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Here we review the literature regarding the prevalence, etiology, and management of renal dysfunction in pediatric liver transplant recipients. Long\u2010term studies suggest the prevalence of <jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content> to be 25\u201338% by 5\u201310\u00a0yr post\u2010transplant. While important, sole use of serum creatinine overestimates renal function in this population. Screening for and treatment of persistent proteinuria and hypertension as well as minimization of nephrotoxic insults are the mainstays to delay or prevent <jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content> progression. Office\u2010based blood pressure measures are less sensitive than <jats:styled-content style=\"fixed-case\">ABPM<\/jats:styled-content>, which is specifically recommended by the American Heart Association for its ability to diagnose masked hypertension in pediatric liver transplant recipients. Long\u2010term risk of <jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content> is predominantly secondary to <jats:styled-content style=\"fixed-case\">CNI<\/jats:styled-content> toxicity. <jats:styled-content style=\"fixed-case\">CNI<\/jats:styled-content> minimization protocols have shown promise in slowing progression of <jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content> while maintaining graft function, but large\u2010scale randomized control trials with long\u2010term follow\u2010up are needed.<\/jats:p>","DOI":"10.1111\/petr.12006","type":"journal-article","created":{"date-parts":[[2012,11,7]],"date-time":"2012-11-07T08:38:45Z","timestamp":1352277525000},"page":"818-828","source":"Crossref","is-referenced-by-count":17,"title":["The kidney in pediatric liver transplantation: An updated perspective"],"prefix":"10.1111","volume":"16","author":[{"given":"Robyn Greenfield","family":"Matloff","sequence":"first","affiliation":[{"name":"Division of Pediatric 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