedi12088-cit-0006","doi-asserted-by":"crossref","first-page":"13281","DOI":"10.1073\/pnas.1105108108","article-title":"Extraordinary neoteny of synaptic spines in the human prefrontal cortex","volume":"108","author":"Petanjek","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1111\/pedi.12088-BIB0007|pedi12088-cit-0007","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.neubiorev.2004.03.002","article-title":"The selfish brain: competition for energy resources","volume":"28","author":"Peters","year":"2004","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1111\/pedi.12088-BIB0008|pedi12088-cit-0008","first-page":"63","article-title":"Neuropathologic findings in three cases of profound hypoglycemia","volume":"8","author":"Auer","year":"1989","journal-title":"Clin Neuropathol"},{"key":"10.1111\/pedi.12088-BIB0009|pedi12088-cit-0009","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1203\/01.PDR.0000110523.07240.C1","article-title":"Repetitive hypoglycemia in young rats impairs hippocampal long-term potentiation","volume":"55","author":"Yamada","year":"2004","journal-title":"Pediatr Res"},{"key":"10.1111\/pedi.12088-BIB0010|pedi12088-cit-0010","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1007\/s11064-012-0789-y","article-title":"Effects of fluctuating glucose levels on neuronal cells in vitro","volume":"37","author":"Russo","year":"2012","journal-title":"Neurochem Res"},{"key":"10.1111\/pedi.12088-BIB0011|pedi12088-cit-0011","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/nrn2294","article-title":"Glucose neurotoxicity","volume":"9","author":"Tomlinson","year":"2008","journal-title":"Nat Rev Neurosci"},{"key":"10.1111\/pedi.12088-BIB0012|pedi12088-cit-0012","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1053\/j.sempedsurg.2010.10.005","article-title":"Glucose metabolism and neurological outcome in congenital hyperinsulinism","volume":"20","author":"Ludwig","year":"2011","journal-title":"Semin Pediatr Surg"},{"key":"10.1111\/pedi.12088-BIB0013|pedi12088-cit-0013","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1111\/dmcn.12045","article-title":"Topography of brain damage in metabolic hypoglycaemia is determined by age at which hypoglycaemia occurred","volume":"55","author":"Gataullina","year":"2013","journal-title":"Dev Med Child Neurol"},{"key":"10.1111\/pedi.12088-BIB0014|pedi12088-cit-0014","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1076\/chin.10.1.36.26241","article-title":"Neurocognitive correlates of type 1 diabetes mellitus in childhood","volume":"10","author":"Desrocher","year":"2004","journal-title":"Child Neuropsychol"},{"key":"10.1111\/pedi.12088-BIB0015|pedi12088-cit-0015","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1651-2227.1966.tb15222.x","article-title":"Childhood diabetic neuropathy: a clinical and neuropsychological study","volume":"55","author":"Eeg-Olofsson","year":"1966","journal-title":"Acta Pediatrica Scandinavica"},{"issue":"Suppl. 11","key":"10.1111\/pedi.12088-BIB0016|pedi12088-cit-0016","first-page":"51","article-title":"Hypoglycaemia-Clinical consequences and morbidity","volume":"3","author":"Frier","year":"2001","journal-title":"Int J Clin Psychol"},{"key":"10.1111\/pedi.12088-BIB0017|pedi12088-cit-0017","doi-asserted-by":"crossref","first-page":"89","DOI":"10.2337\/diacare.12.2.89","article-title":"Longitudinal relationship of asymptomatic hypoglycemia to cognitive function in IDDM","volume":"12","author":"Golden","year":"1989","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0018|pedi12088-cit-0018","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0022-3476(95)70542-2","article-title":"Effects of acute hyperglycemia on mental efficiency and counterregulatory hormones in adolescents with insulin-dependent diabetes mellitus","volume":"126","author":"Gschwend","year":"1995","journal-title":"J Pediatr"},{"key":"10.1111\/pedi.12088-BIB0019|pedi12088-cit-0019","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.2337\/diacare.22.8.1318","article-title":"Conventional versus intensive diabetes therapy in children with type 1 diabetes: effects on memory and motor speed","volume":"22","author":"Hershey","year":"1999","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0020|pedi12088-cit-0020","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1017\/S1355617797005092","article-title":"Memory and insulin dependent diabetes mellitus (IDDM): effects of childhood onset and severe hypoglycemia","volume":"3","author":"Hershey","year":"1997","journal-title":"J Int Neuropsychol Soc"},{"key":"10.1111\/pedi.12088-BIB0021|pedi12088-cit-0021","doi-asserted-by":"crossref","first-page":"557","DOI":"10.2337\/diab.41.5.557","article-title":"The impact of diabetes on the CNS","volume":"41","author":"McCall","year":"1992","journal-title":"Diabetes"},{"key":"10.1111\/pedi.12088-BIB0022|pedi12088-cit-0022","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1111\/j.1399-5448.2009.00618.x","article-title":"Neurocognitive functioning in preschool-age children with type 1 diabetes mellitus","volume":"11","author":"Patino-Fernandez","year":"2010","journal-title":"Pediatr Diabetes"},{"key":"10.1111\/pedi.12088-BIB0023|pedi12088-cit-0023","volume-title":"Pediatric Neuropsychology: Research, Theory and Practice","author":"Rovet","year":"1999"},{"key":"10.1111\/pedi.12088-BIB0024|pedi12088-cit-0024","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1542\/peds.75.5.921","article-title":"Cognitive deficits in adolescents who developed diabetes early in life","volume":"75","author":"Ryan","year":"1985","journal-title":"Pediatrics"},{"key":"10.1111\/pedi.12088-BIB0025|pedi12088-cit-0025","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1007\/s00125-006-0392-3","article-title":"Diabetes and brain damage: more (or less) than meets the eye?","volume":"49","author":"Ryan","year":"2006","journal-title":"Diabetologia"},{"key":"10.1111\/pedi.12088-BIB0026|pedi12088-cit-0026","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.2337\/dc07-0351","article-title":"Regional brain volume differences associated with hyperglycemia and severe hypoglycemia in youth with type 1 diabetes","volume":"30","author":"Perantie","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0027|pedi12088-cit-0027","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.2337\/dc06-1637","article-title":"Brain imaging in patients with diabetes a systematic review","volume":"29","author":"Harten","year":"2006","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0028|pedi12088-cit-0028","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.ejphar.2007.11.085","article-title":"Structural brain imaging in diabetes a methodological perspective","volume":"585","author":"Jongen","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1111\/pedi.12088-BIB0029|pedi12088-cit-0029","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1210\/er.2007-0034","article-title":"Cognitive dysfunction and diabetes mellitus","volume":"29","author":"Kodl","year":"2008","journal-title":"Endocr Rev"},{"key":"10.1111\/pedi.12088-BIB0030|pedi12088-cit-0030","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/ncpneuro0097","article-title":"Therapy insight: the impact of type 1 diabetes on brain development and function","volume":"2","author":"Northam","year":"2006","journal-title":"Nat Clin Pract Neurol"},{"key":"10.1111\/pedi.12088-BIB0031|pedi12088-cit-0031","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1093\/brain\/98.1.81","article-title":"The density of synapses and neurons in normal, mentally defective ageing human brains","volume":"98","author":"Cragg","year":"1975","journal-title":"Brain"},{"key":"10.1111\/pedi.12088-BIB0032|pedi12088-cit-0032","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0304-3940(82)90379-2","article-title":"Synaptogenesis in human visual cortex--evidence for synapse elimination during normal development","volume":"33","author":"Huttenlocher","year":"1982","journal-title":"Neurosci Lett"},{"key":"10.1111\/pedi.12088-BIB0033|pedi12088-cit-0033","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/cne.901760203","article-title":"Development of neurons in the visual cortex (area 17) of the monkey (Macaca nemestrina) a Golgi study from fetal day 127 to postnatal maturity","volume":"176","author":"Lund","year":"1977","journal-title":"J Comp Neurol"},{"key":"10.1111\/pedi.12088-BIB0034|pedi12088-cit-0034","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1126\/science.3952506","article-title":"Concurrent overproduction of synapses in diverse regions of the primate cerebral cortex","volume":"232","author":"Rakic","year":"1986","journal-title":"Science"},{"key":"10.1111\/pedi.12088-BIB0035|pedi12088-cit-0035","article-title":"Trends and properties of human cerebral cortex: correlations with cortical myelin content","author":"Glasser","year":"2013","journal-title":"Neuroimage"},{"key":"10.1111\/pedi.12088-BIB0036|pedi12088-cit-0036","doi-asserted-by":"crossref","first-page":"11597","DOI":"10.1523\/JNEUROSCI.2180-11.2011","article-title":"Mapping human cortical areas in vivo based on myelin content as revealed by T1- and T2-weighted MRI","volume":"31","author":"Glasser","year":"2011","journal-title":"J Neurosci"},{"key":"10.1111\/pedi.12088-BIB0037|pedi12088-cit-0037","doi-asserted-by":"crossref","first-page":"2852","DOI":"10.1093\/cercor\/bhq035","article-title":"Longitudinal analysis of neural network development in preterm infants","volume":"20","author":"Smyser","year":"2010","journal-title":"Cereb Cortex"},{"key":"10.1111\/pedi.12088-BIB0038|pedi12088-cit-0038","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1016\/j.neuroimage.2012.02.018","article-title":"The Human Connectome Project a data acquisition perspective","volume":"62","author":"Van Essen","year":"2012","journal-title":"Neuroimage"},{"key":"10.1111\/pedi.12088-BIB0039|pedi12088-cit-0039","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1002\/ana.410220408","article-title":"Positron emission tomography study of human brain functional development","volume":"22","author":"Chugani","year":"1987","journal-title":"Ann Neurol"},{"key":"10.1111\/pedi.12088-BIB0040|pedi12088-cit-0040","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1172\/JCI103509","article-title":"An adaptation of the nitrous oxide method to the study of the cerebral circulation in children; normal values for cerebral blood flow and cerebral metabolic rate in childhood","volume":"36","author":"Kennedy","year":"1957","journal-title":"J Clin Invest"},{"key":"10.1111\/pedi.12088-BIB0041|pedi12088-cit-0041","first-page":"917","article-title":"Developmental changes of cerebral blood flow and oxygen metabolism in children","volume":"20","author":"Takahashi","year":"1999","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1111\/pedi.12088-BIB0042|pedi12088-cit-0042","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1196\/annals.1308.009","article-title":"Structural magnetic resonance imaging of the adolescent brain","volume":"1021","author":"Giedd","year":"2004","journal-title":"Ann N Y Acad Sci"},{"issue":"Pt 5","key":"10.1111\/pedi.12088-BIB0043|pedi12088-cit-0043","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1093\/brain\/119.5.1763","article-title":"Brain development, gender and IQ in children. A volumetric imaging study","volume":"119","author":"Reiss","year":"1996","journal-title":"Brain"},{"key":"10.1111\/pedi.12088-BIB0044|pedi12088-cit-0044","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1093\/cercor\/bhp118","article-title":"Brain maturation in adolescence and young adulthood: regional age-related changes in cortical thickness and white matter volume and microstructure","volume":"20","author":"Tamnes","year":"2010","journal-title":"Cereb Cortex"},{"key":"10.1111\/pedi.12088-BIB0045|pedi12088-cit-0045","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.neuron.2010.08.040","article-title":"Structural MRI of pediatric brain development: what have we learned and where are we going?","volume":"67","author":"Giedd","year":"2010","journal-title":"Neuron"},{"key":"10.1111\/pedi.12088-BIB0046|pedi12088-cit-0046","doi-asserted-by":"crossref","first-page":"7174","DOI":"10.1523\/JNEUROSCI.0054-11.2011","article-title":"How does your cortex grow?","volume":"31","author":"Raznahan","year":"2011","journal-title":"J Neurosci"},{"issue":"Suppl. 12","key":"10.1111\/pedi.12088-BIB0047|pedi12088-cit-0047","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1399-5448.2009.00568.x","article-title":"Definition, epidemiology and classification of diabetes in children and adolescents","volume":"10","author":"Craig","year":"2009","journal-title":"Pediatr Diabetes"},{"key":"10.1111\/pedi.12088-BIB0048|pedi12088-cit-0048","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.2337\/diacare.28.10.2372","article-title":"Frequency and timing of severe hypoglycemia affects spatial memory in children with type 1 diabetes","volume":"28","author":"Hershey","year":"2005","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0049|pedi12088-cit-0049","doi-asserted-by":"crossref","first-page":"513","DOI":"10.2337\/dc11-1290","article-title":"Age-related loss of brain volume and T2 relaxation time in youth with type 1 diabetes","volume":"35","author":"Pell","year":"2012","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0050|pedi12088-cit-0050","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1172\/JCI118226","article-title":"Overexpression of glucose transporters in rat mesangial cells cultured in a normal glucose milieu mimics the diabetic phenotype","volume":"96","author":"Heilig","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1111\/pedi.12088-BIB0051|pedi12088-cit-0051","doi-asserted-by":"crossref","first-page":"80","DOI":"10.2337\/diab.42.1.80","article-title":"Differential regulation of glucose transport and transporters by glucose in vascular endothelial and smooth muscle cells","volume":"42","author":"Kaiser","year":"1993","journal-title":"Diabetes"},{"key":"10.1111\/pedi.12088-BIB0052|pedi12088-cit-0052","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1126\/science.2996146","article-title":"Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist","volume":"230","author":"Wieloch","year":"1985","journal-title":"Science"},{"key":"10.1111\/pedi.12088-BIB0053|pedi12088-cit-0053","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1023\/A:1007563104170","article-title":"Is neuronal injury caused by hypoglycemic coma of the necrotic or apoptotic type?","volume":"25","author":"Ouyang","year":"2000","journal-title":"Neurochem Res"},{"key":"10.1111\/pedi.12088-BIB0054|pedi12088-cit-0054","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1002\/jnr.10791","article-title":"Systemic insulin-like growth factor-I administration prevents cognitive impairment in diabetic rats, and brain IGF regulates learning\/memory in normal adult rats","volume":"74","author":"Lupien","year":"2003","journal-title":"J Neurosci Res"},{"key":"10.1111\/pedi.12088-BIB0055|pedi12088-cit-0055","doi-asserted-by":"crossref","first-page":"929","DOI":"10.2337\/diabetes.55.04.06.db05-1325","article-title":"Increased brain monocarboxylic acid transport and utilization in type 1 diabetes","volume":"55","author":"Mason","year":"2006","journal-title":"Diabetes"},{"key":"10.1111\/pedi.12088-BIB0056|pedi12088-cit-0056","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ejphar.2004.02.056","article-title":"Insulin, C-peptide, hyperglycemia, and central nervous system complications in diabetes","volume":"490","author":"Sima","year":"2004","journal-title":"Eur J Pharmacol"},{"key":"10.1111\/pedi.12088-BIB0057|pedi12088-cit-0057","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1034\/j.1399-5448.2003.00025.x","article-title":"Hypoglycemia in children with type 1 diabetes: current issues and controversies","volume":"4","author":"Jones","year":"2003","journal-title":"Pediatr Diabetes"},{"key":"10.1111\/pedi.12088-BIB0058|pedi12088-cit-0058","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.2337\/diacare.22.7.1144","article-title":"Counterregulation during spontaneous nocturnal hypoglycemia in prepubertal children with type 1 diabetes","volume":"22","author":"Matyka","year":"1999","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0059|pedi12088-cit-0059","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0022-3476(97)70197-5","article-title":"Incidence and predictive criteria of nocturnal hypoglycemia in young children with insulin-dependent diabetes mellitus","volume":"130","author":"Porter","year":"1997","journal-title":"J Pediatr"},{"key":"10.1111\/pedi.12088-BIB0060|pedi12088-cit-0060","first-page":"229","article-title":"A conceptual overview and critique of functional neuroimaging techniques in humans: I. MRI\/FMRI and PET","volume":"9","author":"Aine","year":"1995","journal-title":"Crit Rev Neurobiol"},{"key":"10.1111\/pedi.12088-BIB0061|pedi12088-cit-0061","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s12031-007-0029-0","article-title":"Diffusion tensor imaging (DTI)-based white matter mapping in brain research a review","volume":"34","author":"Assaf","year":"2008","journal-title":"J Mol Neurosci"},{"key":"10.1111\/pedi.12088-BIB0062|pedi12088-cit-0062","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.2337\/db11-0589","article-title":"Prospectively determined impact of type 1 diabetes on brain volume during development","volume":"60","author":"Perantie","year":"2011","journal-title":"Diabetes"},{"key":"10.1111\/pedi.12088-BIB0063|pedi12088-cit-0063","doi-asserted-by":"crossref","first-page":"445","DOI":"10.2337\/dc08-1657","article-title":"Central nervous system function in youth with type 1 diabetes 12\u2009years after disease onset","volume":"32","author":"Northam","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0064|pedi12088-cit-0064","doi-asserted-by":"crossref","first-page":"922","DOI":"10.2337\/diacare.14.10.922","article-title":"Severe amnesia after hypoglycemia. Clinical, psychometric, and magnetic resonance imaging correlations","volume":"14","author":"Chalmers","year":"1991","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0065|pedi12088-cit-0065","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1046\/j.1464-5491.2001.00481.x","article-title":"Reversible amnesia in a Type 1 diabetic patient and bilateral hippocampal lesions on magnetic resonance imaging (MRI)","volume":"18","author":"Holemans","year":"2001","journal-title":"Diabet Med"},{"key":"10.1111\/pedi.12088-BIB0066|pedi12088-cit-0066","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1600-0404.1980.tb03047.x","article-title":"Effects of severe hypoglycemia on the human brain. Neuropathological case reports","volume":"62","author":"Kalimo","year":"1980","journal-title":"Acta Neurol Scand"},{"key":"10.1111\/pedi.12088-BIB0067|pedi12088-cit-0067","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.2337\/dc10-2164","article-title":"The feasibility of detecting neuropsychologic and neuroanatomic effects of type 1 diabetes in young children","volume":"34","author":"Aye","year":"2011","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0068|pedi12088-cit-0068","doi-asserted-by":"crossref","first-page":"236","DOI":"10.2337\/db09-1117","article-title":"Hippocampal volumes in youth with type 1 diabetes","volume":"59","author":"Hershey","year":"2010","journal-title":"Diabetes"},{"key":"10.1111\/pedi.12088-BIB0069|pedi12088-cit-0069","doi-asserted-by":"crossref","first-page":"2570","DOI":"10.2337\/dc12-0297","article-title":"Thalamic activation during slightly subphysiological glycemia in humans","volume":"35","author":"Arbelaez","year":"2012","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0070|pedi12088-cit-0070","doi-asserted-by":"crossref","first-page":"e60085","DOI":"10.1371\/journal.pone.0060085","article-title":"Comparison of regional cerebral blood flow responses to hypoglycemia using pulsed arterial spin labeling and positron emission tomography","volume":"8","author":"Arbelaez","year":"2013","journal-title":"PLoS One"},{"key":"10.1111\/pedi.12088-BIB0071|pedi12088-cit-0071","doi-asserted-by":"crossref","first-page":"6217","DOI":"10.1073\/pnas.0307048101","article-title":"Activation of human medial prefrontal cortex during autonomic responses to hypoglycemia","volume":"101","author":"Teves","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1111\/pedi.12088-BIB0072|pedi12088-cit-0072","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.neuroimage.2010.06.033","article-title":"Evolution and resolution of human brain perfusion responses to the stress of induced hypoglycemia","volume":"53","author":"Teh","year":"2010","journal-title":"Neuroimage"},{"key":"10.1111\/pedi.12088-BIB0073|pedi12088-cit-0073","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.jpeds.2008.03.005","article-title":"Prevalence of structural central nervous system abnormalities in early-onset type 1 diabetes mellitus","volume":"153","author":"Ho","year":"2008","journal-title":"J Pediatr"},{"key":"10.1111\/pedi.12088-BIB0074|pedi12088-cit-0074","doi-asserted-by":"crossref","first-page":"326","DOI":"10.2337\/diabetes.55.02.06.db05-0520","article-title":"Effects of type 1 diabetes on gray matter density as measured by voxel-based morphometry","volume":"55","author":"Musen","year":"2006","journal-title":"Diabetes"},{"issue":"Suppl. 2","key":"10.1111\/pedi.12088-BIB0075|pedi12088-cit-0075","first-page":"A57","article-title":"Evidence for reduced gray matter density in patients with type 1 diabetes as measured by magnetic resonance imaging","volume":"52","author":"Musen","year":"2004","journal-title":"Diabetes"},{"key":"10.1111\/pedi.12088-BIB0076|pedi12088-cit-0076","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1007\/s00125-006-0283-7","article-title":"Voxel-based morphometry demonstrates reduced grey matter density on brain MRI in patients with diabetic retinopathy","volume":"49","author":"Wessels","year":"2006","journal-title":"Diabetologia"},{"key":"10.1111\/pedi.12088-BIB0077|pedi12088-cit-0077","doi-asserted-by":"crossref","first-page":"17757","DOI":"10.1073\/pnas.1010459107","article-title":"Regional aerobic glycolysis in the human brain","volume":"107","author":"Vaishnavi","year":"2010","journal-title":"Proc Natl Acad Sci U\u00a0S\u00a0A"},{"key":"10.1111\/pedi.12088-BIB0078|pedi12088-cit-0078","first-page":"733","article-title":"Cranial CT in children and adolescents with diabetic ketoacidosis","volume":"9","author":"Hoffman","year":"1988","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1111\/pedi.12088-BIB0079|pedi12088-cit-0079","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1056\/NEJM198505023121803","article-title":"Subclinical brain swelling in children during treatment of diabetic ketoacidosis","volume":"312","author":"Krane","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1111\/pedi.12088-BIB0080|pedi12088-cit-0080","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1399-543X.2006.00156.x","article-title":"Frequency of sub-clinical cerebral edema in children with diabetic ketoacidosis","volume":"7","author":"Glaser","year":"2006","journal-title":"Pediatr Diabetes"},{"key":"10.1111\/pedi.12088-BIB0081|pedi12088-cit-0081","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/j.neuroimage.2006.04.187","article-title":"Diffusion tensor imaging of time-dependent axonal and myelin degradation after corpus callosotomy in epilepsy patients","volume":"32","author":"Concha","year":"2006","journal-title":"Neuroimage"},{"key":"10.1111\/pedi.12088-BIB0082|pedi12088-cit-0082","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/j.neuroimage.2004.03.041","article-title":"Diffusion tensor imaging detects early Wallerian degeneration of the pyramidal tract after ischemic stroke","volume":"22","author":"Thomalla","year":"2004","journal-title":"Neuroimage"},{"key":"10.1111\/pedi.12088-BIB0083|pedi12088-cit-0083","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1056\/NEJMoa1008069","article-title":"Detection of blast-related traumatic brain injury in U.S. military personnel","volume":"364","author":"Mac Donald","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1111\/pedi.12088-BIB0084|pedi12088-cit-0084","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.biopsych.2009.02.032","article-title":"Diffuse microstructural abnormalities of normal-appearing white matter in late life depression a diffusion tensor imaging study","volume":"66","author":"Shimony","year":"2009","journal-title":"Biol Psychiatry"},{"key":"10.1111\/pedi.12088-BIB0085|pedi12088-cit-0085","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.1523\/JNEUROSCI.4605-08.2009","article-title":"Axial diffusivity is the primary correlate of axonal injury in the experimental autoimmune encephalomyelitis spinal cord a quantitative pixelwise analysis","volume":"29","author":"Budde","year":"2009","journal-title":"J Neurosci"},{"key":"10.1111\/pedi.12088-BIB0086|pedi12088-cit-0086","doi-asserted-by":"crossref","first-page":"581","DOI":"10.2337\/db12-0696","article-title":"White matter microstructural integrity in youth with type 1 diabetes","volume":"62","author":"Antenor-Dorsey","year":"2013","journal-title":"Diabetes"},{"key":"10.1111\/pedi.12088-BIB0087|pedi12088-cit-0087","doi-asserted-by":"crossref","first-page":"e13463","DOI":"10.1371\/journal.pone.0013463","article-title":"Hyperglycemia induces oxidative stress and impairs axonal transport rates in mice","volume":"5","author":"Sharma","year":"2010","journal-title":"PLoS One"},{"key":"10.1111\/pedi.12088-BIB0088|pedi12088-cit-0088","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.2337\/dc12-0017","article-title":"White matter structural differences in young children with type 1 diabetes a diffusion tensor imaging study","volume":"35","author":"Aye","year":"2012","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0089|pedi12088-cit-0089","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1002\/mds.1110","article-title":"Hemiballism with hyperglycemia and striatal T1-MRI hyperintensity: an autopsy report","volume":"16","author":"Ohara","year":"2001","journal-title":"Mov Disord"},{"key":"10.1111\/pedi.12088-BIB0090|pedi12088-cit-0090","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S1474-4422(03)00554-4","article-title":"Hemiballism: revisiting a classic disorder","volume":"2","author":"Postuma","year":"2003","journal-title":"Lancet Neurol"},{"key":"10.1111\/pedi.12088-BIB0091|pedi12088-cit-0091","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.jpeds.2008.04.048","article-title":"Correlation of clinical and biochemical findings with diabetic ketoacidosis-related cerebral edema in children using magnetic resonance diffusion-weighted imaging","volume":"153","author":"Glaser","year":"2008","journal-title":"J Pediatr"},{"key":"10.1111\/pedi.12088-BIB0092|pedi12088-cit-0092","doi-asserted-by":"crossref","first-page":"e344","DOI":"10.1097\/PCC.0b013e3182196c9c","article-title":"Change in mean transit time, apparent diffusion coefficient, and cerebral blood volume during pediatric diabetic ketoacidosis treatment","volume":"12","author":"Vavilala","year":"2011","journal-title":"Pediatr Crit Care Med"},{"key":"10.1111\/pedi.12088-BIB0093|pedi12088-cit-0093","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jpeds.2004.03.045","article-title":"Mechanism of cerebral edema in children with diabetic ketoacidosis","volume":"145","author":"Glaser","year":"2004","journal-title":"J Pediatr"},{"key":"10.1111\/pedi.12088-BIB0094|pedi12088-cit-0094","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1212\/01.WNL.0000113760.72706.D2","article-title":"Diffusion tensor imaging of thalamus correlates with cognition in CADASIL without dementia","volume":"62","author":"O'Sullivan","year":"2004","journal-title":"Neurology"},{"key":"10.1111\/pedi.12088-BIB0095|pedi12088-cit-0095","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/01.wno.0000177307.21081.81","article-title":"Magnetic resonance spectroscopy","volume":"25","author":"Gujar","year":"2005","journal-title":"J Neuroophthalmol"},{"key":"10.1111\/pedi.12088-BIB0096|pedi12088-cit-0096","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1007\/s00234-005-1387-3","article-title":"Brain metabolite changes on proton magnetic resonance spectroscopy in children with poorly controlled type 1 diabetes mellitus","volume":"47","author":"Sarac","year":"2005","journal-title":"Neuroradiology"},{"key":"10.1111\/pedi.12088-BIB0097|pedi12088-cit-0097","doi-asserted-by":"crossref","first-page":"780","DOI":"10.3174\/ajnr.A1829","article-title":"Progressive decrease in N-acetylaspartate\/Creatine ratio in a teenager with type 1 diabetes and repeated episodes of ketoacidosis without clinically apparent cerebral edema: Evidence for permanent brain injury","volume":"31","author":"Wootton-Gorges","year":"2010","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1111\/pedi.12088-BIB0098|pedi12088-cit-0098","first-page":"895","article-title":"Cerebral proton magnetic resonance spectroscopy in children with diabetic ketoacidosis","volume":"28","author":"Wootton-Gorges","year":"2007","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1111\/pedi.12088-BIB0099|pedi12088-cit-0099","doi-asserted-by":"crossref","first-page":"470","DOI":"10.2337\/db07-1329","article-title":"Attenuation of counterregulatory responses to recurrent hypoglycemia by active thalamic inhibition a mechanism for hypoglycemia-associated autonomic failure","volume":"57","author":"Arbelaez","year":"2008","journal-title":"Diabetes"},{"key":"10.1111\/pedi.12088-BIB0100|pedi12088-cit-0100","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1126\/science.462184","article-title":"Metabolic mapping of functional activity in the hypothalamo-neurohypophysial system of the rat","volume":"205","author":"Schwartz","year":"1979","journal-title":"Science"},{"key":"10.1111\/pedi.12088-BIB0101|pedi12088-cit-0101","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1523\/JNEUROSCI.04-01-00251.1984","article-title":"Increased glucose metabolism during long-duration recurrent inhibition of hippocampal pyramidal cells","volume":"4","author":"Ackermann","year":"1984","journal-title":"J Neurosci"},{"key":"10.1111\/pedi.12088-BIB0102|pedi12088-cit-0102","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/S0893-6080(00)00063-0","article-title":"A model of working memory: bridging the gap between electrophysiology and human brain imaging","volume":"13","author":"Tagamets","year":"2000","journal-title":"Neural Netw"},{"key":"10.1111\/pedi.12088-BIB0103|pedi12088-cit-0103","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1002\/ana.410380408","article-title":"Cerebral transport and metabolism of 1-11C-D-glucose during stepped hypoglycemia","volume":"38","author":"Powers","year":"1995","journal-title":"Ann Neurol"},{"key":"10.1111\/pedi.12088-BIB0104|pedi12088-cit-0104","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.2337\/diabetes.50.8.1911","article-title":"Blood-to-brain glucose transport, cerebral glucose metabolism, and cerebral blood flow are not increased after hypoglycemia","volume":"50","author":"Segel","year":"2001","journal-title":"Diabetes"},{"key":"10.1111\/pedi.12088-BIB0105|pedi12088-cit-0105","unstructured":"Antenor-Dorsey JA Khoury N Su Y Adrenomedullary epinephrine response to declining plasma glucose concentrations is a signaling event that is not caused by a decrease in the cerebral metabolic rate of glucose 2013 62 Suppl. 1"},{"key":"10.1111\/pedi.12088-BIB0106|pedi12088-cit-0106","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1126\/science.3260686","article-title":"Nonoxidative glucose consumption during focal physiologic neural activity","volume":"241","author":"Fox","year":"1988","journal-title":"Science"},{"key":"10.1111\/pedi.12088-BIB0107|pedi12088-cit-0107","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.2337\/db11-1358","article-title":"Resting-state brain networks in type 1 diabetic patients with and without microangiopathy and their relation to cognitive functions and disease variables","volume":"61","author":"Duinkerken","year":"2012","journal-title":"Diabetes"},{"key":"10.1111\/pedi.12088-BIB0108|pedi12088-cit-0108","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/35094500","article-title":"Searching for a baseline: functional imaging and the resting human brain","volume":"2","author":"Gusnard","year":"2001","journal-title":"Nat Rev Neurosci"},{"key":"10.1111\/pedi.12088-BIB0109|pedi12088-cit-0109","first-page":"1267","volume-title":"The Cognitive Neurosciences","author":"Gusnard","year":"2004"},{"key":"10.1111\/pedi.12088-BIB0110|pedi12088-cit-0110","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/j.neuroimage.2007.02.041","article-title":"A default mode of brain function a brief history of an evolving idea","volume":"37","author":"Raichle","year":"2007","journal-title":"Neuroimage"},{"key":"10.1111\/pedi.12088-BIB0111|pedi12088-cit-0111","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1162\/jocn.1997.9.5.648","article-title":"Common blood flow changes across visual tasks: II. Decreases in cerebral cortex","volume":"9","author":"Shulman","year":"1997","journal-title":"J Cogn Neurosci"},{"key":"10.1111\/pedi.12088-BIB0112|pedi12088-cit-0112","doi-asserted-by":"crossref","first-page":"9673","DOI":"10.1073\/pnas.0504136102","article-title":"The human brain is intrinsically organized into dynamic, anticorrelated functional networks","volume":"102","author":"Fox","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1111\/pedi.12088-BIB0113|pedi12088-cit-0113","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1523\/JNEUROSCI.5062-08.2009","article-title":"Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease","volume":"29","author":"Buckner","year":"2009","journal-title":"J Neurosci"},{"key":"10.1111\/pedi.12088-BIB0114|pedi12088-cit-0114","doi-asserted-by":"crossref","first-page":"e597","DOI":"10.1371\/journal.pone.0000597","article-title":"Mapping human whole-brain structural networks with diffusion MRI","volume":"2","author":"Hagmann","year":"2007","journal-title":"PLoS One"},{"key":"10.1111\/pedi.12088-BIB0115|pedi12088-cit-0115","doi-asserted-by":"crossref","first-page":"7709","DOI":"10.1523\/JNEUROSCI.2177-05.2005","article-title":"Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory","volume":"25","author":"Buckner","year":"2005","journal-title":"J Neurosci"},{"key":"10.1111\/pedi.12088-BIB0116|pedi12088-cit-0116","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/aje\/154.7.635","article-title":"Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort","volume":"154","author":"Luchsinger","year":"2001","journal-title":"Am J Epidemiol"},{"key":"10.1111\/pedi.12088-BIB0117|pedi12088-cit-0117","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0166-4328(95)00153-0","article-title":"Glucose regulation and cognitive functions: relation to Alzheimer's disease and diabetes","volume":"75","author":"Messier","year":"1996","journal-title":"Behav Brain Res"},{"key":"10.1111\/pedi.12088-BIB0118|pedi12088-cit-0118","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1172\/JCI200319902","article-title":"Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose?","volume":"112","author":"Reusch","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1111\/pedi.12088-BIB0119|pedi12088-cit-0119","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.2337\/diacare.22.9.1438","article-title":"Predictors of change in the neuropsychological profiles of children with type 1 diabetes 2\u2009years after disease onset","volume":"22","author":"Northam","year":"1999","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0120|pedi12088-cit-0120","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1399-5448.2007.00274.x","article-title":"Effects of prior hypoglycemia and hyperglycemia on cognition in children with type 1 diabetes mellitus","volume":"9","author":"Perantie","year":"2008","journal-title":"Pediatr Diabetes"},{"key":"10.1111\/pedi.12088-BIB0121|pedi12088-cit-0121","doi-asserted-by":"crossref","first-page":"803","DOI":"10.2337\/diacare.20.5.803","article-title":"Attentional functioning in children and adolescents with IDDM","volume":"20","author":"Rovet","year":"1997","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0122|pedi12088-cit-0122","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0022-3476(99)70211-8","article-title":"The effect of hypoglycemic seizures on cognitive function in children with diabetes a 7-year prospective study","volume":"134","author":"Rovet","year":"1999","journal-title":"J Pediatr"},{"key":"10.1111\/pedi.12088-BIB0123|pedi12088-cit-0123","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1093\/jpepsy\/jsn074","article-title":"Neuro-cognitive performance in children with type 1 diabetes--a meta-analysis","volume":"34","author":"Naguib","year":"2009","journal-title":"J Pediatr Psychol"},{"key":"10.1111\/pedi.12088-BIB0124|pedi12088-cit-0124","doi-asserted-by":"crossref","first-page":"379","DOI":"10.2337\/diacare.21.3.379","article-title":"Neuropsychological complications of IDDM in children 2\u2009years after disease onset","volume":"21","author":"Northam","year":"1998","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0125|pedi12088-cit-0125","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1399-5448.2009.00588.x","article-title":"Neuropsychological profiles of young people with type 1 diabetes 12\u2009yr after disease onset","volume":"11","author":"Lin","year":"2010","journal-title":"Pediatr Diabetes"},{"key":"10.1111\/pedi.12088-BIB0126|pedi12088-cit-0126","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1469-8749.2012.04248.x","article-title":"Academic skills in children with early-onset type 1 diabetes: the effects of diabetes-related risk factors","volume":"54","author":"Hannonen","year":"2012","journal-title":"Dev Med Child Neurol"},{"key":"10.1111\/pedi.12088-BIB0127|pedi12088-cit-0127","doi-asserted-by":"crossref","first-page":"112","DOI":"10.2337\/diacare.26.1.112","article-title":"Factors associated with academic achievement in children with type 1 diabetes","volume":"26","author":"McCarthy","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1111\/pedi.12088-BIB0128|pedi12088-cit-0128","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1111\/j.1399-5448.2009.00532.x","article-title":"Type 1 diabetes mellitus and school a comparison of patients and healthy siblings","volume":"10","author":"Parent","year":"2009","journal-title":"Pediatr Diabetes"}],"container-title":["Pediatric Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpedi.12088","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpedi.12088","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/pedi.12088\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T18:06:31Z","timestamp":1671818791000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pedi.12088"}},"subtitle":["Glycemic extremes in youth with T1DM"],"short-title":[],"issued":{"date-parts":[[2013,10,14]]},"references-count":128,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,12]]}},"URL":"https:\/\/doi.org\/10.1111\/pedi.12088","archive":["Portico"],"relation":{},"ISSN":["1399-543X"],"issn-type":[{"value":"1399-543X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10,14]]}}}